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Research ArticleBrain

1H-MR Spectroscopy, Magnetization Transfer, and Diffusion-Weighted Imaging in Alcoholic and Nonalcoholic Patients with Cirrhosis with Hepatic Encephalopathy

F. Miese, G. Kircheis, H.J. Wittsack, F. Wenserski, J. Hemker, U. Mödder, D. Häussinger and M. Cohnen
American Journal of Neuroradiology May 2006, 27 (5) 1019-1026;
F. Miese
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G. Kircheis
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H.J. Wittsack
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F. Wenserski
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J. Hemker
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U. Mödder
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D. Häussinger
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M. Cohnen
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References

  1. ↵
    Häussinger D, Laubenberger J, vom Dahl S, et al., Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypo-osmolarity and hepatic encephalopathy. Gastroenterology 1994;107:1475–80
    CrossRefPubMedWeb of Science
  2. ↵
    Kreis R, Ross BD. Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: detection with proton MR spectroscopy. Radiology 1992;184:123–30
    PubMedWeb of Science
  3. ↵
    Laubenberger J, Haussinger D, Bayer S, et al., Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis. Gastroenterology 1997;112:1610–16
    CrossRefPubMedWeb of Science
  4. Cordoba J, Alonso J, Rovira A, et al. The development of low-grade cerebral edema in cirrhosis is supported by the evolution of (1)H-magnetic resonance abnormalities after liver transplantation. J Hepatol 2001;35:598–604
    CrossRefPubMedWeb of Science
  5. Geissler A, Lock G, Frund R, et al. Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging. Hepatology 1997;25:48–54
    CrossRefPubMedWeb of Science
  6. Ross BD, Jacobson S, Villamil F, et al. Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities. Radiology 1994;193:457–63
    PubMedWeb of Science
  7. ↵
    Lee JH, Seo DW, Lee YS, et al. Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve. Am J Gastroenterol 1999;94:2206–13
    CrossRefPubMed
  8. ↵
    Butterworth RF. Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies. J Hepatol 2003;39:278–85
    CrossRefPubMedWeb of Science
  9. Cordoba J, Sanpedro F, Alonso J, et al. 1H magnetic resonance in the study of hepatic encephalopathy in humans. Metab Brain Dis 2002;17:415–29
    CrossRefPubMedWeb of Science
  10. ↵
    Häussinger D, Kircheis G, Fischer R, et al. Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low-grade cerebral edema? J Hepatol 2000;32:1035–38
    CrossRefPubMedWeb of Science
  11. ↵
    Rovira A, Grive E, Pedraza S, et al. Magnetization transfer ratio values and proton MR spectroscopy of normal-appearing cerebral white matter in patients with liver cirrhosis. AJNR Am J Neuroradiol 2001;22:1137–42
    Abstract/FREE Full Text
  12. ↵
    Iwasa M, Kinosada Y, Nakatsuka A, et al. Magnetization transfer contrast of various regions of the brain in liver cirrhosis. AJNR Am J Neuroradiol 1999;20:652–54
    Abstract/FREE Full Text
  13. ↵
    Rovira A, Cordoba J, Sanpedro F, et al. Normalization of T2 signal abnormalities in hemispheric white matter with liver transplant. Neurology 2002;59:335–41
    Abstract/FREE Full Text
  14. ↵
    Lodi R, Tonon C, Stracciari A, et al. Diffusion MRI shows increased water apparent diffusion coefficient in the brains of cirrhotics. Neurology 2004 :62:762–66
    Abstract/FREE Full Text
  15. ↵
    Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60:646–49
    CrossRefPubMedWeb of Science
  16. ↵
    Schuhfried G. Wiener Test System (WINWTS). Schuhfried: Mödling, Austria;1999
  17. ↵
    Sinson G, Bagley LJ, Cecil KM, et al. Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. AJNR Am J Neuroradiol 2001;22:143–51
    Abstract/FREE Full Text
  18. ↵
    Ge Y, Grossman RI, Udupa JK, et al. Magnetization transfer ratio histogram analysis of gray matter in relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol 2001;22:470–75
    Abstract/FREE Full Text
  19. ↵
    Provencher SW. Automatic quantitation of localized in vivo 1H spectra with LCModel. NMR Biomed 2001;14:260–64
    CrossRefPubMedWeb of Science
  20. ↵
    Filippi M, Campi A, Dousset V, et al. A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis. Neurology 1995;45(3 Pt 1):478–82
  21. ↵
    Hahnel S, Munkel K, Jansen O, et al. Magnetization transfer measurements in normal-appearing cerebral white matter in patients with chronic obstructive hydrocephalus. J Comput Assist Tomogr 1999;23:516–20
    CrossRefPubMed
  22. ↵
    Brochet B, Dousset V. Pathological correlates of magnetization transfer imaging abnormalities in animal models and humans with multiple sclerosis. Neurology 1999;53(5 suppl 3):S12–17
  23. ↵
    Lansberg MG, Thijs VN, O’Brien MW, et al. Evolution of apparent diffusion coefficient, diffusion-weighted, and T2-weighted signal intensity of acute stroke. AJNR Am J Neuroradiol 2001;22:637–44
    Abstract/FREE Full Text
  24. ↵
    Gass A, Niendorf T, Hirsch JG. Acute and chronic changes of the apparent diffusion coefficient in neurological disorders: biophysical mechanisms and possible underlying histopathology. J Neurol Sci 2001;186(suppl 1):S15–23
  25. ↵
    Niendorf T, Dijkhuizen RM, Norris DG, et al. Biexponential diffusion attenuation in various states of brain tissue: implications for diffusion-weighted imaging. Magn Reson Med 1996;36:847–57
    PubMedWeb of Science
  26. Assaf Y, Cohen Y. Detection of different water populations in brain tissue using 2H single- and double-quantum-filtered diffusion NMR spectroscopy. J Magn Reson B 1996;112:151–59
    PubMed
  27. Mulkern RV, Gudbjartsson H, Westin CF, et al. Multi-component apparent diffusion coefficients in human brain. NMR Biomed 1999;12:51–62
    CrossRefPubMedWeb of Science
  28. ↵
    Chin CL, Wehrli FW, Hwang SN, et al. Biexponential diffusion attenuation in the rat spinal cord: computer simulations based on anatomic images of axonal architecture. Magn Reson Med 2002;47:455–60
    CrossRefPubMedWeb of Science
  29. ↵
    Kato M, Sugihara J, Nakamura T, et al. Electron microscopic study of the blood-brain barrier in rats with brain edema and encephalopathy due to acute hepatic failure. Gastroenterol Jpn 1989;24:135–42
    PubMed
  30. ↵
    Kato M, Hughes RD, Keays RT, et al. Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure. Hepatology 1992;15:1060–66
    CrossRefPubMedWeb of Science
  31. ↵
    Schweinsburg BC, Taylor MJ, Alhassoon OM, et al. Chemical pathology in brain white matter of recently detoxified alcoholics: a 1H magnetic resonance spectroscopy investigation of alcohol-associated frontal lobe injury. Alcohol Clin Exp Res 2001;25:924–34
    CrossRefPubMedWeb of Science
  32. ↵
    Pfefferbaum A, Sullivan EV. Microstructural but not macrostructural disruption of white matter in women with chronic alcoholism. Neuroimage 2002;15:708–18
    CrossRefPubMedWeb of Science
  33. ↵
    Chin JH, Goldstein DB. Drug tolerance in biomembranes: a spin label study of the effects of ethanol. Science 1977;196:684–85
    Abstract/FREE Full Text
  34. ↵
    Lee NM, Friedman HJ, Loh HH. Effect of acute and chronic ethanol treatment on rat brain phospholipid turnover. Biochem Pharmacol 1980;29:2815–18
    PubMed
  35. ↵
    Fralix TA, Ceckler TL, Wolff SD, et al. Lipid bilayer and water proton magnetization transfer: effect of cholesterol. Magn Reson Med 1991;18:214–23
    CrossRefPubMed
  36. ↵
    Parks MH, Dawant BM, Riddle WR, et al. Longitudinal brain metabolic characterization of chronic alcoholics with proton magnetic resonance spectroscopy. Alcohol Clin Exp Res 2002;26:1368–80
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 27 (5)
American Journal of Neuroradiology
Vol. 27, Issue 5
May 2006
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Cite this article
F. Miese, G. Kircheis, H.J. Wittsack, F. Wenserski, J. Hemker, U. Mödder, D. Häussinger, M. Cohnen
1H-MR Spectroscopy, Magnetization Transfer, and Diffusion-Weighted Imaging in Alcoholic and Nonalcoholic Patients with Cirrhosis with Hepatic Encephalopathy
American Journal of Neuroradiology May 2006, 27 (5) 1019-1026;

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1H-MR Spectroscopy, Magnetization Transfer, and Diffusion-Weighted Imaging in Alcoholic and Nonalcoholic Patients with Cirrhosis with Hepatic Encephalopathy
F. Miese, G. Kircheis, H.J. Wittsack, F. Wenserski, J. Hemker, U. Mödder, D. Häussinger, M. Cohnen
American Journal of Neuroradiology May 2006, 27 (5) 1019-1026;
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  • J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy
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  • Multimodality MR Imaging Findings of Low-Grade Brain Edema in Hepatic Encephalopathy
  • Modulation of neural activation following treatment of hepatic encephalopathy
  • Acute Hepatic Encephalopathy: Diffusion-Weighted and Fluid-Attenuated Inversion Recovery Findings, and Correlation with Plasma Ammonia Level and Clinical Outcome
  • Brain MR Imaging and 1H-MR Spectroscopy Changes in Patients with Extrahepatic Portal Vein Obstruction from Early Childhood to Adulthood
  • Pathogenetic mechanisms of hepatic encephalopathy
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