Article Figures & Data
Tables
Protocol TR (ms) TE (ms) Flip Angle No. of Sections Section (mm) Gap (mm) No. of Frames Total Time (sec) Contrast Clinical bolus 2000 60 60 14 7 2 34 68 100 μmol/kg at 3 mL/s Quantitative bolus 1150 35 90 12 5 1 42 48 65 μmol/kg at 3 mL/s Quantitative infusion 2500 35 90 12 5 1 42 105 120 μmol/kg at 1 mL/s* * Note that gadolinium is diluted before infusion.4
Clinical Quantitative Infusion* Cortical gray matter CBV (mL/g) 0.082 ± 0.019 0.042 ± 0.015 0.030 ± 0.006 MTT (s) 3.3 ± 1.0 3.6 ± 0.7 CBF (mL/100 g/min) 158.2 ± 37.7 75.6 ± 30.3 52.3 ± 13.7 Deep gray matter CBV (mL/g) 0.064 ± 0.016 0.038 ± 0.010 0.027 ± 0.003 MTT (s) 2.6 ± 0.7 2.9 ± 0.4 CBF (mL/100 g/min) 157.7 ± 60.9 81.3 ± 29.8 57.3 ± 11.2 White matter CBV (mL/g) 0.040 ± 0.012 0.025 ± 0.007 0.018 ± 0.003 MTT (s) 4.3 ± 1.6 4.9 ± 1.4 CBF (mL/100 g/min) 59.7 ± 19.9 32.5 ± 9.8 23.9 ± 5.1 Note:—CBV indicates cerebral blood volume; MTT, mean transit time; CBF, cerebral blood flow. Values are subject means ± SD.
* Infusion CBF was calculated using MTT from the quantitative bolus.