Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain

Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study

E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal and H. Zeumer
American Journal of Neuroradiology August 2006, 27 (7) 1426-1431;
E. Goebell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J. Fiehler
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
X.-Q. Ding
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Paustenbach
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Nietz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
O. Heese
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Kucinski
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. Hagel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Westphal
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Zeumer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Scherer H. The forms of growth in gliomas and their practical significance. Brain 1940;63:1–35
    FREE Full Text
  2. ↵
    Giese A, Bjerkvig R, Berens ME, et al. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003;21:1624–36
    Abstract/FREE Full Text
  3. ↵
    Tonn JC, Goldbrunner R. Mechanisms of glioma cell invasion. Acta Neurochir Suppl 2003;88:163–67
    PubMed
  4. ↵
    Demuth T, Berens ME. Molecular mechanisms of glioma cell migration and invasion. J Neurooncol 2004;70:217–28
    CrossRefPubMed
  5. ↵
    Hansen JR. Pulsed NMR study of water mobility in muscle and brain tissue. Biochim Biophys Acta 1971;230:482–86
    PubMed
  6. ↵
    Chenevert TL, Brunberg JA, Pipe JG. Anisotropic diffusion in human white matter: demonstration with MR techniques in vivo. Radiology 1990;177:401–05
    PubMedWeb of Science
  7. ↵
    Gass A, Niendorf T, Hirsch JG. Acute and chronic changes of the apparent diffusion coefficient in neurological disorders–biophysical mechanisms and possible underlying histopathology. J Neurol Sci 2001;186 Suppl 1:S15–23
  8. Le Bihan D, Mangin JF, Poupon C, et al. Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 2001;13:534–46
    CrossRefPubMedWeb of Science
  9. ↵
    Fiehler J. Editorial comment–ADC and metabolites in stroke: even more confusion about diffusion? Stroke 2003;34:e87–88
    FREE Full Text
  10. ↵
    Inoue T, Ogasawara K, Beppu T, et al. Diffusion tensor imaging for preoperative evaluation of tumor grade in gliomas. Clin Neurol Neurosurg 2005;107:174–80
    CrossRefPubMedWeb of Science
  11. ↵
    Beppu T, Inoue T, Shibata Y, et al. Measurement of fractional anisotropy using diffusion tensor MRI in supratentorial astrocytic tumors. J Neurooncol 2003;63:109–16
    CrossRefPubMed
  12. Field A, Alexander AL. The role of diffusion tensor imaging in cerebral tumor diagnosis and therapy. Presented at Symposium 2004: Integration of Imaging Strategies in Neuroradiology, and ASNR 42nd Annual Meeting; June 5–11,2004; Seattle, Wash.
  13. Sinha S, Bastin ME, Whittle IR, et al. Diffusion tensor MR imaging of high-grade cerebral gliomas. AJNR Am J Neuroradiol 2002;23:520–27
    Abstract/FREE Full Text
  14. ↵
    Tropine A, Vucurevic G, Delani P, et al. Contribution of diffusion tensor imaging to delineation of gliomas and glioblastomas. J Magn Reson Imaging 2004;20:905–12
    CrossRefPubMed
  15. ↵
    Majos C, Alonso J, Aguilera C, et al. Proton magnetic resonance spectroscopy (1H MRS) of human brain tumours: assessment of differences between tumour types and its applicability in brain tumour categorization. Eur Radiol 2003;13:582–91
    PubMed
  16. Smith JK, Castillo M, Kwock L. MR spectroscopy of brain tumors. Magn Reson Imaging Clin N Am 2003;11:415–29, v–vi
    CrossRefPubMed
  17. Law M, Yang S, Wang H, et al. Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol 2003;24:1989–98
    Abstract/FREE Full Text
  18. Tate AR, Majos C, Moreno A, et al. Automated classification of short echo time in in vivo 1H brain tumor spectra: a multicenter study. Magn Reson Med 2003;49:29–36
    CrossRefPubMedWeb of Science
  19. ↵
    Rabinov JD, Lee PL, Barker FG, et al. In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. Radiology 2002;225:871–79
    PubMedWeb of Science
  20. ↵
    Gupta RK, Sinha U, Cloughesy TF, et al. Inverse correlation between choline magnetic resonance spectroscopy signal intensity and the apparent diffusion coefficient in human glioma. Magn Reson Med 1999;41:2–7
    CrossRefPubMedWeb of Science
  21. ↵
    Yin H, Lim CC, Ma L, et al. Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis. J Neurol 2004;251:1249–54
    CrossRefPubMed
  22. ↵
    Eichler FS, Itoh R, Barker PB, et al. Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience. Radiology 2002;225:245–52
    PubMedWeb of Science
  23. ↵
    Ott D, Hennig J, and Ernst T. Human brain tumors: assessment with in vivo proton MR spectroscopy. Radiology 1993;186:745–52
    PubMedWeb of Science
  24. Poptani H, Gupta RK, Roy R, et al. Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. AJNR Am J Neuroradiol 1995;16:1593–603
    Abstract
  25. Preul MC, Caramanos Z, Collins DL, et al. Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy. Nat Med 1996;2:323–25
    CrossRefPubMedWeb of Science
  26. ↵
    Negendank WG, Sauter R, Brown TR, et al. Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study. J Neurosurg 1996;84:449–58
    CrossRefPubMedWeb of Science
  27. ↵
    Moeller-Hartmann W. Practical application of proton magnetic resonance spectroscopy to the diagnostics of focal intracranial mass lesions. Clin Neuroradiol 2005;15:62–78
  28. ↵
    Eichler FS, Barker PB, Cox C, et al. Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy. Neurology 2002;58:901–07
    Abstract/FREE Full Text
  29. ↵
    Field AS, Alexander AL, Wu YC, et al. Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumor. J Magn Reson Imaging 2004;20:555–62
    CrossRefPubMed
  30. Ulmer JL, Salvan CV, Mueller WM, et al. The role of diffusion tensor imaging in establishing the proximity of tumor borders to functional brain systems: implications for preoperative risk assessments and postoperative outcomes. Technol Cancer Res Treat 2004;3:567–76
    Abstract/FREE Full Text
  31. ↵
    Nimsky C, Ganslandt O, Hastreiter P, et al. Intraoperative diffusion-tensor MR imaging: shifting of white matter tracts during neurosurgical procedures–initial experience. Radiology 2005;234:218–25
    PubMedWeb of Science
  32. ↵
    Pierpaoli C, Jezzard P, Basser PJ, et al. Diffusion tensor MR imaging of the human brain. Radiology 1996;201:637–48
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 27 (7)
American Journal of Neuroradiology
Vol. 27, Issue 7
August 2006
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal, H. Zeumer
Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study
American Journal of Neuroradiology Aug 2006, 27 (7) 1426-1431;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study
E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal, H. Zeumer
American Journal of Neuroradiology Aug 2006, 27 (7) 1426-1431;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Patients and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Associating IDH and TERT Mutations in Glioma with Diffusion Anisotropy in Normal-Appearing White Matter
  • Associating IDH and TERT Mutations in Glioma with Diffusion Anisotropy in Normal-Appearing White Matter
  • Pushing the Limits of Glioma Resection Using Electrophysiologic Brain Mapping
  • A change in the apparent diffusion coefficient after treatment with bevacizumab is associated with decreased survival in patients with recurrent glioblastoma multiforme
  • Diffusion Tensor MR Imaging of Cerebral Gliomas: Evaluating Fractional Anisotropy Characteristics
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Fast Contrast-Enhanced 4D MRA and 4D Flow MRI Using Constrained Reconstruction (HYPRFlow): Potential Applications for Brain Arteriovenous Malformations
  • Multimodal CT Provides Improved Performance for Lacunar Infarct Detection
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire