Article Figures & Data
Figures
- Fig 1.
Cortical ischemic lesions identified by high resolution diffusion-weighted imaging (bottom), missed by conventional DWI (top). Note in the magnifications, the location of the lesions mainly along the cortical gray ribbon.
- Fig 2.
Thresholded binary images resulting from source diffusion-weighted images (DWI) in 2 gradient directions at the top left and center, and from source high-resolution diffusion-weighted images (DWI-HR) at the bottom left and center. Note the greater anteroposterior shift on the image resulting from the DWI source images subtraction at the top right compared with the one resulting from the dual-echo corrected DWI-HR source images at the bottom left.
Tables
Discrete lesions identified on diffusion-weighted MR imaging (DWI) and high-resolution DWI (DWI-HR)
DWI DWI-HR P Value Signal-to-noise ratio, mean (range) 29.7 (23.9–37) 35.6 (27.7–43.2) <.01 Contrast-to-noise ratio, mean (range) 10.7 (8–17) 14.8 (12.6–20.6) <.01 Total no. of lesions 129 253 <.001 Average no. of lesions 3.07 6.04 <.001 No. of unique lesions 7 123 <.001 Total lesion volume (mm3) 7040 ± 2010 7052 ± 1950 .95 Average volume per lesion (mm3) 3600 ± 1300 2800 ± 1200 <.001 Average volume per lesion of unique lesions (mm3) 134.41 ± 88.23 70.50 ± 16.90 .65 No. of patients with a single lesions, n (%) 16 (37%) 12 (28%) n/a Number of patients with greater than 5 lesions, n (%) 8 (19%) 19 (42%) n/a Note:—DWI-HR was acquired following a tetrahedronal encoding scheme with the following gradient directions: (0, 1, 1), (−1, 0, 1), (0, 1, 1), (1, 1, 0), (0, 1, −1), (−1, 1, 0). 100% gradient strength was applied simultaneously along 2 axes affecting a factor of 2 gain in ‖b‖, and allowing for a shorter echo time.
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