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Research ArticleBrain

Underestimation of Cerebral Perfusion on Flow-Sensitive Alternating Inversion Recovery Image: Semiquantitative Evaluation with Time-to-Peak Values

H.S. Kim, S.Y. Kim and J.M. Kim
American Journal of Neuroradiology November 2007, 28 (10) 2008-2013; DOI: https://doi.org/10.3174/ajnr.A0720
H.S. Kim
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S.Y. Kim
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J.M. Kim
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  • Fig 1.
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    Fig 1.

    The 3 FAIR maps with use of different TIs: (A) 800 ms, (B) 1200 ms, and (C) 1600 ms; and the corresponding TTP map with ROI (D), and a CBF map (E) obtained from the DSC MR image of a 56-year-old man with severe stenosis of the left proximal ICA. The area of decreased CBF (arrows) on the FAIR map with the shortest (800 ms) and intermediate (1200 ms) TIs is larger than those on the FAIR maps with the longest TI (1600 ms).

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    Fig 2.

    A stem-and-leaf plot of the rCBFs between the ipsilateral lesions and contralateral normal areas on the 3 FAIR images in the area with less prolonged TTP (dTTP <3.2 s) (FAIR, 800 ms; TI, 800 ms; FAIR, 1200 ms; TI, 1200 ms; FAIR, 1600 ms; TI, 1600 ms).

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    Fig 3.

    A stem-and-leaf plot of the rCBFs between the ipsilateral lesions and contralateral normal areas on the 3 FAIR images in the area with more prolonged TTP (dTTP ≥3.2 s) (FAIR, 800 ms; TI, 800 ms; FAIR, 1200 ms; TI, 1200 ms; FAIR, 1600 ms; TI, 1600 ms).

Tables

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    Table 1:

    Width of decreased CBFs among the three FAIR maps with different inversion times according to the TTP difference

    wCBFdTTP <3.2 s (%)dTTP ≥3.2 s (%)
    FAIR 800 < FAIR 12000/25 (0)0/17 (0)
    FAIR 800 = FAIR 120023/25 (92)12/17 (71)
    FAIR 800 > FAIR 12002/25 (8)5/17 (29)
    FAIR 800 < FAIR 16000/25 (0)0/17 (0)
    FAIR 800 = FAIR 160017/25 (68)3/17 (18)
    FAIR 800 > FAIR 16008/25 (32)14/17 (82)
    FAIR 1200 < FAIR 16000/25 (0)0/17 (0)
    FAIR 1200 = FAIR 160022/25 (88)5/17 (29)
    FAIR 1200 > FAIR 16003/25 (12)12/17 (71)
    • Note:—wCBF, width of decreased CBF; dTTP, TTP difference; FAIR 800, TI = 800 ms; FAIR 1200, TI = 1200 ms; FAIR 1600, TI = 1600 ms.

    • View popup
    Table 2:

    Correlation coefficients of rCBF among the three FAIR maps

    GroupsdTTP <3.2 sdTTP ≥3.2 s
    FAIR 800 vs FAIR 1200r = 0.764, P < .01r = 0.712, P < .01
    FAIR 800 vs FAIR 1600r = 0.667, P < .01r = 0.595, P < .01
    FAIR 1200 vs FAIR 1600r = 0.791, P < .01r = 0.612, P < .01
    • Note:—dTTP indicates TTP difference; FAIR 800, TI = 800 ms; FAIR 1200, TI = 1200 ms; FAIR 1600, TI = 1600 ms; r, correlation coefficient.

    • View popup
    Table 3:

    Comparison of rCBF among the three FAIR images in the areas with less prolonged TTP (dTTP <3.2 s)*

    ComparisonMDP Value95% CI
    FAIR 800 vs FAIR 1200−0.031<.05−0.060-−0.003
    FAIR 800 vs FAIR 1600−0.046<.001−0.075-−0.017
    FAIR 1200 vs FAIR 1600−0.015>.05−0.043-−0.014
    • Note:—MD indicates mean difference; CI, confidence interval; FAIR 800, TI = 800 ms; FAIR 1200, TI = 1200 ms; FAIR 1600, TI = 1600 ms.

    • * Statistical analysis was performed with the repeated measures ANOVA and post hoc analysis with the Tukey-Kramer multiple comparisons test.

    • View popup
    Table 4:

    Comparison of rCBF among the three FAIR images in the area with more prolonged TTP (dTTP ≥3.2 s)*

    ComparisonMDP Value95% CI
    FAIR 800 vs FAIR 1200−0.026<.05−0.049-−0.002
    FAIR 800 vs FAIR 1600−0.078<.001−0.101-−0.054
    FAIR 1200 vs FAIR 1600−0.052<.001−0.075-−0.029
    • Note:—MD indicates mean difference; CI, confidence interval; FAIR 800, TI = 800 ms; FAIR 1200, TI = 1200 ms; FAIR 1600, TI = 1600 ms.

    • * Statistical analysis was performed with the repeated measures ANOVA and post hoc analysis with the Tukey-Kramer multiple comparisons test.

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American Journal of Neuroradiology: 28 (10)
American Journal of Neuroradiology
Vol. 28, Issue 10
November 2007
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H.S. Kim, S.Y. Kim, J.M. Kim
Underestimation of Cerebral Perfusion on Flow-Sensitive Alternating Inversion Recovery Image: Semiquantitative Evaluation with Time-to-Peak Values
American Journal of Neuroradiology Nov 2007, 28 (10) 2008-2013; DOI: 10.3174/ajnr.A0720

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Underestimation of Cerebral Perfusion on Flow-Sensitive Alternating Inversion Recovery Image: Semiquantitative Evaluation with Time-to-Peak Values
H.S. Kim, S.Y. Kim, J.M. Kim
American Journal of Neuroradiology Nov 2007, 28 (10) 2008-2013; DOI: 10.3174/ajnr.A0720
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