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Research ArticleBrain

Focal Brain Glucose Hypometabolism in Patients with Neuropsychologic Deficits after Diffuse Axonal Injury

T. Nakashima, N. Nakayama, K. Miwa, A. Okumura, A. Soeda and T. Iwama
American Journal of Neuroradiology February 2007, 28 (2) 236-242;
T. Nakashima
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N. Nakayama
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K. Miwa
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A. Okumura
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A. Soeda
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T. Iwama
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  • Fig 1.
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    Fig 1.

    Z-score brain surface map represents areas of metabolic reduction in patients in comparison with healthy subjects (data base group). Right lateral (R.LAT), left lateral (L. LAT), superior (SUP), inferior (INF), anterior (ANT), posterior (POST), right medial (R. MED), and left medial (L. MED) views are shown. Reduction of glucose metabolism is evident in medial aspects of cerebrum especially in cingulate gyrus, lingual gyrus, and cuneus.

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    Fig 2.

    Z-score brain surface map represents the result of group comparison between 2 healthy subjects groups such as control group (CG) and data base group (DBG). Right lateral (R.LAT), left lateral (L. LAT), superior (SUP), inferior (INF), anterior (ANT), posterior (POST), right medial (R. MED), and left medial (L. MED) views are shown. Marked metabolic reduction is not shown on the medial surface of cerebrum.

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    Fig 3.

    Z-score brain surface map of representative cases shows a prominent metabolic reduction on respective gyrus level segment in cingulate gyrus.

    Top, 46-year-old man (case 4) shows hypometabolism in anterior cingulate gyrus.

    Middle, 38-year-old woman (case 7) shows hypometabolism in middle cingulate gyrus. Metabolic reduction shown in the right frontal lobe is the result of cerebral contusion.

    Bottom, 28-year-old man (case 12) shows hypometabolism in posterior cingulate gyrus with concomitant hypometabolism of lingual gyrus and cuneus.

Tables

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    Table 1:

    Abstract from the stereotactic extraction estimation (SEE) results of group comparison

    Gyrus Level ClassificationTotal ProjectionProjection (Z > 2)Extent Ratio (%)
    Anterior cingulate gyrus
        Left1809452.2
        Right1808547.2
    Middle cingulate gyrus
        Left26711844.2
        Right2679435.2
    Posterior cingulate gyrus
        Left985859.2
        Right984343.9
    Lingual gyrus
        Left1008989.0
        Right999191.9
    Cuneus
        Left30611938.9
        Right30312741.9
    • Note:—In each row, anatomic information, total coordinates, number of coordinates showing abnormalities (Z > 2), and proportion of abnormal pixels in total surface pixels are presented from the left. Table shows the results of representative gyrus level segments extracted from 32 segments of whole cerebral surface.

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    Table 2:

    Proportion of surface pixels showing abnormalities (Z > 2) in each case

    Case No.Age & SexAnterior Cingulate GyrusMiddle Cingulate GyrusPosterior Cingulate GyrusLingual Gyrus
    RightLeftRightLeftRightLeftRightLeft
    126 F37.858.99.02.62.00.00.00.0
    239 M20.015.69.711.22.00.06.125.0
    350 M34.432.829.238.22.01.00.03.0
    446 M45.648.932.224.710.28.20.02.0
    524 F57.246.19.73.07.15.134.333.0
    622 M57.837.86.04.54.124.535.452.0
    738 F1.12.811.213.92.01.00.016.0
    823 M1.75.616.115.41.01.00.033.0
    922 M1.10.01.11.916.321.417.221.0
    1044 F0.00.02.62.653.16.169.76.0
    1119 M1.70.65.21.93.111.272.772.0
    1228 M2.27.82.26.742.943.923.261.0
    CGMean2.31.80.91.90.92.56.59.9
    SD2.82.80.92.42.04.211.917.4
    • Note:—CG indicates control group.

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American Journal of Neuroradiology: 28 (2)
American Journal of Neuroradiology
Vol. 28, Issue 2
February 2007
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Cite this article
T. Nakashima, N. Nakayama, K. Miwa, A. Okumura, A. Soeda, T. Iwama
Focal Brain Glucose Hypometabolism in Patients with Neuropsychologic Deficits after Diffuse Axonal Injury
American Journal of Neuroradiology Feb 2007, 28 (2) 236-242;

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Focal Brain Glucose Hypometabolism in Patients with Neuropsychologic Deficits after Diffuse Axonal Injury
T. Nakashima, N. Nakayama, K. Miwa, A. Okumura, A. Soeda, T. Iwama
American Journal of Neuroradiology Feb 2007, 28 (2) 236-242;
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