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Research ArticleINTERVENTIONAL

Reduction of Radiation Dose for Cerebral Angiography Using Flat Panel Detector of Direct Conversion Type: A Vascular Phantom Study

Y. Hatakeyama, S. Kakeda, N. Ohnari, J. Moriya, N. Oda, K. Nishino, W. Miyamoto and Y. Korogi
American Journal of Neuroradiology April 2007, 28 (4) 645-650;
Y. Hatakeyama
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S. Kakeda
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N. Ohnari
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J. Moriya
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N. Oda
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K. Nishino
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W. Miyamoto
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Y. Korogi
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    Fig 1.

    Photograph (A) and schematic drawing (B) of the anthropomorphic vascular phantom used in this study. The phantom was designed to simulate the intracranial arteries with a total of 32 aneurysms. Of 32 aneurysms, 15 had a bleb with diameter of 2 mm.

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    Fig 2.

    ROC curves for the detection of simulated aneurysmal blebs with 3 different contrast material concentrations: 300 mg I/mL (A), 150 mg I/mL (B), and 100 mg I/mL (C). For each contrast material concentration, graph shows the 3 composite ROC curves generated from the pooled data of the 7 observers’ results with the standard- (solid line) and low-dose modes of FPD (dashed line) and the conventional-dose mode of I.I.-TV (dotted line) systems.

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    Fig 3.

    2D DSA from the left anterior oblique view at 300 mg I/mL obtained with standard-dose mode of FPD system (A), with low-dose mode of FPD system (B), and with conventional-dose mode of I.I.-TV system shows blebs (arrows) (C). For the depiction of aneurysmal blebs, there is no particular difference among the 3 dose modes.

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    Fig 4.

    2D DSA from the left anterior oblique view at 100 mg I/mL obtained with standard-dose mode of FPD (A), with low-dose mode of FPD (B), and with conventional-dose mode of I.I.-TV system shows blebs (arrows) (C). For the depiction of aneurysmal blebs, the images obtained with both dose modes of FPD system are superior to those obtained with the I.I.-TV system.

Tables

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    Table 1:

    Technical features of FPD system and I.I.-TV system

    FeatureFPD systemI.I.-TV system
    Total filtration3 mm of Al + 0.3 mm of Cu3 mm of Al
    Additional filtrationNoneNone
    Frame rate
        Cine mode30 fps30 fps
        Fluoroscopy mode15 fps15 fps
    Image matrix format1440 × 14401024 × 1024
    Field of view9 inches12 inches
    • Note:—FPD indicates flat panel detector; I.I.-TV, image intensifier television; fps, frames per second.

    • View popup
    Table 2:

    Subjective evaluation for the 2D DSA regarding the depiction of simulated aneurysms

    Contrast Material Concentration & Dose ModeScore for Image QualityP
    54321Mean ± SD*
    300 mgI/mL
        Standard-dose mode of FPD system5700005.00 ± 0.00**.038
        Low-dose mode of FPD system5700005.00 ± 0.00**.038
        Conventional-dose mode of I.I.-TV system5232004.88 ± 0.43
    150 mgI/mL
        Standard-dose mode of FPD system5511004.95 ± 0.29**<.001
        Low-dose mode of FPD system5241004.90 ± 0.36**<.001
        Conventional-dose mode of I.I.-TV system41105104.60 ± 0.73
    100 mgI/mL
        Standard-dose mode of FPD system41124004.65 ± 0.61**<.001
        Low-dose mode of FPD system39135004.60 ± 0.65**<.001
        Conventional-dose mode of I.I.-TV system115261323.00 ± 0.85
    • Note:—DSA indicates digital subtraction angiography; FPD, flat panel detector; I.I.-TV, image intensifier television. Data are mean ± SD of scores for image quality evaluated using a 5-point scale (1, clearly visualized; 2, good; 3, reasonably good; 4, poor; 5, very poor)

    • ** Significantly higher to I.I.-TV system (the Wilcoxon signed rank test).

    • View popup
    Table 3:

    Diagnostic performance according of each observer regarding the detection of the simulated aneurysmal blebs

    Contrast Material Concentration & Dose ModeObserverMean Az
    1234567
    300 mgI/mL
        Standard-dose mode of FPD system0.930.910.890.920.910.920.940.92
        Low-dose mode of FPD system0.890.890.910.920.920.940.950.92
        Conventional-dose mode of I.I.-TV system0.920.910.860.980.870.950.900.91
    150 mgI/mL
        Standard-dose mode of FPD system0.810.790.830.830.830.800.820.82
        Low-dose mode of FPD system0.830.790.850.820.830.850.840.83
        Conventional-dose mode of I.I.-TV system0.800.780.850.810.820.840.820.82
    100 mgI/mL
        Standard-dose mode of FPD system0.840.880.870.800.930.870.800.86*
        Low-dose mode of FPD system0.840.880.860.790.930.870.790.85*
        Conventional-dose mode of I.I.-TV system0.670.550.540.570.550.540.520.56
    • Note:—Az indicates areas under the receiver operating characteristic curve; FPD, flat panel detector; I.I.-TV, image intensifier television.

    • * Significantly higher to I.I.-TV system (P < .01).

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American Journal of Neuroradiology: 28 (4)
American Journal of Neuroradiology
Vol. 28, Issue 4
April 2007
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Y. Hatakeyama, S. Kakeda, N. Ohnari, J. Moriya, N. Oda, K. Nishino, W. Miyamoto, Y. Korogi
Reduction of Radiation Dose for Cerebral Angiography Using Flat Panel Detector of Direct Conversion Type: A Vascular Phantom Study
American Journal of Neuroradiology Apr 2007, 28 (4) 645-650;

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Reduction of Radiation Dose for Cerebral Angiography Using Flat Panel Detector of Direct Conversion Type: A Vascular Phantom Study
Y. Hatakeyama, S. Kakeda, N. Ohnari, J. Moriya, N. Oda, K. Nishino, W. Miyamoto, Y. Korogi
American Journal of Neuroradiology Apr 2007, 28 (4) 645-650;
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