Article Figures & Data
Figures
- Fig 1.
Left vertebral injection left anterior oblique (LAO) (A) and lateral (B) views demonstrate severe vasospasm of the distal basilar artery after SAH secondary to dissecting right vertebral aneurysm, treated with parent vessel occlusion with coils.
- Fig 2.
After a total 40 mg of intra-arterial nicardipine infusion (3 vascular territories injected). Almost total restoration of the vessel diameter is demonstrated.
- Fig 3.
Right internal carotid artery (ICA) injection, lateral projection demonstrates severe vasospasm of the supraclinoid ICA after SAH.
- Fig 4.
After nicardipine infusion, there is more than 60% vessel diameter restoration.
Tables
- Table 1:
Vasospasm site and nicardipine treatment data for study patients (n = 11) and procedures (n = 20)
Patient Aneurysm Site Hunt and Hess Grade Surgery Vasospasm Symptoms Procedure Doses (mg) GCS SBP Pre Post Pre Post 1 L PComA I Clip 15, 25 13 14 2 R PComA IV Coil Paresis 10, 12 13 14 3 R MCA III Coil Paresis 25, 25, 12.5 13 14 197 160 4 L vertebral III Coil Paresis 40 6 14 201 179 5 AComA IV Coil 35 8 8 153 122 6 basilar IV Coil 25 5 14 7 AComA II Coil 11 12 15 169 122 8 L MCA III Clip Paresis, aphasia 35, 20, 20 9 11 188 129 9 basilar IV Coil Facial droop 25, 25 4 11 150 112 10 AComA I Coil Paresis 25, 30 13 15 190 170 11 R PComA II Coil Paresis 15, 10 14 15 199 192 Note:—GCS indicates Glasgow Coma Score; SBP, systolic blood pressure; L, left; R, right; PComA, posterior communicating artery; AComA, anterior communicating artery; MCA, middle cerebral artery. All patients had depressed level of consciousness.
Patient Total Nicardipine Dose (mg/procedure) Treated Vascular Territories 1 15, 25 L M1, A1 2 10, 12 R MCA 3 25, 25, 12.5 R MCA, ACA 4 40 Basilar, R MCA, L ICA 5 35 LTA1, LTA2, R A1, R A2 6 25 R MCA, L MCA, R PCA 7 11 R ICA, MCA, LICA 8 35, 20, 20 M1, A1 bilaterally 9 25, 25 A1, ICA bilaterally 10 25, 30 A1, ICA bilaterally 11 25, 30 R A1, A2, M2, M3 Note:—MCA indicates middle cerebral artery; ACA, anterior cerebral artery; PCA, posterior cerebral artery; ICA, internal carotid artery; M1, M1 segment of the MCA; M2, M2 segment of the MCA; M3, M3 segment of the MCA; A1, A1 segment of the ACA; A2, A2 segment of the ACA; LTA1, left A1 segment of the ACA; LTA2, left A2 segment of the ACA; L, left; R, right.
Patient Treatments Performed Interval between Treatments (days) 1 2 1 2 2 1 3 3 3,3 4 1 0 5 1 0 6 1 0 7 1 0 8 3 1,5 9 2 1 10 2 2 11 2 2
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