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Research ArticleBRAIN

Accuracy of Pre- and Postcontrast 3D Time-of-Flight MR Angiography in Patients with Acute Ischemic Stroke: Correlation with Catheter Angiography

H. Ishimaru, M. Ochi, M. Morikawa, H. Takahata, Y. Matsuoka, T. Koshiishi, T. Fujimoto, A. Egawa, K. Mitarai, T. Murakami and M. Uetani
American Journal of Neuroradiology May 2007, 28 (5) 923-926;
H. Ishimaru
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M. Ochi
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M. Morikawa
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H. Takahata
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Y. Matsuoka
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T. Koshiishi
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T. Fujimoto
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A. Egawa
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K. Mitarai
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T. Murakami
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M. Uetani
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    Fig 1.

    A 51-year-old man with progressive left-sided weakness, dysarthria, and impaired consciousness (patient 4). A, Axial DWI confirms infarction in the centrum semiovale. B, On 3D TOF MR angiogram (anteroposterior [AP] view), occlusion of the C4 segment of the right ICA is suspected. Antegrade filling of the MCA via an anterior communicating artery is identified. C, Relative mean transit time map shows a region of delayed flow in the right hemisphere. D, Depiction of the cavernous portion of the ICA is improved on postcontrast 3D TOF MR angiogram (AP view), which shows severe stenosis at the C2 portion of the ICA. Some contrast enhancement from the cavernous sinus is evident. E, Right internal carotid angiogram immediately after MR imaging examination shows severe stenosis at the C2 portion and delayed flow in the MCA territory, but no antegrade filling into the anterior cerebral artery territory (TIMI grade 1).

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    Fig 2.

    A 49-year-old man with sudden-onset left-sided paralysis, aphasia, and impaired consciousness (patient 6). A, Axial DWI obtained at the time of MRA confirms infarction of right MCA territory. B, 3D TOF MR angiogram (AP view) shows occlusion of the M1 segment of the right MCA. C, Relative mean transit time map shows a region of delayed flow in the right hemisphere. D, Postcontrast 3D TOF MR angiogram (AP view) shows improved depiction of the distal M1 portion and M2 branches. Some contrast enhancement from the cavernous sinus is evident. E, Right internal carotid angiogram immediately after MR imaging examination shows total occlusion (TIMI grade 0) of the M1 segment of the right MCA. Retrograde opacification of the MCA branches via pial collateral vessels extending from the anterior cerebral artery is noted; however, the vessel just distal to the occlusion is not delineated. F, Right internal carotid angiogram after the first trial of angioplasty by using the 9-mm-long balloon catheter at the occluded portion shows antegrade filling into the distal M1 portion and M2 branches through the residual stenosis. Note that postcontrast MR angiogram (D) precisely demonstrates the extent of the occlusion that is shown on catheter angiography during PTCBA procedures (F).

Tables

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  • Correlation between catheter and MR angiographic findings

    Catheter AngiographyTOF MR Angiography
    Proximal SideDistal Side
    PatientAge/ SexTIMI GradingPrePostPrePost
    161/MVA stenosis*22222
    271/MVA stenosis*12222
    388/FM1 stenosis12222
    451/MC2 stenosis10202
    585/MBA embolism1022†2
    649/MM1 occlusion02201
    768/FM2 occlusion02202
    859/FVA occlusion*00202
    972/MC4 occlusion00202
    1073/MM2 occlusion00202
    1177/MM1 occlusion00202
    1263/FM2 occlusion00202
    1361/FM2 occlusion002––
    • Note:—VA indicates vertebral artery; Pre, precontrast; Post, postcontrast; BA, basilar artery; M1, horizontal segment of the MCA; M2, insular segment of the MCA; C2, C2 segment of the ICA; C4, C4 segment of the ICA;

    • * , with contralateral VA occlusion;

    • † , cross-flow via posterior communicating artery; –, vessel distal to the occlusion was not included in the scanning range.

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American Journal of Neuroradiology: 28 (5)
American Journal of Neuroradiology
Vol. 28, Issue 5
May 2007
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H. Ishimaru, M. Ochi, M. Morikawa, H. Takahata, Y. Matsuoka, T. Koshiishi, T. Fujimoto, A. Egawa, K. Mitarai, T. Murakami, M. Uetani
Accuracy of Pre- and Postcontrast 3D Time-of-Flight MR Angiography in Patients with Acute Ischemic Stroke: Correlation with Catheter Angiography
American Journal of Neuroradiology May 2007, 28 (5) 923-926;

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Accuracy of Pre- and Postcontrast 3D Time-of-Flight MR Angiography in Patients with Acute Ischemic Stroke: Correlation with Catheter Angiography
H. Ishimaru, M. Ochi, M. Morikawa, H. Takahata, Y. Matsuoka, T. Koshiishi, T. Fujimoto, A. Egawa, K. Mitarai, T. Murakami, M. Uetani
American Journal of Neuroradiology May 2007, 28 (5) 923-926;
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Cited By...

  • Diagnostic Accuracy of High-Resolution Black-Blood MRI in the Evaluation of Intracranial Large-Vessel Arterial Occlusions
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • Prediction of Infarction and Reperfusion in Stroke by Flow- and Volume-Weighted Collateral Signal in MR Angiography
  • Imaging in children presenting with acute neurological deficit: stroke
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