Research ArticlePediatric Neuroimaging
The Normal Neonatal Brain: MR Imaging, Diffusion Tensor Imaging, and 3D MR Spectroscopy in Healthy Term Neonates
A.I. Bartha, K.R.L. Yap, S.P. Miller, R.J. Jeremy, M. Nishimoto, D.B. Vigneron, A.J. Barkovich and D.M. Ferriero
American Journal of Neuroradiology June 2007, 28 (6) 1015-1021; DOI: https://doi.org/10.3174/ajnr.A0521
A.I. Bartha
K.R.L. Yap
S.P. Miller
R.J. Jeremy
M. Nishimoto
D.B. Vigneron
A.J. Barkovich

References
- ↵Ferriero DM. Neonatal brain injury. N Engl J Med 2004;351:1985–95
- Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 2005;365:663–70
- Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005;353:1574–84
- ↵
- ↵Barkovich AJ. MR imaging of the neonatal brain. Neuroimaging Clin N Am 2006;16:117–35, viii–ix
- ↵Barkovich AJ. MR and CT evaluation of profound neonatal and infantile asphyxia. AJNR Am J Neuroradiol 1992;13:959–72; discussion 973–75
- ↵Barkovich AJ, Miller SP, Bartha A, et al. MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol 2006;27:533–47
- ↵Barkovich AJ, Hajnal BL, Vigneron D, et al. Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. AJNR Am J Neuroradiol 1998;19:143–49
- ↵Cowan F, Rutherford M, Groenendaal F, et al. Origin and timing of brain lesions in term infants with neonatal encephalopathy. Lancet 2003;361:736–42
- ↵Robertson RL, Ben-Sira L, Barnes PD, et al. MR line-scan diffusion-weighted imaging of term neonates with perinatal brain ischemia. AJNR Am J Neuroradiol 1999;20:1658–70
- ↵Kim DH, Barkovich AJ, Vigneron DB. Short echo time MR spectroscopic imaging for neonatal pediatric imaging. AJNR Am J Neuroradiol 2006;27:1370–72
- ↵Vigneron DB, Barkovich AJ, Noworolski SM, et al. Three-dimensional proton MR spectroscopic imaging of premature and term neonates. AJNR Am J Neuroradiol 2001;22:1424–33
- ↵Ward P, Counsell S, Allsop J, et al. Reduced fractional anisotropy on diffusion tensor magnetic resonance imaging after hypoxic-ischemic encephalopathy. Pediatrics 2006;117:e619–30
- ↵Rutherford M, Counsell S, Allsop J, et al. Diffusion-weighted magnetic resonance imaging in term perinatal brain injury: a comparison with site of lesion and time from birth. Pediatrics 2004;114:1004–14
- Bartha AI, Foster-Barber A, Miller SP, et al. Neonatal encephalopathy: association of cytokines with MR spectroscopy and outcome. Pediatr Res 2004;56:960–66
- Barkovich AJ, Westmark KD, Bedi HS, et al. Proton spectroscopy and diffusion imaging on the first day of life after perinatal asphyxia: preliminary report. AJNR Am J Neuroradiol 2001;22:1786–94
- ↵McKinstry RC, Miller JH, Snyder AZ, et al. A prospective, longitudinal diffusion tensor imaging study of brain injury in newborns. Neurology 2002;59:824–33
- ↵Dumoulin CL, Rohling KW, Piel JE. Magnetic resonance imaging compatible neonate incubator. Concepts Magn Reson B (Magn Reson Eng) 2002;15:117–28
- ↵Partridge SC, Mukherjee P, Henry RG, et al. Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns. Neuroimage 2004;22:1302–14
- Maas LC, Mukherjee P, Carballido-Gamio J, et al. Early laminar organization of the human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants. Neuroimage 2004;22:1134–40
- ↵Deipolyi AR, Mukherjee P, Gill K, et al. Comparing microstructural and macrostructural development of the cerebral cortex in premature newborns: diffusion tensor imaging versus cortical gyration. Neuroimage 2005;27:579–86
- ↵Woods RP, Grafton ST, Holmes CJ, et al. Automated image registration: I. General methods and intrasubject, intramodality validation. J Comput Assist Tomogr 1998;22:139–52
- ↵Woods RP, Grafton ST, Watson JD, et al. Automated image registration: II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr 1998;22:153–65
- ↵Basser PJ, Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson B 1996;111:209–19
- ↵Star-Lack J, Spielman D, Adalsteinsson E, et al. In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors. J Magn Reson 1998;133:243–54
- ↵Hajnal BL, Sahebkar-Moghaddam F, Barnwell AJ, et al. Early prediction of neurologic outcome after perinatal depression. Pediatr Neurol 1999;21:788–93
- ↵Bayley N. The Bayley Scales of Infant Development II. New York: New York Psychological Corporation;1993
- ↵Hermoye L, Saint-Martin C, Cosnard G, et al. Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood. Neuroimage 2006;29:493–504
- ↵Evans AC. The NIH MRI study of normal brain development. Neuroimage 2006;30:184–202
- ↵Miller SP, Ramaswamy V, Michelson D, et al. Patterns of brain injury in term neonatal encephalopathy. J Pediatr 2005;146:453–60
- ↵Mazumdar A, Mukherjee P, Miller JH, et al. Diffusion-weighted imaging of acute corticospinal tract injury preceding wallerian degeneration in the maturing human brain. AJNR Am J Neuroradiol 2003;24:1057–66
- ↵Mukherjee P, McKinstry RC. Diffusion tensor imaging and tractography of human brain development. Neuroimaging Clin N Am 2006;16:19–43, vii.
- ↵Newman TB, Liljestrand P, Jeremy RJ, et al. Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or more. N Engl J Med 2006;354:1889–900
- ↵Wu YW, Liljestrand P, Ferriero DM, et al. Prevalence of motor abnormalities among healthy 5-year-old children. J Pediatric Neurol 2005;3:141–46
- ↵Hack M, Taylor HG, Drotar D, et al. Poor predictive validity of the Bayley Scales of Infant Development for cognitive function of extremely low birth weight children at school age. Pediatrics 2005;116:333–41
- ↵Aylward GP. The conundrum of prediction. Pediatrics 2005;116:491–92
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A.I. Bartha, K.R.L. Yap, S.P. Miller, R.J. Jeremy, M. Nishimoto, D.B. Vigneron, A.J. Barkovich, D.M. Ferriero
The Normal Neonatal Brain: MR Imaging, Diffusion Tensor Imaging, and 3D MR Spectroscopy in Healthy Term Neonates
American Journal of Neuroradiology Jun 2007, 28 (6) 1015-1021; DOI: 10.3174/ajnr.A0521
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The Normal Neonatal Brain: MR Imaging, Diffusion Tensor Imaging, and 3D MR Spectroscopy in Healthy Term Neonates
A.I. Bartha, K.R.L. Yap, S.P. Miller, R.J. Jeremy, M. Nishimoto, D.B. Vigneron, A.J. Barkovich, D.M. Ferriero
American Journal of Neuroradiology Jun 2007, 28 (6) 1015-1021; DOI: 10.3174/ajnr.A0521
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