Article Figures & Data
Figures
- Fig 1.
Patient 3, a 46-year-old man status post 7 months of radiation therapy (72 Gy) for treatment of a squamous cell carcinoma of the left oropharynx, with a nonenhancing ulceration with negative biopsy results (category 1) in the left oropharynx (arrows). This patient has been followed for 11.5 months since initial diagnosis without evidence of tumor recurrence.
- Fig 2.
Patient 5, a 59-year-old woman status post 3.5 months of radiation therapy (60 Gy) for treatment of squamous cell carcinoma of the oral tongue, with a nonenhancing ulceration with negative biopsy results (category 1). This patient has been followed for 16 months since initial diagnosis without evidence of tumor recurrence. A, Contrast-enhanced CT with ulceration in the right lateral part of the oral tongue (arrows). B, PET/CT with 18F-FDG activity (SUV, 12 mg/mL) along the posterior border (arrows) on the ulceration, suspicious for a recurrent tumor.
- Fig 3.
Patient 11, a 75-year-old woman status post 5 months of radiation therapy (70 Gy) for treatment of squamous cell carcinoma of the left oropharyngeal wall, with a nonenhancing ulceration of the left oropharynx (arrow) in which a biopsy was not performed (category 2). This patient has been followed for 30 months since initial diagnosis without evidence of tumor recurrence.
- Fig 4.
Patient 13, a 46-year-old man status post 7 months of radiation therapy (70 Gy) for treatment of a squamous cell carcinoma of the left oropharynx and hypopharynx, with an enhancing ulceration with positive biopsy results (category 3) of the left pyriform sinus. A, Contrast-enhanced CT with an enhancing ulceration of the pyriform sinus (arrows). B, PET/CT with 18F-FDG activity (SUV, 4.6 mg/mL) along the posterior border of the ulceration (arrow).
- Fig 5.
Patient 18, a 70-year-old men status post 61 months of radiation therapy for treatment of a squamous cell carcinoma of the larynx, followed by total laryngectomy with an enhancing ulceration with negative biopsy results (category 4) of the base of the tongue. There is adjacent peripheral and nodular enhancement (arrows). This patient has been followed for 19.5 months since initial diagnosis without evidence of tumor recurrence.
- Fig 6.
Patient 19, a 64-year-old man status post 5 months of radiation therapy (70 Gy) for treatment of a squamous cell carcinoma of the left tonsil, with an enhancing ulceration in the left oropharyngeal wall (arrows) in which biopsy was not performed (category 5). This patient has been followed for 20 months since initial diagnosis without evidence or tumor recurrence.
Tables
Summary of clinical data of patients with soft tissue ulceration
Patient No. Category Age/Sex Rad Dose (Gy) Months After XRT Location of Ulceration Enhancement Biopsy Results 1 1 55/M 66 4.5 Left palatine tonsil None Negative 2 1 53/M 66 8.5 Left palatine tonsil None Negative 3 1 46/M 72 7 Left oropharyngeal wall None Negative 4 1 58/M 70 6.5 Left vocal cords None Negative 5 1 59/F 60 3.5 Right oral tongue None Negative 6 1 50/M OSH 5 Left base of tongue None Negative 7 1 61/F OSH 12 Epiglottis None Negative 8 1 59/M 70 3.5 Epiglottis None Negative 9 1 51/F 70 3 Right base of tongue None Negative 10 2 70/M 60 3.5 Left lateral nasopharynx None N/A 11 2 75/F 70 5 Left oropharyngeal wall None N/A 12 2 64/M 70 5 Right floor of mouth None N/A 13 3 46/M 70 7 Left pyriform sinus Submucosal Positive 14 3 63/F 76 9 Midline oral tongue Submucosal Positive 15 3 70/M 66 6.5 Right oral cavity Nodular Positive 16 3 54/M 66 5 Left palatine tonsil Submucosal Positive 17 4 78/F 72 10.5 Right retromolar trigone Heterogeneous Negative 18 4 70/M OSH 61 Base of tongue Peripheral/Nodular Negative 19 5 64/M 70 5 Left oropharyngeal wall Peripheral N/A 20 5 74/F 70 6 Left oropharynx Peripheral N/A Note:—Rad indicates radiation; OSH, outside hospital; XRT, external beam radiation therapy; N/A, biopsy not performed.
N.B.—Categoric description of ulcerations is author's terminology.
