Research ArticleBrain
A Whole-Brain Analysis in De Novo Parkinson Disease
C. Tessa, M. Giannelli, R. Della Nave, C. Lucetti, C. Berti, A. Ginestroni, U. Bonuccelli and M. Mascalchi
American Journal of Neuroradiology April 2008, 29 (4) 674-680; DOI: https://doi.org/10.3174/ajnr.A0900
C. Tessa
M. Giannelli
R. Della Nave
C. Lucetti
C. Berti
A. Ginestroni
U. Bonuccelli

References
- ↵Braak H, Ghebremedhin E, Rüb U, et al. Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 2004;318:121–34
- ↵Braak H, Rüb U, Jansen Steur EN, et al. Cognitive status correlates with neuropathologic stage in Parkinson disease. Neurology 2005;64:1404–10
- ↵Jankovic J, McDermott M, Carter J, et al. Variable expression of Parkinson's disease: a base-line analysis of the DATATOP cohort—The Parkinson Study Group. Neurology 1990;40:1529–34
- ↵Jankovic J, Kapadia AS. Functional decline in Parkinson disease. Arch Neurol 2001;58:1611–15
- ↵
- ↵Kang GA, Bronstein JM, Masterman DL, et al. Clinical characteristics in early Parkinson's disease in a central California population-based study. Mov Disord 2005;20:1133–42
- ↵Schiess MC, Zheng H, Soukup VM, et al. Parkinson's disease subtypes: clinical classification and ventricular cerebrospinal fluid analysis. Parkinsonism Relat Disord 2000;6:69–76
- ↵Burton EJ, McKeith IG, Burn DJ, et al.. Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls. Brain 2004;127:791–800
- ↵Ramirez-Ruiz B, Marti MJ, Tolosa E, et al. Longitudinal evaluation of cerebral morphological changes in Parkinson's disease with and without dementia. J Neurol 2005;252:1345–52. Epub 2005 Jul 5
- ↵Nagano-Saito A, Washimi Y, Arahata Y, et al. Cerebral atrophy and its relation to cognitive impairment in Parkinson disease. Neurology 2005;64:224–29
- ↵Summerfield C, Junqué C, Tolosa E, et al. Structural brain changes in Parkinson disease with dementia: a voxel-based morphometry study. Arch Neurol 2005;62:281–85
- ↵Beyer MK, Janvin CC, Larses JP, et al. A magnetic resonance imaging study of patients with Parkinson's disease with mild cognitive impairment and dementia using voxel-based morphometry. J Neurol Neurosurg Psychiatry 2007;78:254–59
- ↵Bowen BC, Block RE, Sanchez-Ramos J, et al. Proton MR spectroscopy of the brain in 14 patients with Parkinson disease. AJNR Am J Neuroradiol 1995;16:61–68
- ↵Hu MT, Taylor-Robinson SD, Chaudhuri KR, et al. Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: a proton MR spectroscopy study. J Neurol Neurosurg Psychiatry 1999;67:20–26
- ↵Eidelberg D, Moeller JR, Dhawan V, et al. The metabolic topography of parkinsonism. J Cereb Blood Flow Metab 1994;14:783–801
- Piert M, Koeppe RA, Giordani B, et al. Determination of regional rate constants from dynamic FDG-PET studies in Parkinson's disease. J Nucl Med 1996;37:1115–22
- Bohnen NI, Minoshima S, Giordani B, et al. Motor correlates of occipital glucose hypometabolism in Parkinson's disease without dementia. Neurology 1999;52:541–46
- ↵Hu MT, Taylor-Robinson SD, Chaudhuri KR, et al. Cortical dysfunction in non-demented Parkinson's disease patients: a combined 31P-MRS and 18 FDG-PET study. Brain 2000;123:340–52
- ↵Abe Y, Kachi T, Kato T, et al. Occipital hypoperfusion in Parkinson's disease without dementia: correlation to impaired cortical visual processing. J Neurol Neurosurg Psychiatry 2003;74:419–22
- ↵Oishi N, Udaka F, Kameyama M, et al. Regional cerebral blood flow in Parkinson disease with nonpsychotic visual hallucinations. Neurology 2005;65:1708–15
- ↵Bozzali M, Franceschi M, Falini A, et al. Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI. Neurology 2001;57:1135–37
- ↵Mascalchi M, Lolli F, Della Nave R, et al. Volumetric, diffusion and magnetization transfer MR imaging of the brain in individuals with Huntington's disease. Radiology 2004;232:867–73
- ↵
- ↵Smith SM, Zhang Y, Jenkinson M, et al. Accurate, robust and automated longitudinal and cross-sectional brain changes analysis. Neuroimage 2002;17:479–89
- ↵Gibb WRG, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 1988;51:745–52
- ↵Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinicians. J Psychiatr Res 1975;12:189–98
- ↵Fahn S, Elton RL, and members of the UPDRS development committee. The Unified Idiopathic Parkinson's Disease Rating Scale. In: Fahn S, Marsden CD, Calne D, Goldstein M, eds. Recent Developments in Parkinson's Disease. Vol 2. Florham Park, NJ: Macmillan Healthcare Information;1987 :153–64
- ↵Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967;17:427–42
- ↵Behrens TEJ, Woolrich MW, Jenkinson M, et al. Characterization and propagation of uncertainty in diffusion-weighted MR imaging. Magn Reson Med 2003;50:1077–88
- ↵Smith S, Jenkinson M, Woolrich M, et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004;23:208–19
- ↵Fazekas F, Chawluk JB, Alavi A, et al. MR signal abnormalities at 1.5T in Alzheimer dementia and normal aging. AJNR Am J Neuroradiol 1987;8:421–26
- ↵Della Nave R, Magaudda A, Michelucci R, et al. Whole-brain histogram and voxel-based analyses of apparent diffusion coefficient and magnetization transfer ratio in celiac disease, epilepsy, and cerebral calcifications syndrome. AJNR Am J Neuroradiol 2007;28:479–85
- ↵Zhang Y, Brady M, Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation maximization algorithm. IEEE Trans Med Imaging 2001;20:45–57
- ↵Rorden C, Brett M. Stereotaxic display of brain lesions. Behav Neurol 2000;12:191–200
- ↵Huber JB, Shuttleworth E, Christy JA, et al. Magnetic resonance imaging in dementia of Parkinson's disease. J Neurol Neurosurg Psychiatry 1989;52:1221–27
- ↵Laasko MP, Partanen K, Riekkinen P, et al. Hippocampal volumes in Alzheimer disease, Parkinson's disease with and without dementia, and in vascular dementia: an MRI study. Neurology 1996;46:678–81
- Camicioli R, Moore MM, Kinney A, et al. Parkinson's disease is associated with hippocampal atrophy. Mov Disord 2003;18:784–90
- ↵Tam CW, Burton EJ, McKeith IG, et al. Temporal lobe atrophy on MRI in Parkinson disease with dementia: a comparison with Alzheimer disease and dementia with Lewy bodies. Neurology 2005;8:861–65
- ↵Brück A, Kurki T, Kaasinen V, et al. Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment. J Neurol Neurosurg Psychiatry 2004;75:1467–69
- ↵Hu MT, White SJ, Chaudhuri KR, et al. Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline. J Neural Transm 2001;108:571–78
- ↵
- ↵Seppi K, Schocke MF, Esterhammer R, et al. Diffusion-weighted imaging discriminates progressive supranuclear palsy from PD, but not from the Parkinson variant of multiple system atrophy. Neurology 2003;60:922–27
- Schocke MF, Seppi K, Esterhammer R, et al. Trace of diffusion tensor differentiates the Parkinson variant of multiple system atrophy and Parkinson's disease. Neuroimage 2004;21:1443–51
- Nicoletti G, Lodi R, Condino F, et al. Apparent diffusion coefficient measurements of the middle cerebellar peduncle differentiate the Parkinson's variant of MSA from Parkinson's disease and progressive supranuclear palsy. Brain 2006;129:2679–87
- Paviour DC, Thornton JS, Lees AJ, et al. Diffusion-weighted magnetic resonance imaging differentiates Parkinsonian variant of multiple-system atrophy from progressive supranuclear palsy. Mov Disord 2007;22:68–74
- ↵
- ↵Scherfler C, Schocke MF, Seppi K, et al. Voxel-wise analysis of diffusion-weighted imaging reveals disruption of the olfactory tract in Parkinson's disease. Brain 2006;129:538–42
- ↵Rovaris M, Iannucci G, Sormani MP, et al. Age-related changes in conventional, magnetization transfer and diffusion-tensor MR imaging findings: study with whole-brain tissue histogram analysis. Radiology 2003;227:731–38
- ↵Zivadinov R, Grop A, Sharma J, et al. Reproducibility and accuracy of quantitative magnetic resonance imaging techniques of whole brain atrophy measurements in multiple sclerosis. J Neuroimaging 2005;15:27–36
- ↵Smith SM, Rao A, De Stefano N, et al. Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: cross-validation of BSI, SIENA and SIENAX. Neuroimage 2007;36:1200–06. Epub 2007 Apr 27
- ↵Peters N, Holtmannspotter M, Opherk C, et al. Brain volume changes in CADASIL: a serial MRI study in pure subcortical ischemic vascular disease. Neurology 2006;66:1517–22
- ↵Cercignani M, Inglese M, Pagani E, et al. Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis. AJNR Am J Neuroradiol 2001;22:952–58
- ↵Della Nave R, Foresti S, Pratesi A, et al. Whole-brain histogram and voxel-based analyses of diffusion tensor imaging in patients with leukoaraiois: correlation with motor and cognitive impairment. AJNR Am J Neuroradiol 2007;28:1313–19
- ↵Jellinger KA. Post-mortem studies in Parkinson's disease: is it possible to detect brain areas for specific symptoms? J Neural Transm Suppl 1999;56:1–26
- ↵Jellinger KA. Recent developments in the pathology of Parkinson's disease. J Neural Trans Suppl 2002;62:347–46
- ↵
- ↵Burn DJ, Rowan EN, Allan LM, et al. Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia and dementia with Lewy bodies. J Neurol Neurosurg Psychiatry 2006;77:585–89
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C. Tessa, M. Giannelli, R. Della Nave, C. Lucetti, C. Berti, A. Ginestroni, U. Bonuccelli, M. Mascalchi
A Whole-Brain Analysis in De Novo Parkinson Disease
American Journal of Neuroradiology Apr 2008, 29 (4) 674-680; DOI: 10.3174/ajnr.A0900
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