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Research ArticleNeurointervention

Experimental Study of Intracranial Hematoma Detection with Flat Panel Detector C-Arm CT

H. Arakawa, M.P. Marks, H.M. Do, D.M. Bouley, N. Strobel, T. Moore and R. Fahrig
American Journal of Neuroradiology April 2008, 29 (4) 766-772; DOI: https://doi.org/10.3174/ajnr.A0898
H. Arakawa
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M.P. Marks
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H.M. Do
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D.M. Bouley
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N. Strobel
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T. Moore
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R. Fahrig
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  • Fig 1.
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    Fig 1.

    A DynaCT image of group 1 pig brain (left) shows a prominent high-attenuation mass in brain parenchyma on both sides. Necropsied brain of the same pig (right) confirms the intracranial hematomas in the corresponding area and shape. Air was resorbed in the interval between imaging and necropsy. The bar on the right side bottom indicates 10 mm.

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    Fig 2.

    DynaCT section of pig 3 shows high-attenuation intraventricular hemorrhage casting the lateral ventricles.

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    Fig 3.

    DynaCT image of group 2 pig brain (left) shows a prominent high-attenuation mass in brain parenchyma on the right side. High attenuation in the left brain is the catheter used to create a hematoma; however, no hematoma was seen. Necropsied brain of the same pig (right) confirms the intracranial hematoma in the right brain; no hematoma was confirmed on the left.

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    Fig 4.

    A series of pictures used for area measurement on pigs 6 (upper row) and 7 (lower row). A coronal section of brain images (A and B) obtained with the C-arm CT system shows a high-attenuation mass within brain parenchyma. The high-attenuation areas are polarized and digitally selected as a red mass by ImageJ software (C and D). Coronal sections of brain images obtained with conventional CT (E and F) show intracranial hematoma as a prominent high-attenuation mass. These high-attenuation areas are measured by ImageJ software after polarization (G and H). Harvested necropsied brains reveal intracranial hematoma (I and J). The hematoma areas are measured by ImageJ software with the same technique as used in the measurement of hematoma area of C-arm CT and conventional CT (K and L).

Tables

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    Table 1:

    Summary of injected blood and results of group 1

    Animal No.SideInjected Volume (mL)Hct (%)ACT (Second)Area from FPD (cm2)Area from Necropsy Brain (cm2)Difference (% difference)
    1Rt5241400.790.790.00 (0.0)
    LtNot injected
    2Rt2.5261400.560.520.04 (7.7)
    LtNot injected
    3Rt2.5261130.140.180.04 (22.2)
    Lt*Not injected0.220.200.02 (10.0)
    4Rt2.5191180.220.170.05 (29.4)
    Lt1.520N/A0.310.300.01 (3.3)
    • Note:—Hct indicates hematocrit; ACT, activated clotting time; FPD, flat panel detector; Rt, right; Lt, left; N/A, not available.

    • * Hematoma was formed due to ventricular rupture associated with hematoma creation within the right hemisphere; area measured reflected only the hematoma, not the IVH.

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    Table 2:

    Summary of injected blood and results of group 2

    Animal No.SideInjected Volume (mL)Hct (%)ACT (second)Area from FPD CT (cm2)Area from Necropsy Brain (cm2)Difference (% difference)
    5Rt1021102Nonvis0.46N/A
    Lt522115Nonvis0.41N/A
    6Rt537870.770.710.06 (8.5)
    Lt53170NonvisN/AN/A
    7Rt5291460.550.580.03 (5.2)
    Lt535590.170.130.04 (30.8)
    • Note:—Hct indicates hematocrit; ACT, activated clotting time; FPD, flat panel detector; Nonvis, nonvisible; Rt, right; Lt, left; N/A, not available.

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    Table 3:

    Comparison conventional CT and necropsy hematoma areas

    Animal No.SideInjected Volume (mL)Hct (%)ACT (second)Area from Conventional CT (cm2)Area from Necropsy Brain (cm2)Difference (% difference)
    6Rt537871.331.43*0.10 (7.0)
    Lt53170NonvisN/AN/A
    7Rt5291460.620.58−0.04 (6.9)
    Lt535590.200.13−0.07 (53.8)
    • Note:—Hct indicates hematocrit; ACT, activated clotting time; Nonvis, nonvisible; Rt, right; Lt, left; N/A, not available.

    • * Necropsy area measured for animal 6 differs from the value in Table 2 because a different section was used for the comparison between the conventional pathologic specimen and conventional CT.

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American Journal of Neuroradiology: 29 (4)
American Journal of Neuroradiology
Vol. 29, Issue 4
April 2008
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Cite this article
H. Arakawa, M.P. Marks, H.M. Do, D.M. Bouley, N. Strobel, T. Moore, R. Fahrig
Experimental Study of Intracranial Hematoma Detection with Flat Panel Detector C-Arm CT
American Journal of Neuroradiology Apr 2008, 29 (4) 766-772; DOI: 10.3174/ajnr.A0898

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Experimental Study of Intracranial Hematoma Detection with Flat Panel Detector C-Arm CT
H. Arakawa, M.P. Marks, H.M. Do, D.M. Bouley, N. Strobel, T. Moore, R. Fahrig
American Journal of Neuroradiology Apr 2008, 29 (4) 766-772; DOI: 10.3174/ajnr.A0898
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