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Research ArticlePediatric Neuroimaging

PHACES Association: A Neuroradiologic Review of 17 Patients

V.S. Oza, E. Wang, A. Berenstein, M. Waner, D. Lefton, J. Wells and F. Blei
American Journal of Neuroradiology April 2008, 29 (4) 807-813; DOI: https://doi.org/10.3174/ajnr.A0937
V.S. Oza
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E. Wang
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A. Berenstein
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M. Waner
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D. Lefton
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J. Wells
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F. Blei
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    Fig 1.

    A, Eight initial embryonic developmental patterns are identified. B, Final segmental patterns are extracted from image analysis: S1 (frontotemporal), S2 (maxillary), S3 (mandibular), S4 (frontonasal). Reproduced with permission from J Pediatr 139:117-23, copyright 2001 by the AAP.

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    Fig 2.

    A, Color photograph of patient 10, illustrating a hemangioma in an S3 distribution. Note additional thoracic and supraumbilical raphe. B, Color photograph of patient 1 with S1-S4 cutaneous distribution.

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    Fig 3.

    A, Axial T1-weighted image of the brain demonstrates decreased size of the left hemisphere and abnormally thickened left frontoparietal cortex (arrowheads). Also demonstrated is an abnormal pattern of sulcation with thickened gyri. B, Coronal T2-weighted image of the brain demonstrates prominent thickening of the left temporoparietal cortex with poor gray-white discrimination. Well-defined gray-white differentiation on the right (arrows) is marked for normal comparison.

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    Fig 4.

    A, Coronal maximum-intensity-projection reconstruction from intracranial time-of-flight MRA demonstrates an ectatic and tortuous appearance of the left precavernous and cavernous ICA (arrow). B, 3D MRA rendering from NOVA with flow measurement through the cervical left ICA. The left ICA at the skull base is markedly irregular and tortuous.

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    Fig 5.

    Postcontrast coronal T1-weighted image of the brain again demonstrates the abnormally enhancing mass (arrow) just below right-sided portions of the hypothalamus. Vague surface enhancement along the right temporal lobe is noted (arrowheads).

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American Journal of Neuroradiology: 29 (4)
American Journal of Neuroradiology
Vol. 29, Issue 4
April 2008
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Cite this article
V.S. Oza, E. Wang, A. Berenstein, M. Waner, D. Lefton, J. Wells, F. Blei
PHACES Association: A Neuroradiologic Review of 17 Patients
American Journal of Neuroradiology Apr 2008, 29 (4) 807-813; DOI: 10.3174/ajnr.A0937

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PHACES Association: A Neuroradiologic Review of 17 Patients
V.S. Oza, E. Wang, A. Berenstein, M. Waner, D. Lefton, J. Wells, F. Blei
American Journal of Neuroradiology Apr 2008, 29 (4) 807-813; DOI: 10.3174/ajnr.A0937
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  • Heterogeneous Continuum of Cerebral and Cervicofacial Venous Malformations
  • Localized Marked Elongation of the Distal Internal Carotid Artery with or without PHACE Syndrome: Segmental Dolichoectasia of the Distal Internal Carotid Artery
  • Teaching NeuroImages: A cutaneous vascular malformation hides giant cerebral aneurysms
  • Asymmetric Meckel Cave Enlargement: A Potential Marker of PHACES Syndrome
  • Enlargement of the Internal Auditory Canal and Associated Posterior Fossa Anomalies in PHACES Association
  • Cervical and Intracranial Arterial Anomalies in 70 Patients with PHACE Syndrome
  • Infantile Hemangiomas Involving the Neuraxis: Clinical and Imaging Findings
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This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

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