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Research ArticleNeurointervention

Stability of Intracranial Aneurysms Adequately Occluded 6 Months after Coiling: A 3T MR Angiography Multicenter Long-Term Follow-Up Study

M.E. Sprengers, J. Schaafsma, W.J. van Rooij, M. Sluzewski, G.J.E. Rinkel, B.K. Velthuis, J.C. van Rijn and C.B. Majoie
American Journal of Neuroradiology October 2008, 29 (9) 1768-1774; DOI: https://doi.org/10.3174/ajnr.A1181
M.E. Sprengers
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J. Schaafsma
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W.J. van Rooij
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M. Sluzewski
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G.J.E. Rinkel
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B.K. Velthuis
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J.C. van Rijn
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C.B. Majoie
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    Fig 1.

    Flow chart of total cohort and included aneurysms.

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    Fig 2.

    A 61-year-old woman with a ruptured 3-mm middle cerebral artery aneurysm. A, Precoiling angiogram shows a small aneurysm. B, Complete occlusion after coiling. C, Stable complete occlusion at 6 months. D, MRA at 7.3 years demonstrates a 1 × 2 mm intraluminal opening inside the coil mesh classified as a recurrence (arrow).

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    Fig 3.

    A 54-year-old woman with a ruptured 5-mm basilar tip aneurysm. A, Precoiling vertebral angiogram shows a basilar tip aneurysm. B, Stable complete occlusion at 6 months. C, Angiogram at 5.8 years shows a 2 × 3 mm disklike recurrence at the base of the aneurysm. D, MRA at 8.0 years is unchanged, compared with the last angiogram.

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    Fig 4.

    A 49-year-old woman with a ruptured 10-mm basilar tip aneurysm. A, Precoiling vertebral angiogram demonstrates the basilar tip aneurysm with a small bleb on its base (arrow). B, On the angiogram immediately postcoiling, the bleb (arrow) is not occluded. C, Unchanged open bleb (arrow) at 6 months. D, Angiogram at 5.5 years with recurrence (arrow) at the base from the bleb. E and F, MRA overview (E) and detail (F) at 8.1 years demonstrate unchanged recurrence (arrow).

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    Fig 5.

    A 66-year-old man presenting with seizures with an unruptured left middle cerebral artery aneurysm. A, Precoiling angiogram. B, Complete occlusion after coiling. C, Stable complete occlusion at 6 months. D, MRA at 6.6 years shows a 6 × 4 mm recurrence (arrow). E, Angiogram before the second coiling. F, After the second coiling, again complete occlusion is seen. G, Six months after the second coiling, repeat reopening of the aneurysm is noted. H, After the third coiling, again complete occlusion is seen. Note that the coil mesh is much larger than the aneurysmal lumen in A. I, Initial CT angiography before the first coiling demonstrates thrombus surrounding the aneurysm lumen and perifocal edema. J, MR imaging at 6.6 years shows migration of the coil mesh in the thrombosed part of aneurysm and a perianeurysmal cyst.

Tables

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    Table 1:

    Patient and aneurysm characteristics

    Characteristics457 Patients with 497 Aneurysms with 6-Month Angiographic Follow-Up297 Patients with 316 Aneurysms with Adequate Occlusion at 6 Months36 Patients Fulfilling Inclusion Criteria Not Participating in the Study104 Patients with 111 Aneurysms with Long-Term MRA Follow-Up
    Women311 (68%)206 (69%)22 (61%)71 (69%)
    Mean age (yr)(median, 51; range, 18–82)52.0 (median, 51; range, 26–82)56.0 (median, 55; range, 36–69)54.7 (median, 54; range, 39–70)
    Ruptured aneurysms351 (77%)216 (72%)30 (83%)84 (81%)
    Aneurysm size (mm)2–55 (mean, 9.2; median, 7)2–22 (mean, 7.4; median, 6)3–15 (mean, 7.4; median, 7)3–17 (mean, 6.6; median, 5)
    Aneurysm location
    ACA137 (27.6%)86 (27.2%)8 (22.2%)23 (20.7%)
    MCA34 (6.8%)20 (6.3%)1 (2.7%)11 (9.9%)
    Posterior circulation167 (33.6%)107 (33.9%)10 (27.7%)46 (41.5)
    ICA159 (32%)103 (32.6%)17 (47.2%)31 (27.9%)
    • Note:—ACA indicates anterior cerebral artery; MCA, middle cerebral artery; ICA, internal carotid artery.

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    Table 2:

    Detailed characteristics of 104 patients with 111 aneurysms with long-term MRA follow-up

    Characteristics
    Patient
        Women71 (69 %)
        Mean age (yr)54.7 (median, 54; range, 39–70)
    Aneurysm
        Ruptured84 (81 %)
        Mean size (mm)6.6 (median, 5; range, 3–17)
        ≤5 mm42 (46.9%)
        6–10 mm40 (36.1%)
        ≥10 mm19 (17 %)
    Aneurysm location
        Anterior circulation65 (58.5%)
        Pericallosal artery3
        Anterior communicating artery18
        A12
        Middle cerebral artery11
        Supraclinoid internal carotid artery7
        Anterior choroidal artery4
        Posterior communicating artery14
        Carotid ophthalmic artery6
    Posterior circulation46 (41.5%)
        Basilar tip24
        Posterior inferior cerebellar artery10
        Superior cerebellar artery7
        Posterior cerebral artery4
        Basilar trunk1
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American Journal of Neuroradiology: 29 (9)
American Journal of Neuroradiology
Vol. 29, Issue 9
October 2008
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M.E. Sprengers, J. Schaafsma, W.J. van Rooij, M. Sluzewski, G.J.E. Rinkel, B.K. Velthuis, J.C. van Rijn, C.B. Majoie
Stability of Intracranial Aneurysms Adequately Occluded 6 Months after Coiling: A 3T MR Angiography Multicenter Long-Term Follow-Up Study
American Journal of Neuroradiology Oct 2008, 29 (9) 1768-1774; DOI: 10.3174/ajnr.A1181

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Stability of Intracranial Aneurysms Adequately Occluded 6 Months after Coiling: A 3T MR Angiography Multicenter Long-Term Follow-Up Study
M.E. Sprengers, J. Schaafsma, W.J. van Rooij, M. Sluzewski, G.J.E. Rinkel, B.K. Velthuis, J.C. van Rijn, C.B. Majoie
American Journal of Neuroradiology Oct 2008, 29 (9) 1768-1774; DOI: 10.3174/ajnr.A1181
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Cited By...

  • Inter- and Intrarater Agreement on the Outcome of Endovascular Treatment of Aneurysms Using MRA
  • Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years
  • Is Visual Evaluation of Aneurysm Coiling a Reliable Study End Point?: Systematic Review and Meta-Analysis
  • Is long-term follow-up of adequately coil-occluded ruptured cerebral aneurysms always necessary? A single-center study of recurrences after endovascular treatment
  • Outcomes of Endovascular Treatments of Aneurysms: Observer Variability and Implications for Interpreting Case Series and Planning Randomized Trials
  • An approach to recurrent aneurysms following endovascular coiling
  • Late Reopening of Adequately Coiled Intracranial Aneurysms: Frequency and Risk Factors in 400 Patients With 440 Aneurysms
  • Cost-Effectiveness of Magnetic Resonance Angiography Versus Intra-arterial Digital Subtraction Angiography to Follow-Up Patients With Coiled Intracranial Aneurysms
  • Late Adverse Events in Coiled Ruptured Aneurysms with Incomplete Occlusion at 6-Month Angiographic Follow-Up
  • Long-Term Follow-Up of 1036 Cerebral Aneurysms Treated by Bare Coils: A Multicentric Cohort Treated between 1998 and 2003
  • Opinion: Imaging Follow-Up after Coiling of Intracranial Aneurysms
  • Counterpoint: Has the Last Word Been Said?
  • Long-Term Recurrent Subarachnoid Hemorrhage After Adequate Coiling Versus Clipping of Ruptured Intracranial Aneurysms
  • MR Angiography Follow-Up 5 Years after Coiling: Frequency of New Aneurysms and Enlargement of Untreated Aneurysms
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