Research ArticlePEDIATRICS
Whole-Brain Voxel-Based Morphometry in Kallmann Syndrome Associated with Mirror Movements
M. Koenigkam-Santos, A.C. Santos, T. Borduqui, B.R. Versiani, J.E.C. Hallak, J.A.S. Crippa and M. Castro
American Journal of Neuroradiology October 2008, 29 (9) 1799-1804; DOI: https://doi.org/10.3174/ajnr.A1202
M. Koenigkam-Santos
A.C. Santos
T. Borduqui
B.R. Versiani
J.E.C. Hallak
J.A.S. Crippa

References
- ↵Seminara SB, Hayes FJ, Crowley WF Jr, et al. Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev 1998;19:521–39
- ↵Schwanzel-Fukuda M, Bick D, Pfaff DW. Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome. Brain Res Mol Brain Res 1989;6:311–26
- ↵Hayes FJ, Seminara SB, Crowley WF Jr. Hypogonadotropic hypogonadism. Endocrinol Metab Clin North Am 1998;27:739–63, vii
- ↵Franco B, Guioli S, Pragliola A, et al. A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules. Nature 1991;353:529–36
- ↵Pitteloud N, Acierno JS Jr, Meysing A, et al. Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci U S A 2006;103:6281–86. Epub 2006 Apr 10
- ↵Matsumoto S, Yamazaki C, Masumoto KH, et al. Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A 2006;103:4140–45. Epub 2006 Mar 2
- ↵
- ↵Sato N, Katsumata N, Kagami M, et al. Clinical assessment and mutation analysis of Kallmann syndrome 1 (KAL1) and fibroblast growth factor receptor 1 (FGFR1, or KAL2) in five families and 18 sporadic patients. J Clin Endocrinol Metab 2004;89:1079–88
- ↵
- ↵Connolly K, Stratton P. Developmental changes in associated movements. Dev Med Child Neurol 1968;10:49–56
- ↵Mayston MJ, Harrison LM, Stephens JA. A neurophysiological study of mirror movements in adults and children. Ann Neurol 1999;45:583–94
- ↵Nass R. Mirror movement asymmetries in congenital hemiparesis: the inhibition hypothesis revisited. Neurology 1985;35:1059–62
- ↵Mayston MJ, Harrison LM, Quinton R, et al. Mirror movements in X-linked Kallmann's syndrome. I. A neurophysiological study. Brain 1997;120 (Pt 7):1199–216
- ↵Krams M, Quinton R, Mayston MJ, et al. Mirror movements in X-linked Kallmann's syndrome. II. A PET study. Brain 1997;120 (Pt 7):1217–28
- ↵Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000;11:805–21
- ↵Ashburner J, Friston KJ. Why voxel-based morphometry should be used. Neuroimage 2001;14:1238–43
- ↵Kubicki M, Shenton ME, Salisbury DF, et al. Voxel-based morphometric analysis of gray matter in first episode schizophrenia. Neuroimage 2002;17:1711–19
- Karas GB, Burton EJ, Rombouts SA, et al. A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry. Neuroimage 2003;18:895–907
- Bernasconi N, Duchesne S, Janke A, et al. Whole-brain voxel-based statistical analysis of gray matter and white matter in temporal lobe epilepsy. Neuroimage 2004;23:717–23
- ↵Good CD, Johnsrude IS, Ashburner J, et al. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001;14 (1 Pt 1):21–36
- ↵McMillan AB, Hermann BP, Johnson SC, et al. Voxel-based morphometry of unilateral temporal lobe epilepsy reveals abnormalities in cerebral white matter. Neuroimage 2004;23:167–74
- ↵Krams M, Quinton R, Ashburner J, et al. Kallmann's syndrome: mirror movements associated with bilateral corticospinal tract hypertrophy. Neurology 1999;52:816–22
- ↵Doty RL, Shaman P, Dann M. Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function. Physiol Behav 1984;32:489–502
- ↵Blackwood DH, Glabus MF, Dunan J, et al. Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia: Correlations with memory and P300. Br J Psychiatry 1999;175:357–66
- ↵Rusch N, van Elst LT, Ludaescher P, et al. A voxel-based morphometric MRI study in female patients with borderline personality disorder. Neuroimage 2003;20:385–92
- ↵Trarbach EB, Costa EM, Versiani B, et al. Novel fibroblast growth factor receptor 1 mutations in patients with congenital hypogonadotropic hypogonadism with and without anosmia. J Clin Endocrinol Metab 2006;91:4006–12
- ↵Vogl TJ, Stemmler J, Heye B, et al. Kallman syndrome versus idiopathic hypogonadotropic hypogonadism at MR imaging. Radiology 1994;191:53–57
- ↵Quinton R, Duke VM, de Zoysa PA, et al. The neuroradiology of Kallmann's syndrome: a genotypic and phenotypic analysis. J Clin Endocrinol Metab 1996;81:3010–17
- ↵Madan R, Sawlani V, Gupta S, et al. MRI findings in Kallmann syndrome. Neurol India 2004;52:501–03
- ↵
- ↵Dennis M. Impaired sensory and motor differentiation with corpus callosum agenesis: a lack of callosal inhibition during ontogeny? Neuropsychologia 1976;14:455–69
- ↵Leinsinger GL, Heiss DT, Jassoy AG, et al. Persistent mirror movements: functional MR imaging of the hand motor cortex. Radiology 1997;203:545–52
- ↵Mayer M, Schulze S, Danek A, et al. Dipole source analysis in persistent mirror movements. Brain Topogr 1999;12:49–60
- ↵Kim YH, Jang SH, Chang Y, et al. Bilateral primary sensori-motor cortex activation of post-stroke mirror movements: an fMRI study. Neuroreport 2003;14:1329–32
- Li JY, Espay AJ, Gunraj CA, et al. Interhemispheric and ipsilateral connections in Parkinson's disease: relation to mirror movements. Mov Disord 2007;22:813–21
- ↵Verstynen T, Spencer R, Stinear CM, et al. Ipsilateral corticospinal projections do not predict congenital mirror movements: a case report. Neuropsychologia 2007;45:844–52
- ↵Kallmann FJ, Schonfeld WA, Barvera SE. The genetic aspects of primary eunuchoidism. Am J Ment Defic 1944;48:203–36
- ↵Obaydi H, Izmeth MG, Rigby JC. Kallmann's syndrome and mental handicap. J Intellect Disabil Res 1992;36 (Pt 5):457–60
- ↵
- ↵Pitteloud N, Quinton R, Pearce S, et al. Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism. J Clin Invest 2007;117:457–63
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M. Koenigkam-Santos, A.C. Santos, T. Borduqui, B.R. Versiani, J.E.C. Hallak, J.A.S. Crippa, M. Castro
Whole-Brain Voxel-Based Morphometry in Kallmann Syndrome Associated with Mirror Movements
American Journal of Neuroradiology Oct 2008, 29 (9) 1799-1804; DOI: 10.3174/ajnr.A1202
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