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Research ArticleBrain

Comparison of Eye Lens Dose on Neuroimaging Protocols between 16- and 64-Section Multidetector CT: Achieving the Lowest Possible Dose

J.S.P. Tan, K.-L. Tan, J.C.L. Lee, C.-M. Wan, J.-L. Leong and L.-L. Chan
American Journal of Neuroradiology February 2009, 30 (2) 373-377; DOI: https://doi.org/10.3174/ajnr.A1327
J.S.P. Tan
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K.-L. Tan
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J.C.L. Lee
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C.-M. Wan
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J.-L. Leong
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L.-L. Chan
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    Fig 1.

    Graphic comparison of mean eye lens dose between 16-section and 64-section MDCT for the neuroimaging CT protocols studied.

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    Fig 2.

    A, Photograph of a volunteer; B, sagittal scout image with section lines of a patient in the chin tuck position during a CT brain scanning on a 64-section MDCT to remove the eyes from the radiation beam. C, Sagittal scout image with section lines for a CT brain scanning in a tilted axial mode on the 16-section MDCT for comparison.

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    Table 1:

    Standard clinical head and neck CT protocols used with the CT parameters

    CT Protocol*MDCT†CARE Dose‡Set mAsEffective mAsTube Voltage (kV)Section Collimation (mm)Beam Width (mm)Rotation Time (s)KernelPitchNo.
    Brain (tilted axial mode)16+4003601205121.0B31f/cerebrumNA1
    –400NA1205121.0B31f/cerebrumNA2
    Brain (helical mode)16+4003941200.75120.75B31f/cerebrum0.63
    –400NA1200.75120.75B31f/cerebrum0.64
    64+4002661200.619.21.0B31f/cerebrum0.85
    –400NA1200.619.21.0B31f/cerebrum0.86
    Paranasal sinus navigation16+2001891200.75120.75B70fSharp/bone0.67
    64+2001321200.619.21.0B70fSharp/bone0.98
    Temporal bone/orbits16+4003851200.69.60.75B70fSharp/bone0.69
    64+4003551200.619.215B70fSharp/bone0.810
    • Note:—MDCT indicates multidetector CI; NA, not applicable.

    • * Coverage for CT orbits is similar to that of a CT temporal bone, but a different CT kernel is used.

    • † 16 MDCT refers to 16-section MDCT scanner and 64 MDCT refers to 64-section MDCT scanner.

    • ‡ CARE dose + indicates that the ATCM program is on; CARE dose − indicates that the program is off.

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    Table 2:

    Average eye lens dose for each imaging protocol with CTDIvol and DLP measurements*

    CT ProtocolMDCTCARE DoseCTDIvol (mGy) (mean ± SD)DLP (mGy.cm) (mean ± SD)Eye Lens Dose (mGy) (mean ± SD)PValueNo.
    Brain (tilted axial mode)16+63.36 ± 2.18 (60.48, 65.86)930.50 ± 61.08 (847.00, 988.00)15.56 ± 4.18 (10.20, 22.50)NS (.183)1
    –67.20 ± 0 (67.20, 67.20)985.67 ± 32.26 (941.00, 1008.00)18.14 ± 7.59 (10.60, 36.00)2
    Brain (helical mode)16+83.44 ± 0.42 (83.15, 84.02)1421.33 ± 94.54 (1301.00, 1512.00)82.16 ± 13.43 (56.50, 97.90)NS (.096)3
    –84.30 ± 0 (84.30, 84.30)1449.67 ± 94.43 (1319, 1517)88.83 ± 13.47 (65.30, 102.60)4
    64+36.77 ± 1.76 (35.31, 39.34)601.33 ± 47.48 (559, 669)47.18 ± 5.99 (36.2, 60.0)<.0005
    –53.33 ± 0.06 (53.30, 53.46)870.83 ± 32.00 (831, 909)63.90 ± 7.74 (49.10, 75.90)6
    Paranasal sinus navigation16+40.57 ± 0.66 (39.42, 41.14)563.67 ± 28.24 (524, 595)45.90 ± 2.65 (40.3, 50.00)<.0007
    64+20.69 ± 0.77 (19.96, 21.82)301.83 ± 7.11 (289, 310)28.96 ± 3.35 (22.80, 35.30)8
    Temporal bone/orbits16+102.86 ± 7.08 (92.71, 109.31)483.33 ± 48.84 (424, 541)98.58 ± 9.03 (83.00, 111.7)<.0009
    64+46.71 ± 2.07 (43.88, 48.59)298.50 ± 20.97 (270, 318)53.57 ± 10.07 (39.10, 70.50)10
    • Note:—NS indicates not significant; CTDIvol, volume CT dose index; DLP, dose-length product.

    • * The CTDIvol, DLP, and eye lens doses are tabulated as mean ± SD with the minimum and maximum values in parentheses. Comparison was made between protocols using the paired Student t test, and statistical significance was defined at P < .05.

    • View popup
    Table 3:

    Comparison of eye lens dose savings on CT brain protocols using ATCM between titled axial-versus-helical modes and 16-section-versus-64-section MDCT

    CT Brain Protocol*MDCTCARE DoseMean Eye Lens Dose (mGy)Dose Savings (%) (P value)Protocol No.
    Tilted axial16+15.5681.1 (.000)1
    Helical82.163
    Tilted axial16+15.5667.0 (.000)1
    Helical6447.185
    Helical16+82.1642.6 (.000)3
    6447.185
    • Note:—ATCM indicates automatic tube current modulation.

    • * Comparison was made between protocols using the paired Student t test, and statistical significance was defined at P < .05.

    • View popup
    Table 4:

    Comparison of CTDIvol and DLP values between cadaveric cases and clinical scans*

    CT ProtocolMDCTCARE DoseCadaveric CasesClinical Cases
    CTDIvol (mGy) (mean ± SD)DLP (mGy.cm) (mean ± SD)CTDIvol (mGy) (mean ± SD)DLP (mGy.cm) (mean ± SD)
    Brain (tilted axial mode)16+63.36 ± 2.18930.50 ± 61.0859.56 ± 2.25857.00 ± 24.49
    Brain (helical mode)64+36.77 ± 1.76601.33 ± 47.4839.43 ± 1.30711.67 ± 35.43
    Paranasal sinus navigation16+40.57 ± 0.66563.67 ± 28.2440.19 ± 1.01587.17 ± 60.49
    64+20.69 ± 0.77301.83 ± 7.1123.37 ± 1.19334.33 ± 28.79
    Temporal bone/orbits16+102.86 ± 7.08483.33 ± 48.84104.45 ± 6.78648.17 ± 132.09
    64+46.71 ± 2.07298.50 ± 20.9758.34 ± 7.08487.00 ± 84.38
    • * Clinical scanning is routinely performed with ATCM. The CTDIvol and DLP values for clinical brain scans acquired in the helical mode on the 16-section MDCT are not available for comparison. This is because the protocol is only used in the rare clinical situation when the tilted axial mode cannot be executed (eg, patients in a cervical collar).

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American Journal of Neuroradiology: 30 (2)
American Journal of Neuroradiology
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February 2009
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J.S.P. Tan, K.-L. Tan, J.C.L. Lee, C.-M. Wan, J.-L. Leong, L.-L. Chan
Comparison of Eye Lens Dose on Neuroimaging Protocols between 16- and 64-Section Multidetector CT: Achieving the Lowest Possible Dose
American Journal of Neuroradiology Feb 2009, 30 (2) 373-377; DOI: 10.3174/ajnr.A1327

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Comparison of Eye Lens Dose on Neuroimaging Protocols between 16- and 64-Section Multidetector CT: Achieving the Lowest Possible Dose
J.S.P. Tan, K.-L. Tan, J.C.L. Lee, C.-M. Wan, J.-L. Leong, L.-L. Chan
American Journal of Neuroradiology Feb 2009, 30 (2) 373-377; DOI: 10.3174/ajnr.A1327
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