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EditorialEDITORIALS

Tissue-Specific MR Imaging in Multiple Sclerosis

À. Rovira
American Journal of Neuroradiology August 2009, 30 (7) 1277-1278; DOI: https://doi.org/10.3174/ajnr.A1777
À. Rovira
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References

  1. ↵
    Sormani MP, Bonzano L, Roccatagliata L, et al. Magnetic resonance imaging as a potential surrogate for relapse in multiple sclerosis: a meta-analytic approach. Ann Neurol 2009;65:270–77
  2. ↵
    Goodin DS. Magnetic resonance imaging as a surrogate outcome measure of disability in multiple sclerosis: have we been overly harsh in our assessment? Ann Neurol 2006;59:597–05
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  3. ↵
    Barkhof F. The clinico-radiological paradox in multiple sclerosis revisited. Curr Opin Neurol 2002;15:239–45
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    Barkhof F, Bruck W, De Groot CJ, et al. Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch Neurol 2003;60:1073–81
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    Arnold DL. Evidence for neuroprotection and remyelination using imaging techniques. Neurology 2007;68 (suppl 3):S83–S90
    Abstract/FREE Full Text
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    Van Walderveen MA, Barkhoff F, Hommes OR, et al. Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images. Neurology 1995;45:1684–90
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    Bagnato F, Jeffries N, Richert ND, et al. Evolution of T1 black holes in patients with multiple sclerosis imaged monthly for 4 years. Brain. 2003;126 (Pt 8):1782–89
    Abstract/FREE Full Text
  8. ↵
    Zivadinov R. Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis? Neurology 2007;68 (suppl 3):S72–S82
    Abstract/FREE Full Text
  9. ↵
    Filippi M, Rovaris M, Rocca MA, et al, and the European/Canadian Glatiramer Acetate Study Group. Glatiramer acetate reduces the proportion of new MS lesions evolving into “black holes.” Neurology 2001;57:731–33
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  10. Dalton CM, Miszkiel KA, Barker GJ, et al. Effect of natalizumab on conversion of gadolinium enhancing lesions to T1 hypointense lesions in relapsing multiple sclerosis. J Neurol 2004;251:407–13
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    Bagnato F, Gupta S, Richert ND, et al. Effects of interferon beta-1b on black holes in multiple sclerosis over a 6-year period with monthly evaluations. Arch Neurol 2005;62:1684–88
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    Van Walderveen MA, Kamphorst W, Scheltens P, et al. Histopathologic correlates of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis. Neurology 1998;50:1282–88
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    Li BS, Moriarty DM, Regal J, et al. In vivo 3D 1H MRS of T1-hypointense lesions in relapsing-remitting multiple sclerosis. In: Proceedings of the International Society for Magnetic Resonance in Medicine, Glasgow, Scotland, UK, April 21–27,2001
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    Barkhof F, Karas GB, van Walderveen MA. T1 hypointensities and axonal loss. Neuroimaging Clin N Am 2000;10:739–52
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    Fritz D, Dwyer MG, Quadros C, et al. T1 intensity differences to normal appearing white matter in hypointense lesions on MRI are related to clinical status in multiple sclerosis. J Neurol 2006;253:104–26
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    Riva M, Ikonomidou VN, Ostuni JJ, et al. Tissue-specific imaging as a robust methodology to differentiate in vivo T1 black holes with advanced multiple sclerosis-induced damage. AJNR Am J Neuroradiol 2009;30:1394–401
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    Miller DH. Biomarkers and surrogate outcomes in neurodegenerative disease: lessons from multiple sclerosis. NeuroRx 2004;1:284–94
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    Rice C, Scolding N. Strategies for achieving and monitoring myelin repair. J Neurol 2007;254:275–83
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American Journal of Neuroradiology: 30 (7)
American Journal of Neuroradiology
Vol. 30, Issue 7
August 2009
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À. Rovira
Tissue-Specific MR Imaging in Multiple Sclerosis
American Journal of Neuroradiology Aug 2009, 30 (7) 1277-1278; DOI: 10.3174/ajnr.A1777

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Tissue-Specific MR Imaging in Multiple Sclerosis
À. Rovira
American Journal of Neuroradiology Aug 2009, 30 (7) 1277-1278; DOI: 10.3174/ajnr.A1777
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