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Research ArticleFunctional
Open Access

Intelligence and Medial Temporal Lobe Function in Older Adults: A Functional MR Imaging–Based Investigation

D.M. Yousem, M.A. Yassa, C. Cristinzio, I. Kusevic, M. Mohamed, B.S. Caffo and S.S. Bassett
American Journal of Neuroradiology September 2009, 30 (8) 1477-1481; DOI: https://doi.org/10.3174/ajnr.A1634
D.M. Yousem
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M.A. Yassa
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C. Cristinzio
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I. Kusevic
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M. Mohamed
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B.S. Caffo
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S.S. Bassett
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References

  1. 1.↵
    1. Larson GE,
    2. Haier RJ,
    3. LaCasse L,
    4. et al
    . Evaluation of a “mental effort” hypothesis for correlations between cortical metabolism and intelligence. Intelligence 1995; 21: 267– 78
    CrossRefWeb of Science
  2. 2.↵
    1. Duncan J,
    2. Seitz RJ,
    3. Kolodny J,
    4. et al
    . A neural basis for general intelligence. Science 2000; 289: 457– 60
    Abstract/FREE Full Text
  3. 3.↵
    1. Neubauer AC,
    2. Fink A,
    3. Schrausser DG
    . Intelligence and neural efficiency: the influence of task content and sex on the brain-IQ relationship. Intelligence 2002; 30: 515– 36
  4. 4.↵
    1. Gray JR,
    2. Chabris CF,
    3. Braver TS
    . Neural mechanisms of general fluid intelligence. Nat Neurosci 2003; 6: 316– 22
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Haier RJ,
    2. White NS,
    3. Alkire MT
    . Individual differences in general intelligence correlate with brain function during nonreasoning tasks. Intelligence 2003; 31: 429– 41
    CrossRefWeb of Science
  6. 6.↵
    1. Flashman LA,
    2. Andreasen NC,
    3. Flaum M,
    4. et al
    . Intelligence and regional brain volumes in normal controls. Intelligence 1997; 25: 149– 60
    CrossRefWeb of Science
  7. 7.↵
    1. Haier RJ,
    2. Jung RE,
    3. Yeo RA,
    4. et al
    . Structural brain variation and general intelligence. Neuroimage 2004; 23: 425– 33
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Eichenbaum H
    . A cortical-hippocampal system for declarative memory. Nat Rev Neurosci 2000; 1: 41– 50
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Rapport LJ,
    2. Axelrod BN,
    3. Theisen ME,
    4. et al
    . Relationship of IQ to verbal learning and memory: test and retest. J Clin Exp Neuropsychol 1997; 19: 655– 66
    PubMedWeb of Science
  10. 10.↵
    1. Steinberg BA,
    2. Bieliauskas LA,
    3. Smith GE,
    4. et al
    . Mayo's Older Americans Normative Studies: Age- and IQ-adjusted norms for the Wechsler Memory Scale–Revised. Clin Neuropsychol 2005; 19: 378– 463
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Steinberg BA,
    2. Bieliauskas LA,
    3. Smith GE,
    4. et al
    . Mayo's Older Americans Normative Studies: Age- and IQ-adjusted norms for the Auditory Verbal Learning Test and the Visual Spatial Learning Test. Clin Neuropsychol 2005; 19: 464– 523
    PubMed
  12. 11.↵
    1. Grant I,
    2. Adams K
    1. Heaton R K,
    2. Grant I,
    3. Matthews C.
    . Grant I, Adams K. Differences in neuropsychological test performance associated with age, education and sex. Neuropsychological Assessment of Neuropsychiatric Disorders. 1986New York: Oxford University Press;
  13. 13.↵
    1. McCurry SM,
    2. Edland SD,
    3. Teri L,
    4. et al
    . The cognitive abilities screening instrument (CASI): data from a cohort of 2524 cognitively intact elderly. Int J Geriatr Psychiatry 1999; 14: 882– 88
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Crum RM,
    2. Anthony JC,
    3. Bassett SS,
    4. et al
    . Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA 1993; 269: 2386– 91
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Schmidt R,
    2. Freidl W,
    3. Fazekas F,
    4. et al
    . The Mattis-Dementia-Rating-Scale: normative data from 1,001 healthy volunteers. Neurology 1994; 44: 964– 66
    Abstract/FREE Full Text
  16. 16.↵
    1. Springer MV,
    2. McIntosh AR,
    3. Winocur G,
    4. et al
    . The relation between brain activity during memory tasks and years of education in young and older adults. Neuropsychology 2005; 19: 181– 92
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Coffey CE,
    2. Saxton JA,
    3. Ratcliff G,
    4. et al
    . Relation of education to brain size in normal aging: implications for the reserve hypothesis. Neurology 1999; 53: 189– 96
    Abstract/FREE Full Text
  18. 18.↵
    1. Hedden T,
    2. Gabrieli JD
    . Insights into the ageing mind: a view from cognitive neuroscience. Nat Rev Neurosci 2004; 5: 87– 96
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Shaywitz BA,
    2. Shaywitz SE,
    3. Pugh KR,
    4. et al
    . Sex-differences in the functional-organization of the brain for language. Nature 1995; 373: 607– 09
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Jaeger JJ,
    2. Lockwood AH,
    3. Van Valin RD,
    4. et al
    . Sex differences in brain regions activated by grammatical and reading tasks. Neuroreport 1998; 9: 2803– 07
    PubMedWeb of Science
  21. 21.↵
    1. Kansaku K,
    2. Yamaura A,
    3. Kitazawa S
    . Sex differences in lateralization revealed in the posterior language areas. Cereb Cortex 2000; 10: 866– 72
    Abstract/FREE Full Text
  22. 22.↵
    1. Cahill L,
    2. Uncapher M,
    3. Kilpatrick L,
    4. et al
    . Sex-related hemispheric lateralization of amygdala function in emotionally influenced memory: an fMRI investigation. Learn Mem 2004; 11: 261– 66
    Abstract/FREE Full Text
  23. 23.↵
    1. Goldstein JM,
    2. Jerram M,
    3. Poldrack R,
    4. et al
    . Sex differences in prefrontal cortical brain activity during fMRI of auditory verbal working memory. Neuropsychology 2005; 19: 509– 19
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Murphy DG,
    2. DeCarli C,
    3. McIntosh AR,
    4. et al
    . Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch Gen Psychiatry 1996; 53: 585– 94
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Lemaitre H,
    2. Crivello F,
    3. Grassiot B,
    4. et al
    . Age- and sex-related effects on the neuroanatomy of healthy elderly. Neuroimage 2005; 26: 900– 11
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Bassett SS,
    2. Yousem DM,
    3. Cristinzio C,
    4. et al
    . Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain 2006; 129 ( pt 5): 1229– 39
    Abstract/FREE Full Text
  27. 27.↵
    1. Honeycutt NA,
    2. Smith PD,
    3. Aylward E,
    4. et al
    . Mesial temporal lobe measurements on magnetic resonance imaging scans. Psychiatry Res 1998; 83: 85– 94
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Ylikoski R,
    2. Ylikoski A,
    3. Erkinjuntti T,
    4. et al
    . Differences in neuropsychological functioning associated with age, education, neurological status, and magnetic resonance imaging findings in neurologically healthy elderly individuals. Appl Neuropsychol 1998; 5: 1– 14
    CrossRefPubMed
  29. 29.↵
    1. Le Carret N,
    2. Lafont S,
    3. Mayo W,
    4. et al
    . The effect of education on cognitive performances and its implication for the constitution of the cognitive reserve. Dev Neuropsychol 2003; 23: 317– 37
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Scarmeas N,
    2. Zarahn E,
    3. Anderson KE,
    4. et al
    . Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects. Neuroimage 2003; 19: 1215– 27
    CrossRefPubMed
  31. 31.↵
    1. Paus T,
    2. Koski L,
    3. Caramanos Z,
    4. et al
    . Regional differences in the effects of task difficulty and motor output on blood flow response in the human anterior cingulate cortex: a review of 107 PET activation studies. Neuroreport 1998; 9: R37– R47
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Stern Y,
    2. Habeck C,
    3. Moeller J,
    4. et al
    . Brain networks associated with cognitive reserve in healthy young and old adults. Cereb Cortex 2005; 15: 394– 402
    Abstract/FREE Full Text
  33. 33.↵
    1. Mitchell RL
    . The BOLD response during Stroop task-like inhibition paradigms: effects of task difficulty and task-relevant modality. Brain Cogn 2005; 59: 23– 37
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 30 (8)
American Journal of Neuroradiology
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D.M. Yousem, M.A. Yassa, C. Cristinzio, I. Kusevic, M. Mohamed, B.S. Caffo, S.S. Bassett
Intelligence and Medial Temporal Lobe Function in Older Adults: A Functional MR Imaging–Based Investigation
American Journal of Neuroradiology Sep 2009, 30 (8) 1477-1481; DOI: 10.3174/ajnr.A1634

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Intelligence and Medial Temporal Lobe Function in Older Adults: A Functional MR Imaging–Based Investigation
D.M. Yousem, M.A. Yassa, C. Cristinzio, I. Kusevic, M. Mohamed, B.S. Caffo, S.S. Bassett
American Journal of Neuroradiology Sep 2009, 30 (8) 1477-1481; DOI: 10.3174/ajnr.A1634
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