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Research ArticleNeurointervention

Cerecyte versus Platinum Coils in the Treatment of Intracranial Aneurysms: Packing Attenuation and Clinical and Angiographic Midterm Results

I. Linfante, M.J. DeLeo, M.J. Gounis, C.S. Brooks and A.K. Wakhloo
American Journal of Neuroradiology September 2009, 30 (8) 1496-1501; DOI: https://doi.org/10.3174/ajnr.A1617
I. Linfante
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M.J. DeLeo III
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M.J. Gounis
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C.S. Brooks
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A.K. Wakhloo
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    Fig 1.

    Sample case. A, A 61-year-old woman developed subarachnoid hemorrhage (Hunt and Hess scale, grade 4) secondary to a ruptured left PICA aneurysm. Four Cerecyte coils (28.5-cm total length; packing attenuation, 50%) were placed in the aneurysm. B, On immediate postprocedural control angiography, the arrow indicates a small area of contrast filling at the base of the aneurysm. C, This area of contrast filling is no longer visualized at 6-month follow-up (arrow), and the PICA remains patent.

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    Fig 2.

    Sample case. A and B, 3D reconstructive rotational angiograms reveal a ruptured PcomA in a 60-year-old woman with subarachnoid hemorrhage (Hunt and Hess scale, grade 3). A bleb is seen at the inferior aspect of the aneurysm (arrow, A), and a shoulder is visualized at the superior portion (arrow, B ). Coil embolization is performed by using a combination of bare platinum and Cerecyte coils (50% Cerecyte; packing attenuation, 21%). C and D, Immediate postcoiling control angiograms demonstrate residual filling of the bleb (arrow, C ) and shoulder (arrow, D). E and F, Six-month follow-up angiograms demonstrate complete aneurysm occlusion with obliteration of both the bleb (arrow, E) and the shoulder (arrow, F).

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    Table 1:

    Patient demographics and aneurysm characteristics

    DemographicsBare Platinum (%)Cerecyte (%)P Value
    No. patients6563
    No. aneurysms7067
    Age25–8526–87.06
    Female44 (68)43 (68)1.0
    Aneurysm size5.7 ± 2.65.7 ± 2.4.99
    Neck size3.2 ± 1.43.7 ± 1.8.17
    Ruptured29 (41)26 (39).86
    6-Month FU47 (67)45 (67)
    12-Month FU30 (43)36 (54)
    Balloon-assisted12 (17)12 (18)1.0
    Stent-assisted11 (16)10 (15)1.0
    • Note:—FU indicates follow-up

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    Table 2:

    Results of coil embolization

    Bare Platinum (%)Cerecyte (%)P Value
    RS 129 (41)33 (49).39
    RS 227 (39)14 (21)
    RS 314 (20)20 (30)
    Recanalizations11 (23)5 (11).17
    Complications2 Intraop ruptures, 1 arterial dissection2 Intraop ruptures
    Abciximab7 (10)10 (15).44
    Packing attenuation40 ± 2343 ± 28.68
    • Note:—Intraop indicates intraoperative; RS, Raymond score.

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American Journal of Neuroradiology: 30 (8)
American Journal of Neuroradiology
Vol. 30, Issue 8
1 Sep 2009
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I. Linfante, M.J. DeLeo, M.J. Gounis, C.S. Brooks, A.K. Wakhloo
Cerecyte versus Platinum Coils in the Treatment of Intracranial Aneurysms: Packing Attenuation and Clinical and Angiographic Midterm Results
American Journal of Neuroradiology Sep 2009, 30 (8) 1496-1501; DOI: 10.3174/ajnr.A1617

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Cerecyte versus Platinum Coils in the Treatment of Intracranial Aneurysms: Packing Attenuation and Clinical and Angiographic Midterm Results
I. Linfante, M.J. DeLeo, M.J. Gounis, C.S. Brooks, A.K. Wakhloo
American Journal of Neuroradiology Sep 2009, 30 (8) 1496-1501; DOI: 10.3174/ajnr.A1617
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