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Research ArticleNeurointervention
Open Access

Experience with Microaneurysm Formation at the Basilar Terminus in the Rabbit Elastase Aneurysm Model

D. Dai, Y.H. Ding, R. Kadirvel, D.A. Lewis and D.F. Kallmes
American Journal of Neuroradiology February 2010, 31 (2) 300-303; DOI: https://doi.org/10.3174/ajnr.A1823
D. Dai
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Y.H. Ding
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R. Kadirvel
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D.A. Lewis
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D.F. Kallmes
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    Fig 1.

    A, DSA of the right vertebral artery shows the basilar artery (short arrow) and bilateral PcomAs (long arrows). The right PcomA is tortuous and dilated and nearly as large as the basilar artery, compared with the left PcomA (thin long arrow). B, Lateral DSA from the same rabbit subject shows marked enlargement of the right PcomA, which fills, in retrograde fashion, the ECA branches.

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    Fig 2.

    A photograph of the basilar artery and its branches shows that both PcomAs are present and that the right PcomA (long arrow) is larger than the left one (short arrow).

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    Fig 3.

    Typical photomicrographs of the BT show that the IEL is intact and continuous at the BT. A, The basilar artery and its bifurcation (HE, original magnification ×40). B and C, The IEL (black line) at the BT is intact and continuous (B, VVG, original magnification ×100) (C, VVG, original magnification ×200). The medial layer, immediately underneath the IEL and stained light brown, is also intact and continuous. No bulge-like localized dilation or nascent aneurysm formation is observed.

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    Fig 4.

    Photomicrographs of the BT from a 30-week subject. A, The basilar artery, BT, and 2 concave structures along the P1 segments labeled as 1 and 2 (arrows) for correlation with higher magnification views in B and C (VVG, original magnification ×40). B, The concave structure 1 from A, with an intact IEL, is the black line along the luminal side of the wall, contiguous with the adjacent vessel wall and with the intact but thinned media (VVG, original magnification ×200). C, Concave structure 2 from A, with an intact IEL (VVG, original magnification ×200). D, The serial (adjacent) section of A shows that the concave structures in A−C are branch vessels (arrows) (HE, original magnification ×40). E, Intact and continued IEL of the BT (VVG, original magnification ×200).

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American Journal of Neuroradiology: 31 (2)
American Journal of Neuroradiology
Vol. 31, Issue 2
1 Feb 2010
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D. Dai, Y.H. Ding, R. Kadirvel, D.A. Lewis, D.F. Kallmes
Experience with Microaneurysm Formation at the Basilar Terminus in the Rabbit Elastase Aneurysm Model
American Journal of Neuroradiology Feb 2010, 31 (2) 300-303; DOI: 10.3174/ajnr.A1823

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Experience with Microaneurysm Formation at the Basilar Terminus in the Rabbit Elastase Aneurysm Model
D. Dai, Y.H. Ding, R. Kadirvel, D.A. Lewis, D.F. Kallmes
American Journal of Neuroradiology Feb 2010, 31 (2) 300-303; DOI: 10.3174/ajnr.A1823
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