Article Figures & Data
Figures
- Fig 1.
A−C, DSA with selective ICA injection pre- (A) and postembolization (B) at the origin of the ICA, resulting in an occlusion of the right MCA (arrow in B). C, DWI performed 4 hours later confirms the presence of a right MCA infarct (arrow). D, C-arm CT and PCT (E) demonstrate corresponding decreased CBV as determined both by the color maps and measured values in the respective regions of interest. CBV values are in milliliters per 100 grams of brain tissue.
- Fig 2.
A and B, DSA with selective ICA injection pre-embolization demonstrates tortuosity of the ICA (asterisk in A). Embolization was performed near the origin of the right MCA, from a vertebral artery approach leading to occlusion of the proximal MCA. MCA infarct (arrow) was validated by DWI (C) done 4 hours after embolization. C-arm CT (D) and PCT (E) reveal corresponding decreased CBV as determined both by the color maps and measured values in the respective regions of interest.
Tables
Mean CBV (mL/100 g) P Valueb PCT infarct vs PCT normal 0.814/1.378 .0039 C-arm 1 infarct vs C-arm 1 normalc 0.662/1.429 .0008 C-arm 1.5 infarct vs C-arm 1.5 normald 0.561/1.163 .0014 PCT infarct vs C-arm 1 infarct 0.814/0.662 .158 PCT infarct vs C-arm 1.5 infarct 0.121/0.178 .072 PCT normal vs C-arm 1 normalc 1.378/1.429 .791 PCT normal vs C-arm 1.5 normal 1.378/1.163 .241 a Mean CBV values in the regions of interest within the infarcted territory (infarct) and in the normal contralateral side (normal) in the 10 canine experiments.
b Paired 2-sample t test.
c 1 indicates 1 mL/s; C-arm 1, values from the first C-arm CT acquisition.
d C-arm 2 indicates values from the second C-arm CT acquisition.
Mean CBV Ratio (infarct/normal) P Valueb PCT normal vs C-arm 1 normalc 0.626/0.496 .199 PCT normal vs C-arm 1.5 normald 0.626/0.467 .166 a Mean ratio of region-of-interest values between the infarcted territory (infarct) and the normal contralateral side (normal) in the 10 canine experiments.
b Paired 2-sample t test.
c 1 indicates 1 mL/s.
d 1.5 indicates 1.5 mL/s.
Reader 1 Reader 2 Reader 3 Mean TP readings of PCT 75.0% 70% 75% 73.3% TP readings of C-arm CT 83.3% 83.3% 86.7% 84.4% FP readings of PCT 0% 5% 0% 1.7% FP readings of C-arm CT 0% 3.3% 6.7% 3.3% FN readings of PCT 25% 25% 25% 25% FN readings of C-arm CT 16.7% 13.3% 6.7% 12.2% a Percentage of TP (infarct was correctly identified), FP (CBV abnormality identified in a location where there was no DWI abnormality), and FN (no abnormality identified in location where there was a DWI abnormality) readings are given for each reader individually and the mean of all 3 readers. C-arm CT readings demonstrate a better correlation with the criterion standard DWI. Most interesting, the rate of FP readings is very low. Please note the discrepancy of FN PCT and FN C-arm CT readings.
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