Article Figures & Data
Figures
- Fig 1.
ROC of BF (A) and PS (B) values for predicting local tumor control.
- Fig 2.
Kaplan-Meier survival analysis of BF (A) and PS (B) values with recurrence (38 subjects) as the end point of local tumor control. The solid and dashed lines are according to values (in mL per minute per 100 mL of tissue) derived from the ROC.
- Fig 3.
BF (A) and BV (B) parametric maps of a 69-year-old man with SCCA of the oropharynx on the left side. Visual analysis (as also confirmed by the region-of-interest measurements) shows 2 functionally different tumor compartments regarding BF and BV properties and, thus, a BF-BV mismatch.
Tables
Mean and median perfusion-associated values in the pooled patient populations and separately in the patient subgroups with (38 subjects) and without recurrence (46 subjects)
Pooled Patients Patients without Recurrence Patients with Recurrence Mean ± SD Median (Range) Mean ± SD Median (Range) Mean ± SD Median (Range) BF (mL/min/100 mL) 82.9 ± 28.7 78 (34–198) 88.2 ± 28.5 87 (56–198)a 76.5 ± 28 69.5 (34–162)a BV (mL/100 mL) 5.5 ± 1.7 5.2 (2.4–10) 5.6 ± 1.8 5.2 (2.4–10)b 5.4 ± 1.7 5 (3–9)b MTT (seconds) 7 ± 2.9 6.5 (3.5–20) 6.7 ± 2.9 6 (3.6–20)c 7.4 ± 2.9 6.9 (3.5–17)c PS (mL/min/100 mL) 16.3 ± 4.9 16 (7.6–35) 17.8 ± 4.6 17 (9.4–31)d 14.5 ± 4.9 14 (7.6–35)d a P = .0241.
b P = .72.
c P = .24.
d P = .0001.
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