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Research ArticleBrain

Assessment of Intracranial Arterial Stenosis with Multidetector Row CT Angiography: A Postprocessing Techniques Comparison

L. Saba, R. Sanfilippo, R. Montisci and G. Mallarini
American Journal of Neuroradiology May 2010, 31 (5) 874-879; DOI: https://doi.org/10.3174/ajnr.A1976
L. Saba
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R. Sanfilippo
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R. Montisci
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G. Mallarini
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    Fig 1.

    Sixty-three-year-old female patient: postprocessed VR (A), MIP (B), corona MPR (C), and CPR images (D, E).

Tables

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    Table 1:

    Location of intracranial arterial stenosed segments detected by observers in consensus

    No. (%) of Lesions (n = 215)No. (%) of Lesions (n = 215)
    High cervical ICA right7 (3.2)54 (25)
    High cervical ICA left7 (3.2)
    Petrous ICA right9 (4.2)
    Petrous ICA left12 (6.7)
    Cavernous ICA right6 (2.8)
    Cavernous ICA left4 (1.9)
    Supraclinoid ICA right4 (1.9)
    Supraclinoid ICA left5 (2.3)
    A1 right2 (0.9)7 (3)
    A1 left1 (0.5)
    A2 right2 (0.9)
    A2 left2 (0.9)
    M1 right9 (4.2)31 (14)
    M1 left7 (3.2)
    M2 right8 (3.7)
    M2 left7 (3.2)
    Intracranial vertebral right23 (10.7)49 (23)
    Intracranial vertebral left26 (12)
    P1 right12 (6.7)47 (22)
    P1 left8 (3.7)
    P2 right11 (5.1)
    P2 left16 (7.4)
    Proximal basilar13 (6)27 (13)
    Distal basilar14 (6.5)
    • View popup
    Table 2:

    Number of intracranial arterial stenosed segments according to observers and postprocessing techniques

    Number of Identified Lesions
    Observer 1Observer 2
    MPRCPRMIPVRMPRCPRMIPVR
    High cervical ICA right35663477
    High cervical ICA left34774577
    Petrous ICA right45583469
    Petrous ICA left5671125811
    Cavernous ICA right28554444
    Cavernous ICA left32434345
    Supraclinoid ICA right33444245
    Supraclinoid ICA left34552354
    A1 right01220123
    A1 left00111021
    A2 right01120112
    A2 left00120022
    M1 right36782356
    M1 left24673247
    M2 right34963388
    M2 left2110621117
    Intracranial vertebral right81516216121721
    Intracranial vertebral left121421249192225
    P1 right2581137912
    P1 left36694877
    P2 right589143489
    P2 left61214138141313
    Proximal basilar791214981010
    Distal basilar6911129101012
    Total8513217720188123176197
    • View popup
    Table 3:

    Kappa value between observers in the identification of intracranial arterial segments according to different postprocessing techniques

    Observer 1Reference
    MIPMPRVRCPR
    Observer 2
        MIP0.861 (0.019)0.225 (0.037)0.53 (0.033)0.39 (0.037)0.59 (0.031)
        MPR0.414 (0.038)0.282 (0.047)0.481 (0.037)0.348 (0.043)0.511 (0.035)
        VR0.627 (0.030)0.36 (0.037)0.878 (0.019)0.543 (0.034)0.951 (0.011)
        CPR0.414 (0.037)0.282 (0.043)0.566 (0.034)0.611 (0.037)0.635 (0.031)
    Reference0.653 (0.029)0.397 (0.036)0.909 (0.015)0.552 (0.033)NC
    • Note:—Numbers in parentheses indicate SD.

    • View popup
    Table 4:

    Observer 1: Sensitivity, specificity, NPV, and PPV of the different reconstruction methods

    SensitivitySpecificityPPVNPV
    MPR0.302 (95% CI = 0.241–0.364)0.989 (95% CI = 0.984–0.994)0.765 (95% CI = 0.675–0.885)0.923 (95% CI = 0.911–0.935)
    CPR0.474 (95% CI = 0.408–0.541)0.984 (95% CI = 0.978–0.989)0.773 (95% CI = 0.701–0.844)0.941 (95% CI = 0.930–0.951)
    MIP0.637 (95% CI = 0.573–0.701)0.974 (95% CI = 0.967–0.982)0.745 (95% CI = 0.682–0.808)0.958 (95% CI = 0.949–0.967)
    VR0.888 (95% CI = 0.846–0.930)0.995 (95% CI = 0.991–0.998)0.950 (95% CI = 0.920–0.980)0.987 (95% CI = 0.982–0.992)
    • View popup
    Table 5:

    Observer 2: Sensitivity, specificity, NPV, and PPV of the different reconstruction methods

    SensitivitySpecificityPPVNPV
    MPR0.381 (95% CI = 0.316–0.446)0.997 (95% CI = 0.994–0.999)0.824 (95% CI = 0.734–0.894)0.932 (95% CI = 0.921–0.943)
    CPR0.521 (95% CI = 0.454–0.588)0.994 (95% CI = 0.990–0.998)0.762 (95% CI = 0.670–0.884)0.946 (95% CI = 0.936–0.956)
    MIP0.572 (95% CI = 0.506–0.638)0.971 (95% CI = 0.963–0.979)0.699 (95% CI = 0.631–0.767)0.951 (95% CI = 0.941–0.960)
    VR0.916 (95% CI = 0.879–0.953)0.999 (95% CI = 0.998–1)0.995 (95% CI = 0.985–1)0.990 (95% CI = 0.986–0.995)
    • View popup
    Table 6:

    Observer 1 quality image evaluation for each patient by comparing various reconstruction methods

    Image QualityTotal Score
    PoorFairGoodExcellent
    MPR7293811138
    CPR1174423174
    MIP6233818153
    VR275026185
    • Note:—Poor = 0, fair = 1, good = 2, and excellent = 3.

    • View popup
    Table 7:

    Observer 2 quality image evaluation for each patient by comparing various reconstruction methods

    Image QualityTotal Score
    PoorFairGoodExcellent
    MPR5333710137
    CPR1154821174
    MIP3244612152
    VR0135220177
    • Note:—Poor = 0, fair = 1, good = 2, and excellent = 3.

    • View popup
    Table 8:

    Kappa value between observers in the quality image evaluation according to different postprocessing techniques

    Observer 1
    MIPMPRVRCPR
    Observer 2
        MIP0.783 (0.085)0.596 (0.073)0.406 (0.078)0.416 (0.82)
        MPR0.544 (0.074)0.676 (0.070)0.407 (0.064)0.239 (0.79)
        VR0.465 (0.076)0.254 (0.074)0.704 (0.070)0.363 (0.083)
        CPR0.418 (0.79)0.245 (0.079)0.409 (0.082)0.728 (0.067)
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American Journal of Neuroradiology: 31 (5)
American Journal of Neuroradiology
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Cite this article
L. Saba, R. Sanfilippo, R. Montisci, G. Mallarini
Assessment of Intracranial Arterial Stenosis with Multidetector Row CT Angiography: A Postprocessing Techniques Comparison
American Journal of Neuroradiology May 2010, 31 (5) 874-879; DOI: 10.3174/ajnr.A1976

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Assessment of Intracranial Arterial Stenosis with Multidetector Row CT Angiography: A Postprocessing Techniques Comparison
L. Saba, R. Sanfilippo, R. Montisci, G. Mallarini
American Journal of Neuroradiology May 2010, 31 (5) 874-879; DOI: 10.3174/ajnr.A1976
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