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MR Imaging in Multiple Sclerosis: Review and Recommendations for Current Practice

K.-O. Lövblad, N. Anzalone, A. Dörfler, M. Essig, B. Hurwitz, L. Kappos, S.-K. Lee and M. Filippi
American Journal of Neuroradiology June 2010, 31 (6) 983-989; DOI: https://doi.org/10.3174/ajnr.A1906
K.-O. Lövblad
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N. Anzalone
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A. Dörfler
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M. Essig
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B. Hurwitz
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L. Kappos
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S.-K. Lee
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M. Filippi
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    Fig 1.

    Predictive value of gadolinium-enhanced MR imaging for relapses in MS: a meta-analysis. Reprinted with permission from Lancet.24

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    Fig 2.

    Typical MS with brain lesions.

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    Fig 3.

    Comparison of rates of Gd3+ release for 1 mmol/L solutions of gadolinium-containing contrast agents in native human serum from healthy volunteers at 37°C. Reprinted with permission from Frenzel T, Lengsfeld P, Shirmer H, et al. Stability of gadolinium-based magnetic resonance imaging contrast agents in human serum at 37°C. Invest Radiol 2008;43:817–28.

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    Fig 4.

    Case study shows brain lesion enhancement with gadobutrol. Images were obtained at 3, 6, 9, and 12 minutes postinjection.

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American Journal of Neuroradiology: 31 (6)
American Journal of Neuroradiology
Vol. 31, Issue 6
1 Jun 2010
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Cite this article
K.-O. Lövblad, N. Anzalone, A. Dörfler, M. Essig, B. Hurwitz, L. Kappos, S.-K. Lee, M. Filippi
MR Imaging in Multiple Sclerosis: Review and Recommendations for Current Practice
American Journal of Neuroradiology Jun 2010, 31 (6) 983-989; DOI: 10.3174/ajnr.A1906

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MR Imaging in Multiple Sclerosis: Review and Recommendations for Current Practice
K.-O. Lövblad, N. Anzalone, A. Dörfler, M. Essig, B. Hurwitz, L. Kappos, S.-K. Lee, M. Filippi
American Journal of Neuroradiology Jun 2010, 31 (6) 983-989; DOI: 10.3174/ajnr.A1906
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  • Article
    • Abstract
    • Abbreviations
    • Applications of MR Imaging in MS
    • Techniques and Protocols for MR Imaging in MS
    • Summary of Expert Meeting Recommendations
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Cited By...

  • Current and Emerging Therapies in Multiple Sclerosis: Implications for the Radiologist, Part 1--Mechanisms, Efficacy, and Safety
  • Multiple Sclerosis: An Update
  • MS Lesions Are Better Detected with 3D T1 Gradient-Echo Than with 2D T1 Spin-Echo Gadolinium-Enhanced Imaging at 3T
  • Accuracy of Postcontrast 3D Turbo Spin-Echo MR Sequence for the Detection of Enhanced Inflammatory Lesions in Patients with Multiple Sclerosis
  • Practice patterns of US neurologists in patients with SPMS and PPMS: A consensus study
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    American Journal of Roentgenology 2013 200 1
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    Aviv Mezer, Jason D Yeatman, Nikola Stikov, Kendrick N Kay, Nam-Joon Cho, Robert F Dougherty, Michael L Perry, Josef Parvizi, Le H Hua, Kim Butts-Pauly, Brian A Wandell
    Nature Medicine 2013 19 12
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    Annals of Neurology 2011 70 1
  • MRI in the assessment and monitoring of multiple sclerosis: an update on best practice
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    Therapeutic Advances in Neurological Disorders 2017 10 6
  • A contrast-adaptive method for simultaneous whole-brain and lesion segmentation in multiple sclerosis
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    NeuroImage 2021 225
  • Multiscale Amplitude-Modulation Frequency-Modulation (AM–FM) Texture Analysis of Multiple Sclerosis in Brain MRI Images
    C.P. Loizou, V. Murray, M.S. Pattichis, I. Seimenis, M. Pantziaris, C.S. Pattichis
    IEEE Transactions on Information Technology in Biomedicine 2011 15 1
  • Evaluation of MS related central fatigue using MR neuroimaging methods: Scoping review
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    Journal of the Neurological Sciences 2019 400
  • Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome
    C.P. Loizou, S. Petroudi, I. Seimenis, M. Pantziaris, C.S. Pattichis
    Journal of Neuroradiology 2015 42 2

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