Article Figures & Data
Figures
- Fig 1.
Axial T2-weighted image demonstrates hyperintense lesions encompassing both dentate nuclei and surrounding white matter; this image also shows region-of-interest placement for MRS.
- Fig 2.
Spectrum obtained from case 1 (1.5T; STEAM; TR/TE, 1500/30 ms) demonstrates lipid peaks at 0.9 and 1.3 ppm. Notice also a slight decrease in the NAA peak.
- Fig 3.
Spectrum obtained from case 2 (3T; PRESS; TR/TE, 1871/35 ms) demonstrates lipid peaks at 0.9 and 1.3 ppm. Notice also a marked decrease in the NAA peak and an increase in the mIns peak.
- Fig 4.
Spectrum obtained from case 3 (3T; PRESS; TR/TE, 1871/35 ms) demonstrates lipid peaks at 0.9 and 1.3 ppm. Notice also a slight trend toward a decrease in the NAA peak.
Tables
Short TE (30–35 ms) single-voxel MRS data: cerebellar tissue and absolute concentrationsa
B0 (T) Lip09 (a.u.) Lip13 (a.u.) NAA (a.u.) Cr (a.u.) Cho (a.u.) mIns (a.u.) Controls (n = 10) 1.5 4.93 ± 1.60 7.46 ± 4.23 6.12 ± 1.69 5.87 ± 1.50 1.76 ± 0.35 5.18 ± 1.55 Case 1 1.5 12.90 22.69 2.24 4.43 1.87 5.73 Case 2 1.5 14.52 19.53 2.00 5.44 2.23 7.32 Case 2 3.0 14.33 12.99 1.83 5.95 2.16 8.47 Case 3 3.0 12.62 13.43 4.80 6.68 2.36 5.09 a Metabolite values from controls are expressed as mean ± SD. Absolute metabolite concentrations are expressed as i.u., scaled to internal water signal. Control values were obtained at 1.5T from a healthy group of 10 subjects (mean age, 17 ± 4 years).
