Reconciling Neuroimaging and Clinical Findings in Aicardi-Goutières Syndrome: An Autoimmune-Mediated Encephalopathy

Upper row: CT scan and T2 turbo spin-echo image of the cerebellum. On the CT scan, diffuse calcifications in both cerebellar hemispheres are depicted. These calcifications are not visible on the T2 turbo spin-echo image. Lower row: CT scan and T2* weighted image of the cerebrum. Both images are at the level of the centrum semiovale. On the CT scan, punctuate calcinations are visible in the left frontal lobe (arrowhead). On the T2* image, leukoencephalopathic changes of the white matter are depicted. A small vacuole is visible on the left side at the site of the calcification (arrow), along with susceptibility artifacts.