Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Review ArticleReview Article
Open Access

Fluid-Attenuated Inversion Recovery Vascular Hyperintensities: An Important Imaging Marker for Cerebrovascular Disease

A. Azizyan, N. Sanossian, M.A. Mogensen and D.S. Liebeskind
American Journal of Neuroradiology November 2011, 32 (10) 1771-1775; DOI: https://doi.org/10.3174/ajnr.A2265
A. Azizyan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N. Sanossian
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.A. Mogensen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D.S. Liebeskind
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Schellinger PD,
    2. Fiebach JB,
    3. Hacke W
    . Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status. Stroke 2003;34:575–83
    Abstract/FREE Full Text
  2. 2.↵
    1. Warach S
    . Measurement of the ischemic penumbra with MRI: it's about time. Stroke 2003;34:2533–34
    FREE Full Text
  3. 3.↵
    1. Cosnard G,
    2. Duprez T,
    3. Grandin C,
    4. et al
    . Fast FLAIR sequence for detecting major vascular abnormalities during the hyperacute phase of stroke: a comparison with MR angiography. Neuroradiology 1999;41:342–46
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Kamran S,
    2. Bates V,
    3. Bakshi R,
    4. et al
    . Significance of hyperintense vessels on FLAIR MRI in acute stroke. Neurology 2000;55:265–69
    Abstract/FREE Full Text
  5. 5.↵
    1. Maeda M,
    2. Yamamoto T,
    3. Daimon S,
    4. et al
    . Arterial hyperintensity on fast fluid-attenuated inversion recovery images: a subtle finding for hyperacute stroke undetected by diffusion-weighted MR imaging. AJNR Am J Neuroradiol 2001;22:632–36
    Abstract/FREE Full Text
  6. 6.↵
    1. Toyoda K,
    2. Ida M,
    3. Fukuda K
    . Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia. AJNR Am J Neuroradiol 2001;22:1021–29
    Abstract/FREE Full Text
  7. 7.↵
    1. Tsushima Y,
    2. Endo K
    . Significance of hyperintense vessels on FLAIR MRI in acute stroke. Neurology 2001;56:1248–49
    FREE Full Text
  8. 8.↵
    1. Iancu-Gontard D,
    2. Oppenheim C,
    3. Touze E,
    4. et al
    . Evaluation of hyperintense vessels on FLAIR MRI for the diagnosis of multiple intracerebral arterial stenoses. Stroke 2003;34:1886–91
    Abstract/FREE Full Text
  9. 9.↵
    1. Sanossian N,
    2. Saver JL,
    3. Alger JR,
    4. et al
    . Angiography reveals that fluid-attenuated inversion recovery vascular hyperintensities are due to slow flow, not thrombus. AJNR Am J Neuroradiol 2009;30:564–68
    Abstract/FREE Full Text
  10. 10.↵
    1. Lee KY,
    2. Latour LL,
    3. Luby M,
    4. et al
    . Distal hyperintense vessels on FLAIR: an MRI marker for collateral circulation in acute stroke? Neurology 2009;72:1134–39
    Abstract/FREE Full Text
  11. 11.↵
    1. Sanossian N,
    2. Ances BM,
    3. Shah SH,
    4. et al
    . FLAIR vascular hyperintensity may predict stroke after TIA. Clin Neurol Neurosurg 2007;109:617–19
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Schellinger PD,
    2. Chalela JA,
    3. Kang D-W,
    4. et al
    . Diagnostic and prognostic value of early MR imaging vessel signs in hyperacute stroke patients imaged <3 hours and treated with recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2005;26:618–24
    Abstract/FREE Full Text
  13. 13.↵
    1. Goldstein LB,
    2. Adams R,
    3. Becker K,
    4. et al
    . Primary prevention of ischemic stroke: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke 2001;32:280–99
    FREE Full Text
  14. 14.↵
    1. Jo KD,
    2. Saver JL,
    3. Starkman S,
    4. et al
    . Predictors of recanalization with mechanical thrombectomy for acute ischemic stroke (abstract). Stroke 2008;39:599
  15. 15.↵
    1. Liebeskind DS
    . Collateral therapeutics for cerebral ischemia. Expert Rev Neurother 2004;4:255–65
    CrossRefPubMed
  16. 16.↵
    1. Liebeskind DS
    . Collaterals in acute ischemic stroke: beyond the clot. Neuroimaging Clin N Am 2005;15:553–73
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Liebeskind DS,
    2. Hao Q,
    3. Sanossian N,
    4. et al
    . Leptomeningeal collateral perfusion in acute MCA occlusion reveals inherent vulnerability to failure: quantifying the hemodynamics of FLAIR vascular hyperintensity. Stroke 2010;41:e21–22
  18. 18.↵
    1. Kawashima M,
    2. Noguchi T,
    3. Takase Y,
    4. et al
    . Unilateral hemispheric proliferation of ivy sign on fluid-attenuated inversion recovery images in Moyamoya disease correlates highly with ipsilateral hemispheric decrease of cerebrovascular reserve. AJNR Am J Neuroradiol 2009;30:1709–16 Epub 2009 Aug 27
    Abstract/FREE Full Text
  19. 19.↵
    1. Johnston SC,
    2. Gress DR,
    3. Browner WS,
    4. et al
    . Short-term prognosis after emergency department diagnosis of TIA. JAMA 2000;284:2901–06
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Sanossian N,
    2. Ovbiagele B
    . The risk of stroke within a week of minor stroke or transient ischemic attack. Expert Opin Pharmacother 2008;9:2069–76
    CrossRefPubMed
  21. 21.↵
    1. Flacke S,
    2. Urbach H,
    3. Keller E,
    4. et al
    . Middle cerebral artery (MCA) susceptibility sign at susceptibility-based perfusion MR imaging: clinical importance and comparison with hyperdense MCA sign at CT. Radiology 2000;215:476–82
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 32 (10)
American Journal of Neuroradiology
Vol. 32, Issue 10
1 Nov 2011
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Fluid-Attenuated Inversion Recovery Vascular Hyperintensities: An Important Imaging Marker for Cerebrovascular Disease
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
A. Azizyan, N. Sanossian, M.A. Mogensen, D.S. Liebeskind
Fluid-Attenuated Inversion Recovery Vascular Hyperintensities: An Important Imaging Marker for Cerebrovascular Disease
American Journal of Neuroradiology Nov 2011, 32 (10) 1771-1775; DOI: 10.3174/ajnr.A2265

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Fluid-Attenuated Inversion Recovery Vascular Hyperintensities: An Important Imaging Marker for Cerebrovascular Disease
A. Azizyan, N. Sanossian, M.A. Mogensen, D.S. Liebeskind
American Journal of Neuroradiology Nov 2011, 32 (10) 1771-1775; DOI: 10.3174/ajnr.A2265
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Identification of FVH
    • Pathophysiology Resulting in FVH
    • Epidemiology of FVH
    • Clinical Utility
    • Conclusions and Future Directions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Hyperintense vessel sign in vertebrobasilar dolichoectasia
  • Association of fluid-attenuated inversion recovery vascular hyperintensity with ischaemic events in internal carotid artery or middle cerebral artery occlusion
  • FLAIR Vascular Hyperintensities as a Surrogate of Collaterals in Acute Stroke: DWI Matters
  • Ivy Sign in Moyamoya Disease: A Comparative Study of the FLAIR Vascular Hyperintensity Sign Against Contrast-Enhanced MRI
  • Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis
  • FLAIR vascular hyperintensities predict early ischemic recurrence in TIA
  • Do Fluid-Attenuated Inversion Recovery Vascular Hyperintensities Represent Good Collaterals before Reperfusion Therapy?
  • Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion
  • Clinical Significance of Fluid-Attenuated Inversion Recovery Vascular Hyperintensities in Borderzone Infarcts
  • Fluid-Attenuated Inversion Recovery Vascular Hyperintensities-Diffusion-Weighted Imaging Mismatch Identifies Acute Stroke Patients Most Likely to Benefit From Recanalization
  • Susceptibility Vessel Sign on MRI Predicts Favorable Clinical Outcome in Patients with Anterior Circulation Acute Stroke Treated with Mechanical Thrombectomy
  • Hyperintense Vessels on FLAIR: Hemodynamic Correlates and Response to Thrombolysis
  • Do FLAIR Vascular Hyperintensities beyond the DWI Lesion Represent the Ischemic Penumbra?
  • FLAIR vascular hyperintensity resolution in a TIA patient: Clinical-radiologic correlation
  • Hyperintense Basilar Artery on FLAIR MR Imaging: Diagnostic Accuracy and Clinical Impact in Patients with Acute Brain Stem Stroke
  • Hyperintense Vessels on Acute Stroke Fluid-Attenuated Inversion Recovery Imaging: Associations With Clinical and Other MRI Findings
  • Crossref (82)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Identification of high-risk carotid plaque with MRI-based radiomics and machine learning
    Ranying Zhang, Qingwei Zhang, Aihua Ji, Peng Lv, Jingjing Zhang, Caixia Fu, Jiang Lin
    European Radiology 2021 31 5
  • Do FLAIR Vascular Hyperintensities beyond the DWI Lesion Represent the Ischemic Penumbra?
    L. Legrand, M. Tisserand, G. Turc, O. Naggara, M. Edjlali, C. Mellerio, J.-L. Mas, J.-F. Méder, J.-C. Baron, C. Oppenheim
    American Journal of Neuroradiology 2015 36 2
  • Hyperintense Vessels on Acute Stroke Fluid-Attenuated Inversion Recovery Imaging
    Bastian Cheng, Martin Ebinger, Anna Kufner, Martin Köhrmann, Ona Wu, Dong-Wha Kang, David Liebeskind, Thomas Tourdias, Oliver C. Singer, Soren Christensen, Steve Warach, Marie Luby, Jochen B. Fiebach, Jens Fiehler, Christian Gerloff, Götz Thomalla
    Stroke 2012 43 11
  • Susceptibility Vessel Sign on MRI Predicts Favorable Clinical Outcome in Patients with Anterior Circulation Acute Stroke Treated with Mechanical Thrombectomy
    R. Bourcier, S. Volpi, B. Guyomarch, B. Daumas-Duport, A. Lintia-Gaultier, C. Papagiannaki, J.M. Serfaty, H. Desal
    American Journal of Neuroradiology 2015 36 12
  • Collateral lessons from recent acute ischemic stroke trials
    David S. Liebeskind
    Neurological Research 2014 36 5
  • Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion
    Dezhi Liu, Fabien Scalzo, Neal M. Rao, Jason D. Hinman, Doojin Kim, Latisha K. Ali, Jeffrey L. Saver, Wen Sun, Qiliang Dai, Xinfeng Liu, David S. Liebeskind
    Stroke 2016 47 11
  • Hyperintense Vessels on FLAIR: Hemodynamic Correlates and Response to Thrombolysis
    A. Kufner, I. Galinovic, V. Ambrosi, C.H. Nolte, M. Endres, J.B. Fiebach, M. Ebinger
    American Journal of Neuroradiology 2015 36 8
  • Imaging Evaluation of Collaterals in the Brain: Physiology and Clinical Translation
    Sunil A. Sheth, David S. Liebeskind
    Current Radiology Reports 2014 2 1
  • Do Fluid-Attenuated Inversion Recovery Vascular Hyperintensities Represent Good Collaterals before Reperfusion Therapy?
    E. Mahdjoub, G. Turc, L. Legrand, J. Benzakoun, M. Edjlali, P. Seners, S. Charron, W. Ben Hassen, O. Naggara, J.-F. Meder, J.-L. Mas, J.-C. Baron, C. Oppenheim
    American Journal of Neuroradiology 2018 39 1
  • Fluid-Attenuated Inversion Recovery Vascular Hyperintensities–Diffusion-Weighted Imaging Mismatch Identifies Acute Stroke Patients Most Likely to Benefit From Recanalization
    Laurence Legrand, Marie Tisserand, Guillaume Turc, Myriam Edjlali, David Calvet, Denis Trystram, Pauline Roca, Olivier Naggara, Jean-Louis Mas, Jean-Francois Méder, Jean-Claude Baron, Catherine Oppenheim
    Stroke 2016 47 2

More in this TOC Section

  • Giant Cell Arteritis: Important Imaging Findings
  • DCE MRI in Spinal Disease Assessment
  • Cerebrovascular Anomalies in Fetal Imaging
Show more Review Article

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire