Article Figures & Data
Figures
- Fig 1.
Effects of brain irradiation on the place navigation function of rats in a water maze. Rats exposed to different doses of fractionated irradiation treatments were subjected to the Morris water maze test. The latency of target finding (A) and swimming distance (B) was plotted and shown as indicated. One asterisk indicates P < .05; double asterisks, P < .01, compared with their corresponding sham.
- Fig 2.
Effects of brain irradiation on the space probe function of rats in a water maze. Rats exposed to different doses of fractionated irradiation treatments were subjected to the Morris water maze test. The journey distance of target to total (A) and target quadrant (B) staying time was plotted and shown as indicated. The asterisk indicates P < .05 compared with the corresponding sham.
- Fig 3.
Effects of brain irradiation on BWC and BBB permeability. A, Water content of the brain is determined by the method of dry and wet weight. Water content in brain: (wet weight − dry weight) / wet weight × 100%. B, BBB permeability is expressed as micrograms of EB per milligram of brain tissue (microgram/gram). The asterisk indicates P < .05; double asterisks, P < .01; number sign, P < .001, compared with their corresponding sham.
- Fig 4.
Increased GFAP+ astrocytes in the hippocampus after irradiation. A, Quantification of GFAP+ astrocytes in hippocampus. B−D, Representative IF results with anti-GFAP staining (green) in the hippocampus of the control group (B), the 20-Gy group (C), and the 40-Gy irradiated group (D) 4 weeks' postirradiation. Note a significant increase in GFAP+ fibers in the area of the hippocampus 4 weeks' postirradiation in the 40-Gy group. Scale bar is 100 μmol/L. Double asterisks indicate P < .01.
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