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Research ArticleNeurointervention

Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms

E.G. Klompenhouwer, J.T.A. Dings, R.J. van Oostenbrugge, S. Oei, J.T. Wilmink and W.H. van Zwam
American Journal of Neuroradiology March 2011, 32 (3) 570-575; DOI: https://doi.org/10.3174/ajnr.A2326
E.G. Klompenhouwer
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J.T.A. Dings
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R.J. van Oostenbrugge
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S. Oei
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J.T. Wilmink
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W.H. van Zwam
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    Fig 1.

    Flow diagram of patient selection.

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    Table 1:

    Patient and aneurysm characteristics

    Surgical Group (No.) (%)Endovascular Group (No.) (%)
    No. of patients173 (42.9)230 (57.1)
    Male/female52 (30.1)/121 (69.9)68 (29.6)/162 (70.4)
    Age (yr) (mean)17–77 (53.1)16–97 (53.6)
    No. of aneurysms treated199244
    No. of aneurysms treated per patient
        1153 (88.4)218 (94.8)
        216 (9.2)10 (4.3)
        33 (1.7)2 (0.9)
        51 (0.6)–
    Size of treated aneurysm
        Small (<5 mm)96 (48.2)98 (40.2)
        Medium (5–15 mm)90 (45.2)136 (55.7)
        Large (15–25 mm)13 (6.5)10 (4.1)
    Aneurysm morphology
        Saccular198 (99.5)242 (99.2)
        Dissecting–1 (0.4)
        Fusiform1 (0.5)1 (0.4)
    • View popup
    Table 2:

    Aneurysm location

    LocationSurgical Group (No.) (%)Endovascular Group (No.) (%)
    ICA27 (13.6)69 (28.3)
        Cavernous–2
        Ophthalmic–4
        PcomA2054
        Anterior choroidal artery3–
        Bifurcation49
    ACA79 (39.7)110 (45.1)
        A151
        AcomA66102
        A287
    MCA89 (46.1)24 (9.8)
        Proximal (M1)193
        Bifurcation6219
        M252
    Posterior circulation7 (3.6)41 (16.8)
        Vertebral artery-1
        Basilar artery junction-27
        SCA-3
        PCA12
        PICA68
    Total199 (100)244 (100)
    • View popup
    Table 3:

    Clinical grading at presentation

    HHSurgical Group (No.) (%)Endovascular Group (No.) (%)
    164 (37.0)65 (28.2)
    256 (32.4)65 (28.2)
    317 (9.8)42 (18.3)
    423 (13.3)29 (12.6)
    513 (7.5)29 (12.6)
    Total173230
    • View popup
    Table 4:

    Clinical outcome

    Surgical Group (No.) (%)Endovascular Group (No.) (%)
    mRS
        039 (25.7)53 (28.3)
        134 (22.4)52 (27.8)
        249 (32.2)58 (31.0)
        317 (11.2)10 (5.3)
        49 (5.9)7 (3.7)
        54 (2.6)7 (3.7)
    Total152187
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    Table 5:

    Postprocedural imaging

    Surgical Group (n = 199) (No.) (%)Endovascular Group (n = 244) (No.) (%)
    No. of aneurysms with imaging126 (63.3)244 (100)
    Complete occlusion101 (80.2)149 (61.1)
    Residual neck17 (13.5)60 (24.6)
    Residual aneurysms8 (6.3)35 (14.3)
    No. of aneurysms without imaging73 (36.7)0 (0)
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    Table 6:

    Follow-up after endovascular treatment by postprocedural imaging

    No Changes (No.) (%)Improvement (No.) (%)Increased Recanalization (No). (%)
    Results of postprocedural imaging
        Complete occlusion (n = 114)72 (63.2)–42 (36.8)
        Residual neck (n = 50)24 (48.0)9 (18.0)17 (34.0)
        Residual aneurysm (n = 25)12 (48.0)–13 (52.0)
    Total 189108 (57.1)9 (4.8)72 (38.1)
    • View popup
    Table 7:

    Data on patients with rebleeding after procedure

    Age/SexLocationSize (mm)Initial InterventionPostprocedural Imaging ResultsTime to Rebleed (days)InterventionmRS
    48/FMCA bifurcation8CoilingResidual aneurysm1None6
    56/FAcomA7CoilingResidual neck2None6
    63/MAcomA2CoilingResidual aneurysm1562None6
    49/FMCA M22vResidual neck43None6
    48/FAcomA4CoilingResidual aneurysm83Recoiling4
    70/FAcomA10CoilingResidual aneurysm3373Recoiling6
    44/FAcomA3CoagulationAneurysm regrowth1396Reclipping2
    40/FPcomA5Clipping?a1None6
    65/MAcomA5ClippingClip slippedb57Coiling2
    40/FAcomA15Clipping?a2None6
    47/MMCA bifurcation6ClippingResidual aneurysm507Coiling3
    49/FAcomA4ClippingClip slippedb12Reclipping0
    • a Indicates no postprocedural imaging was performed.

    • b Clip that slipped from the aneurysm became clear at angiography after rebleed.

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American Journal of Neuroradiology: 32 (3)
American Journal of Neuroradiology
Vol. 32, Issue 3
1 Mar 2011
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E.G. Klompenhouwer, J.T.A. Dings, R.J. van Oostenbrugge, S. Oei, J.T. Wilmink, W.H. van Zwam
Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms
American Journal of Neuroradiology Mar 2011, 32 (3) 570-575; DOI: 10.3174/ajnr.A2326

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Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms
E.G. Klompenhouwer, J.T.A. Dings, R.J. van Oostenbrugge, S. Oei, J.T. Wilmink, W.H. van Zwam
American Journal of Neuroradiology Mar 2011, 32 (3) 570-575; DOI: 10.3174/ajnr.A2326
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Cited By...

  • Clinical outcome after surgical clipping or endovascular coiling for cerebral aneurysms: a pragmatic meta-analysis of randomized and non-randomized trials with short- and long-term follow-up
  • Risk Factors for Early Hemorrhagic Complications after Endovascular Coiling of Ruptured Intracranial Aneurysms
  • Comparative Effectiveness of Ruptured Cerebral Aneurysm Therapies: Propensity Score Analysis of Clipping versus Coiling
  • Age-Related Trends in the Treatment and Outcomes of Ruptured Cerebral Aneurysms: A Study of the Nationwide Inpatient Sample 2001-2009
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