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American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

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Research ArticleResearch Perspectives

Hot Topics in Pediatric Neuroradiology

T.Y. Poussaint
American Journal of Neuroradiology June 2011, 32 (6) 993-997; DOI: https://doi.org/10.3174/ajnr.A2663
T.Y. Poussaint
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    Fig 1.

    A, Child undergoing magnetoencephalography. B and C, Split-second delay in children with ASD, in the 100-ms response of the auditory cortex.

  • Fig 2.
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    Fig 2.

    A, Logo for the Alliance for Radiation Safety in Pediatric Imaging (the Image Gently campaign). B, Logo for the Quality Improvement Registry for CT Scans in Children.

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    Fig 3.

    A, Dissociation of canonical components. Upper row shows a typical canonical temporal (auditory) independent component, characterized by bilateral “activation.” Middle and lower rows show 2 separate dissociated components of activation seen in a patient with intractable epilepsy. B, Abnormal right parietal component in a patient with an epileptic focus demonstrated in the same area.

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    Fig 4.

    Brain miswiring in tuberous sclerosis and autism. A and B, These diffusion tensor tractography images of the brain, analyzed and visualized with the CRKit software developed in the Computational Radiology Laboratory at Children's Hospital Boston, Massachusetts, illustrate the disorganization of white matter fibers in a 17-year-old girl with TSC and autism (A) compared with a healthy girl of the same age (B). In the affected girl, the white matter fiber bundles that carry information from the thalamus of the brain to the visual cortex are less organized, with far fewer axons connecting to the cortex. The brighter colors in the healthy brain illustrate greater structural integrity of the tracts.

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    Fig 5.

    Brain miswiring, tuberous sclerosis, and developmental delay. A and B, These diffusion tensor tractography images of the brain illustrate the disorganization of white matter in a 5-year-old girl with TSC and developmental delay (A) compared with a healthy girl of the same age (B). In the affected girl, the white matter fiber bundles that carry information from the thalamus of the brain to the visual cortex are strikingly asymmetric, with far fewer axonal connections on the right side of the brain (which appears at left in these images).

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American Journal of Neuroradiology: 32 (6)
American Journal of Neuroradiology
Vol. 32, Issue 6
1 Jun 2011
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T.Y. Poussaint
Hot Topics in Pediatric Neuroradiology
American Journal of Neuroradiology Jun 2011, 32 (6) 993-997; DOI: 10.3174/ajnr.A2663

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Hot Topics in Pediatric Neuroradiology
T.Y. Poussaint
American Journal of Neuroradiology Jun 2011, 32 (6) 993-997; DOI: 10.3174/ajnr.A2663
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    • Abstract
    • Abbreviations
    • Neuroimaging Advances in Understanding Autism
    • Alliance for Radiation Safety in Pediatric Imaging (Image Gently Program): Size-Corrected Dose (A New Patient Dose Estimate) and First Pediatric National Registry for CT Scans
    • Rest-State fMRI in Pediatric Patients with Intractable Epilepsy
    • Changing the “Rules of Engagement” in Pediatric Mild Traumatic Brain Injury
    • Diffusion Imaging Provides Insight into White Matter Microstructural Integrity in Tuberous Sclerosis Complex
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