Article Figures & Data
Figures
- Fig 1.
TBSS analysis of the white matter skeleton. Voxels demonstrating significantly (P < .01) decreased FA values for the subjects with mTBI compared with the control group are shown in red-yellow. Voxels are thickened into local tracts and overlaid on the white matter skeleton (green). Further cluster details are given in Table 2.
- Fig 2.
TBSS analysis of the white matter skeleton. Voxels demonstrating FA values correlated significantly (P < .01) to MMSE are shown in red-yellow. Voxels are thickened into local tracts and overlaid on the white matter skeleton (green). Further cluster details are given in Table 3.
- Fig 3.
TBSS analysis of the white matter skeleton. Voxels demonstrating FA values correlated significantly (P < .01) to FIQ are shown in red-yellow. Voxels are thickened into local tracts and overlaid on the white matter skeleton (green). Further cluster details are given in Table 4.
Tables
Patients (n = 51) Controls (n = 50) Age (yr) 37.1 ± 10.2 35.8 ± 13.4 Male sex (%) 55.0 60.0 Initial GCS (range) 14.8 ± 0.6 (13–15) Time postinjury (mo) 35.1 ± 26.3 MMSE 27.9 ± 2.4 FIQ (WAIS-R) 87.4 ± 18.5 -
↵a Expressed as mean ± SD.
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- Table 2:
Anatomic location of decreased FA clusters in the mTBI group compared with controls
Hemisphere Anatomic Location MNI Coordinates Z Score No. of Voxels X Y Z Right Superior longitudinal fasciculus 33 −4 22 4.1 8 Left Superior frontal gyrus −16 40 27 3.86 24 Right Insula 41 −1 6 3.74 9 Left Fornix −4 −22 17 3.38 11 - Table 3:
Anatomic locations showing a positive correlation of MMSE and FA values in patients with mTBI
Label Hemisphere Anatomic location MNI Coordinates Z Score No. of Voxels X Y Z A Right Supramarginal gyrus 54 −36 17 4.9 23 B Left Inferior longitudinal fasciculus −26 12 −9 4.22 22 C Right Superior parietal lobule 13 −64 40 3.97 9 D Right Sagittal stratum 31 −41 −5 3.89 13 E Left Middle frontal gyrus −29 1 51 3.88 14 F Right Superior frontal gyrus 21 41 19 3.41 10 G Left Cerebellum −3 −70 −21 3.4 8 H Right Cingulum 27 −37 −8 3.35 8 I Right Cingulum 8 −17 35 3.24 8 J Right Superior occipital gyrus 16 −82 24 3.17 9 - Table 4:
Anatomic locations showing a positive correlation of FIQ and FA values in patients with mTBI
Label Hemisphere Anatomic location MNI Coordinates Z Score No. of Voxels X Y Z A Left Insula −39 −3 3 6.01 19 B Right Cerebellum 29 −69 −33 4.93 8 C Left Cerebellum −6 −55 −45 4.9 9 D Right Sagittal stratum 30 −61 −10 4.79 8 E Right Superior temporal gyrus 57 −34 11 4.59 12 F Left Amygdala −24 2 −22 4.47 12 G Left Precuneus −5 −29 44 4.34 9 H Right Cerebellum 6 −68 −35 4.22 8 I Right Cingulum 4 −49 31 4.2 8 J Right Superior longitudinal fasciculus 37 −39 22 4.1 9 K Right Angular gyrus 46 −45 23 3.95 8 L Right Superior occipital gyrus 24 −76 −15 3.93 13 M Left Cuneus −4 −69 15 3.53 10 N Right Cerebellum 37 −62 −33 3.43 9 O Right Inferior temporal gyrus 42 11 −24 3.41 8 P Left Lenticular fasciculus −14 3 −7 3.39 9 Q Left Fusiform gyrus −34 −29 −18 3.36 8
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