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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleInterventionalE

Cerebral Perfusion Long Term after Therapeutic Occlusion of the Internal Carotid Artery in Patients Who Tolerated Angiographic Balloon Test Occlusion

S. Gevers, D. Heijtel, S.P. Ferns, P. van Ooij, W.J. van Rooij, M.J. van Osch, R. van den Berg, A.J. Nederveen and C.B. Majoie
American Journal of Neuroradiology February 2012, 33 (2) 329-335; DOI: https://doi.org/10.3174/ajnr.A2776
S. Gevers
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D. Heijtel
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S.P. Ferns
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P. van Ooij
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W.J. van Rooij
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M.J. van Osch
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R. van den Berg
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A.J. Nederveen
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C.B. Majoie
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  • Fig 1.
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    Fig 1.

    CBF in hemispheres and flow territories ipsilateral and contralateral to the occlusion side (A) and mean arterial arrival time and trailing edge time ipsilateral and contralateral to the occlusion side (B). Error bars represent corresponding SDs. Significant differences are indicated by an asterisk.

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    Fig 2.

    Axial brain maps showing arterial arrival and trailing edge time in a patient with right ICA occlusion. Delayed arterial arrival and increased trailing edge time can be observed in the right hemisphere.

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    Fig 3.

    MR imaging data of 2 patients with right ICA occlusion, illustrating 2 different patterns of collateral flow. A, MRA data show hypoplasia of both PcomAs. Flow maps obtained by selective ASL illustrate the compensatory flow from the remaining ICA via the AcomA. The flow territory of the remaining ICA (selective tagging of the ICA) is green, and the flow territory of the BA (selective tagging of the BA) is red. B, MRA data show a complete COW, resulting in mixed collateral flow via the AcomA and PcomA as illustrated by velocity data and flow maps.

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    Fig 4.

    Different collateral flow patterns through the circle of Willis and corresponding distribution of flow via the ACA, MCA, and PCA on the occlusion side. Flow has been displayed as a percentage of total flow in the cerebral arteries.

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    Fig 5.

    Timing parameters in the hemisphere on the occlusion side, depicted for each collateral flow type.

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  • Patient characteristics, clinical, and angiographic results

    No.SexAge (yr)Clinical OnsetSideLocationICA OcclusionFUCOW (MRA)SymptomsIschemic Lesions (T2WI FLAIR)
    1F65R CN III, V1, VI palsyRC4Balloons14Hypoplastic PcomAsImprovedBoth hemispheres, unchanged
    2F32R CN III palsyRC4Balloons49CompleteCured–
    3F48Headache nausea, SAHRC4Balloons74CompleteCuredBoth hemispheres, unchanged
    4F48R decreased visual acuityRC4Balloons23Absent contralateral PcomACured–
    5F64R ophthalmoplegiaRC4Coils + balloon35Absent contralateral PcomACured–
    6F60R CN III palsyRC4Coils + balloon20Hypoplastic PcomAsImprovedBoth hemispheres, unchanged
    7F50L ophthalmoplegiaLC4Balloons30Hypoplastic contralateral PcomAUnchanged–
    8F55Headache, nausea, SAHRC5Coils22CompleteCuredRight hemisphere, increased
    9F59R CN VI palsyRC4Balloons58Absent contralateral PcomAImprovedBoth hemispheres, unchanged
    10F33R CN VI palsyRC4Balloons78CompleteCured–
    11F41R ophthalmoplegiaRC4Coils22CompleteImprovedRight hemisphere, unchanged
    • Note:—FU indicates follow-up in months; Unchanged, unchanged compared with MR imaging at the time of diagnosis/directly postprocedure; R, right; L, left; COW, circle of Willis.

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American Journal of Neuroradiology: 33 (2)
American Journal of Neuroradiology
Vol. 33, Issue 2
1 Feb 2012
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S. Gevers, D. Heijtel, S.P. Ferns, P. van Ooij, W.J. van Rooij, M.J. van Osch, R. van den Berg, A.J. Nederveen, C.B. Majoie
Cerebral Perfusion Long Term after Therapeutic Occlusion of the Internal Carotid Artery in Patients Who Tolerated Angiographic Balloon Test Occlusion
American Journal of Neuroradiology Feb 2012, 33 (2) 329-335; DOI: 10.3174/ajnr.A2776

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Cerebral Perfusion Long Term after Therapeutic Occlusion of the Internal Carotid Artery in Patients Who Tolerated Angiographic Balloon Test Occlusion
S. Gevers, D. Heijtel, S.P. Ferns, P. van Ooij, W.J. van Rooij, M.J. van Osch, R. van den Berg, A.J. Nederveen, C.B. Majoie
American Journal of Neuroradiology Feb 2012, 33 (2) 329-335; DOI: 10.3174/ajnr.A2776
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  • Balloon Occlusion Tests and Therapeutic Vessel Occlusions Revisited: When, When Not, and How
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More in this TOC Section

  • Follow-up of Intracranial Aneurysms Treated by Flow Diverters: Evaluation of Parent Artery Patency Using 3D-T1 Gradient Recalled-Echo Imaging with 2-Point Dixon in Combination with 3D-TOF-MRA with Compressed Sensing
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