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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

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MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice

M. Essig, N. Anzalone, S.E. Combs, A. Dörfler, S.-K. Lee, P. Picozzi, À. Rovira, M. Weller and M. Law
American Journal of Neuroradiology May 2012, 33 (5) 803-817; DOI: https://doi.org/10.3174/ajnr.A2640
M. Essig
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N. Anzalone
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S.E. Combs
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A. Dörfler
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S.-K. Lee
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P. Picozzi
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À. Rovira
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M. Weller
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M. Law
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Abstract

SUMMARY: MR imaging is the preferred technique for the diagnosis, treatment planning, and monitoring of patients with neoplastic CNS lesions. Conventional MR imaging, with gadolinium-based contrast enhancement, is increasingly combined with advanced, functional MR imaging techniques to offer morphologic, metabolic, and physiologic information. This article provides updated recommendations to neuroradiologists, neuro-oncologists, neurosurgeons, and radiation oncologists on the practical applications of MR imaging of neoplastic CNS lesions in adults, with particular focus on gliomas, based on a review of the clinical trial evidence and personal experiences shared at a recent international meeting of experts in neuroradiology, neuro-oncology, neurosurgery, and radio-oncology.

ABBREVIATIONS:

ADC
apparent diffusion coefficient
CBV
cerebral blood volume
CNS
central nervous system
DCE
dynamic contrast-enhanced
DSC
dynamic susceptibility contrast
DTI
diffusion tensor imaging
DWI
diffusion-weighted imaging
FLAIR
fluid-attenuated inversion recovery
FSE
fast spin-echo
GFR
glomerular filtration rate
GRE
gradient recalled-echo
Ktrans
volume transfer coefficient
MRS
MR spectroscopy
PET
positron-emission tomography
PWI
perfusion-weighted imaging
rCBV
relative cerebral blood volume
TSE
turbo spin-echo
  • © 2012 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 33 (5)
American Journal of Neuroradiology
Vol. 33, Issue 5
1 May 2012
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Cite this article
M. Essig, N. Anzalone, S.E. Combs, A. Dörfler, S.-K. Lee, P. Picozzi, À. Rovira, M. Weller, M. Law
MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice
American Journal of Neuroradiology May 2012, 33 (5) 803-817; DOI: 10.3174/ajnr.A2640

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MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice
M. Essig, N. Anzalone, S.E. Combs, A. Dörfler, S.-K. Lee, P. Picozzi, À. Rovira, M. Weller, M. Law
American Journal of Neuroradiology May 2012, 33 (5) 803-817; DOI: 10.3174/ajnr.A2640
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  • Article
    • Abstract
    • ABBREVIATIONS:
    • Applications of MR Imaging in Neoplastic CNS Lesions
    • Current Limitations of MR Imaging in Neoplastic CNS Lesions
    • Protocols and Techniques for MR Imaging of Neoplastic CNS Lesions
    • Summary of Expert Meeting Recommendations
    • Footnotes
    • References
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