Article Figures & Data
Figures
- Fig 1.
A 28-year-old woman with a large TDL in the right frontal lobe. A, There is heterogeneous enhancement at the medial margin (arrows) of the lesion on the axial contrast-enhanced T1-weighted image. B and C, On the axial DWI (B) and MD map (C), the peripheral portion of the lesion shows restricted diffusion (arrows). D and E, Intralesional hyperintensities (arrow) are seen in both the lesion center (arrow) and periphery (arrowheads) on axial (D) and coronal (E) FA maps. F, Directional-coded FA map displays the directionality of these intralesional hyperintensities. The FA values are 0.06 for central nonenhancing portion and 0.21 for peripheral enhancing portion. The MD values (× 10−3 mm2/s) are 1.966 for central nonenhancing portion and 0.704 for peripheral enhancing portion.
- Fig 2.
A, A 68-year-old man with a left frontal glioblastoma, which appears as a rim-enhancing mass on the axial contrast-enhanced T1-weighted image. B and C, On the axial DWI (B) and MD map (C), restricted diffusion is present at the lesion periphery (arrow). D and E, Intralesional hyperintensities (arrow) are seen on axial (D) and coronal (E) FA maps. A red scattered ROI representing a contrast-enhancing rim is overlaid on the FA map (D). F, Note that there is a hyperintense FA rim (arrowheads in D, E, and F) in the perifocal edema, external to the enhancing rim. Directional-coded (F) FA map displays the directionality of hyperintense FA rim and intralesional hyperintensity. The FA values are 0.09 for the central nonenhancing portion and 0.13 for the peripheral enhancing portion. The MD values (× 10−3 mm2/s) are 1.530 for the central nonenhancing portion and 1.252 for the peripheral enhancing portion.
Tables
Imaging Signs TDLs High-Grade Gliomas P Value OR SEN SPE Accuracy Intralesional hyperintensities on FA maps 6 (75%) 4 (30.8%) .049 6.8 75% 69.2% 71.4% Restricted diffusion in lesion periphery 7 (87.5%) 7 (53.8%) .112 Perilesional hyperintense FA rim 1 (12.5%) 12 (92.3%) <.001 84 92.3% 87.5% 90.4% -
Note:—OR indicates odds ratio; SEN, sensitivity; SPE, specificity.
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Region/Metrics TDLs High-Grade Gliomas P Value 95% CI Nonenhancing portion FA 0.06 ± 0.02 0.07 ± 0.03 .526 −0.035–0.018 MD 1.702 ± 0.414 1.806 ± 0.578 .663 −0.597–0.388 Enhancing portion FA 0.18 ± 0.05 0.12 ± 0.01 .004 0.020-.088 MD 0.887 ± 0.265 1.237 ± 0.124 .001 −0.528–0.172 Perilesional edema FA 0.11 ± 0.01 0.17 ± 0.03 .001 −0.091–0.028 MD 1.411 ± 0.262 1.270 ± 0.121 .158 −0.062–0.346 -
Note:—CI indicates confidence interval.
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↵a Data are the mean. Unit is × 10−3 mm2/s for MD values.
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