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Research ArticleBrain
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Effects of Perianeurysmal Environment during the Growth of Cerebral Aneurysms: A Case Study

D.M. Sforza, C.M. Putman, S. Tateshima, F. Viñuela and J.R. Cebral
American Journal of Neuroradiology June 2012, 33 (6) 1115-1120; DOI: https://doi.org/10.3174/ajnr.A2908
D.M. Sforza
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C.M. Putman
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S. Tateshima
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F. Viñuela
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J.R. Cebral
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    Fig 1.

    Top row: Longitudinal CTA images of a growing basilar artery aneurysm in contact with the bone. Bottom row: Corresponding vascular and bone models showing the geometric evolution of the aneurysm against the bone. Images are 1 year apart, from oldest (left) to newest (right). These models were aligned with respect to the bone.

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    Fig 2.

    Changes in the aneurysm and parent artery geometry as a consequence of aneurysmal growth against the bone during the longitudinal follow-up period. Note the change of curvature at the stenosis on the left vertebral artery. These models were aligned with respect to the bone to compare vascular displacement. The red model is for year 1; the yellow and orange models are for years 2 and 3, respectively; and the blue model is for year 4.

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    Fig 3.

    Regions of aneurysm deformation during its evolution from 2 viewpoints (top row: right to left view; bottom row: left to right view). Left to right columns: Superposition of geometric models corresponding to all 4 examination times aligned with respect to the parent artery, and regions of aneurysm deformation from time 1 to 2, from time 2 to 3, and from time 3 to 4. Red indicates positive displacement (outward expansion), blue indicates negative displacement (contraction), and white indicates no displacement. These models were aligned with respect to the parent artery to evaluate aneurysm deformation.

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    Fig 4.

    Hemodynamic visualizations at peak systole during aneurysm progression (LR view). Left to right: Four stages during aneurysm growth. Top to bottom: Isovelocity surfaces showing the inflow streams, velocity color-coded streamlines showing flux complexity (pink is maximum velocity, blue is minimum), and WSS distribution showing stress intensity on the wall (pink is maximum, blue is minimum).

  • Fig 5.
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    Fig 5.

    Hemodynamic visualizations at peak systole during aneurysm progression (RL view). Left to right: Four stages during aneurysm growth. Top to bottom: Isovelocity surfaces showing the inflow streams, velocity color-coded streamlines showing flux complexity (pink is maximum velocity, blue is minimum), and WSS distribution showing stress intensity on the wall (pink is maximum, blue is minimum).

  • Fig 6.
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    Fig 6.

    WSS distribution at the notch (arrow) on the distal part of the aneurysm dome at year 1. Note the green (higher WSS) region at the notch (arrow) that eventually disappeared is surrounded by blue regions (lower WSS). This strongly suggests there is growth on the high WSS region.

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American Journal of Neuroradiology: 33 (6)
American Journal of Neuroradiology
Vol. 33, Issue 6
1 Jun 2012
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Cite this article
D.M. Sforza, C.M. Putman, S. Tateshima, F. Viñuela, J.R. Cebral
Effects of Perianeurysmal Environment during the Growth of Cerebral Aneurysms: A Case Study
American Journal of Neuroradiology Jun 2012, 33 (6) 1115-1120; DOI: 10.3174/ajnr.A2908

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Effects of Perianeurysmal Environment during the Growth of Cerebral Aneurysms: A Case Study
D.M. Sforza, C.M. Putman, S. Tateshima, F. Viñuela, J.R. Cebral
American Journal of Neuroradiology Jun 2012, 33 (6) 1115-1120; DOI: 10.3174/ajnr.A2908
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