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Research ArticleBrainF

Active Bleeding in Acute Subarachnoid Hemorrhage Observed by Multiphase Dynamic-Enhanced CT

K. Suzuki, N. Tanaka, S. Morita, H. Machida, E. Ueno and H. Kasuya
American Journal of Neuroradiology August 2012, 33 (7) 1374-1379; DOI: https://doi.org/10.3174/ajnr.A2981
K. Suzuki
aFrom the Departments of Radiology (K.S., H.M., E.U.) and
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N. Tanaka
bNeurosurgery (N.T., H.K.), Tokyo Women's Medical University Medical Center East, Tokyo, Japan; and
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S. Morita
cDepartment of Diagnostic Imaging and Nuclear Medicine (S.M.), Tokyo Women's Medical University, Tokyo, Japan.
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H. Machida
aFrom the Departments of Radiology (K.S., H.M., E.U.) and
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E. Ueno
aFrom the Departments of Radiology (K.S., H.M., E.U.) and
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H. Kasuya
bNeurosurgery (N.T., H.K.), Tokyo Women's Medical University Medical Center East, Tokyo, Japan; and
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    Fig 1.

    A 64-year-old man with Claassen grade 3 and WFNS grade 5. Extravasation from the right VA was observed on a multiphase enhanced source image. We selected 4 typical phases obtained at 5, 30.2, 38.6, and 52.6 seconds from among 18-phase scans taken at 2.8-second intervals on multiphase dynamic-enhanced CT. A portion of the right VA near the union was enhanced during the early phase (A, blank arrow), and lobulated extravasation was depicted as an irregularly shaped enhancement (A, white arrow). The premedullary cistern was enhanced in the late phase. Extravasation was well depicted as a wedge-shaped enhancement extending into the subarachnoid space on an additional 4D CT image (B, dark arrow). VA dissection with active bleeding was diagnosed.

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    Fig 2.

    A 56-year-old woman with Claassen grade 3 and WFNS grade 4. There was a large aneurysm in the MCA. We selected scans obtained at 5, 24.6, 33, and 52.6 seconds, and this case showed typical findings of nebulous enhancement around an aneurysm that was associated with extravasation (A, blank arrow). Hematomas larger than those seen on plain CT were observed during the surgical clipping procedure, and premature rupture occurred intraoperatively. A follow-up plain CT obtained the following day showed increased hematoma (B).

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    Fig 3.

    A 68-year-old woman with Claassen grade 4 and WFNS grade 5. A 9-mm aneurysm was identified in the right internal carotid posterior communicating portion by CTA. Contrast extravasation at the third ventricle was suspected on the basis of a CTP source image (A). Active bleeding from an aneurysm penetrating the third ventricle was confirmed with sagittal 20-mm-thickness-slab maximum-intensity-projection images (B), and a volume-rendered image was also useful for assessing the shape of the aneurysm (C, white arrow) and the extent of bleeding (C, arrowheads). Contrast medium in the aneurysm was washed out in the delayed phase, but extravasation was not.

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    Fig 4.

    A 52-year-old man with Claassen grade 4 and WFNS grade 5. An irregularly shaped aneurysm 2 cm in diameter was identified at the anterior communicating artery on CTA. Extravasation had a vessel-like shape at the interhemispheric cistern (A, arrow), and spreading contrast extravasation was observed in the left ventricle (B, arrow). On the reconstructed 4D CT images, the aneurysm showed early enhancement and delayed washout (C, arrow), and string-shaped extravasation from the aneurysm penetrated from the interhemispheric cistern into left lateral ventricle without washout (C, arrowheads). Extravasation of contrast medium was also observed on angiography performed in preparation for a coiling procedure. Follow-up CT after 6 hours indicated enlargement of the hematoma.

Tables

  • Figures
  • Characteristics of patients with and without active bleeding

    FactorActive Bleeding at Initial CT PerfusionP
    With BleedingWithout Bleeding
    Sex.323
        Male316
        Female1022
    Average age (yr)65.862.9.754
    Aneurysm location.154
        ICA211
        ACA317
        MCA45
        VA/BA45
    Claassen gradea.023
        1, 2012
        3, 41326
    WFNS gradea.023
        1, 2012
        3, 4, 51326
    Hours from onseta.007
        ∼21115
        >2013
        Unknown210
    Surgical repair of aneurysm (clip/coil)725.515
    Follow-up CT performed1033.404
    Increased amount of hemorrhagea75.002
    Death within 14 days after admission815.207
    Total1338
    • ↵a Items differ significantly between the 2 patient groups.

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American Journal of Neuroradiology: 33 (7)
American Journal of Neuroradiology
Vol. 33, Issue 7
1 Aug 2012
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Cite this article
K. Suzuki, N. Tanaka, S. Morita, H. Machida, E. Ueno, H. Kasuya
Active Bleeding in Acute Subarachnoid Hemorrhage Observed by Multiphase Dynamic-Enhanced CT
American Journal of Neuroradiology Aug 2012, 33 (7) 1374-1379; DOI: 10.3174/ajnr.A2981

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Active Bleeding in Acute Subarachnoid Hemorrhage Observed by Multiphase Dynamic-Enhanced CT
K. Suzuki, N. Tanaka, S. Morita, H. Machida, E. Ueno, H. Kasuya
American Journal of Neuroradiology Aug 2012, 33 (7) 1374-1379; DOI: 10.3174/ajnr.A2981
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