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Research ArticleInterventional

Recanalization of Large Intracranial Vessels Using the Penumbra System: A Single-Center Experience

M.-N. Psychogios, A. Kreusch, K. Wasser, A. Mohr, K. Gröschel and M. Knauth
American Journal of Neuroradiology September 2012, 33 (8) 1488-1493; DOI: https://doi.org/10.3174/ajnr.A2990
M.-N. Psychogios
aFrom the Departments of Neuroradiology (M.-N.P., A.K., A.M., M.K.)
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A. Kreusch
aFrom the Departments of Neuroradiology (M.-N.P., A.K., A.M., M.K.)
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K. Wasser
bNeurology (K.W., K.G.), University Medicine Goettingen, Goettingen, Germany.
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A. Mohr
aFrom the Departments of Neuroradiology (M.-N.P., A.K., A.M., M.K.)
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K. Gröschel
bNeurology (K.W., K.G.), University Medicine Goettingen, Goettingen, Germany.
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M. Knauth
aFrom the Departments of Neuroradiology (M.-N.P., A.K., A.M., M.K.)
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    Fig 1.

    A 36-year-old woman with an acute left hemiparesis and an admission mRS of 5. A and B, Noncontrast CT scan shows subtle low attenuation in the right putamen and head of the caudate nucleus; CT perfusion shows a significant reduction of cerebral blood flow in the right MCA territory. C, After initiation of IV-rtPA, the patient was transferred to the angiography suite and a persistent occlusion (TICI 0) of the M1 segment of the right MCA is shown on the posteroanterior angiogram. D, Successful recanalization (TICI 3) was achieved after thrombus aspiration with the PS. Total time from symptom onset to successful recanalization was 205 minutes. The patient was discharged to the rehabilitation unit with an mRS score of 4 after 11 days, and a favorable outcome with an mRS score of 2 was diagnosed at follow-up.

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    Fig 2.

    Chart showing the follow-up outcome (mRS) of 91 patients treated with the PS (upper bar) and the outcomes within the various categories in the population. The figures in the bars indicate the percentage of patients with a favorable outcome at follow-up.

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    CountPartial or Complete Reperfusion (TICI 2–3)Favorable Outcome on Follow-Up (mRS ≤ 2)
    PS only1411 (79%)7/14 (50%)
    IV-rtPA + PS106 (60%)0/8a (0%)
    IA-rtPA + PS2723 (85%)6/22a (27%)
    IV + IA-rtPA + PS4030 (75%)11/36a (31%)
    • ↵a A total of 11 patients were lost to follow-up.

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American Journal of Neuroradiology: 33 (8)
American Journal of Neuroradiology
Vol. 33, Issue 8
1 Sep 2012
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M.-N. Psychogios, A. Kreusch, K. Wasser, A. Mohr, K. Gröschel, M. Knauth
Recanalization of Large Intracranial Vessels Using the Penumbra System: A Single-Center Experience
American Journal of Neuroradiology Sep 2012, 33 (8) 1488-1493; DOI: 10.3174/ajnr.A2990

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Recanalization of Large Intracranial Vessels Using the Penumbra System: A Single-Center Experience
M.-N. Psychogios, A. Kreusch, K. Wasser, A. Mohr, K. Gröschel, M. Knauth
American Journal of Neuroradiology Sep 2012, 33 (8) 1488-1493; DOI: 10.3174/ajnr.A2990
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