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Research ArticleBrain
Open Access

The Impact of Lesion In-Painting and Registration Methods on Voxel-Based Morphometry in Detecting Regional Cerebral Gray Matter Atrophy in Multiple Sclerosis

A. Ceccarelli, J.S. Jackson, S. Tauhid, A. Arora, J. Gorky, E. Dell'Oglio, A. Bakshi, T. Chitnis, S.J. Khoury, H.L. Weiner, C.R.G. Guttmann, R. Bakshi and M. Neema
American Journal of Neuroradiology September 2012, 33 (8) 1579-1585; DOI: https://doi.org/10.3174/ajnr.A3083
A. Ceccarelli
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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J.S. Jackson
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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S. Tauhid
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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A. Arora
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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J. Gorky
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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E. Dell'Oglio
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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A. Bakshi
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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T. Chitnis
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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S.J. Khoury
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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H.L. Weiner
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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C.R.G. Guttmann
bRadiology (C.R.G.G.), Brigham and Women's Hospital, Laboratory for Neuroimaging Research, Partners MS Center, Harvard Medical School, Boston, Massachusetts.
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R. Bakshi
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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M. Neema
aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
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Article Information

vol. 33 no. 8 1579-1585
DOI 
https://doi.org/10.3174/ajnr.A3083
PubMed 
22460341

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received September 28, 2011
  • Accepted after revision November 16, 2011
  • Published online September 10, 2012.

Copyright & Usage 
© 2012 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. A. Ceccarellia,
  2. J.S. Jacksona,
  3. S. Tauhida,
  4. A. Aroraa,
  5. J. Gorkya,
  6. E. Dell'Oglioa,
  7. A. Bakshia,
  8. T. Chitnisa,
  9. S.J. Khourya,
  10. H.L. Weinera,
  11. C.R.G. Guttmannb,
  12. R. Bakshia and
  13. M. Neemaa
  1. aFrom the Departments of Neurology (A.C., J.S.J., S.T., A.A., J.G., E.D., A.B., T.C., S.J.K., H.L.W., R.B., M.N.)
  2. bRadiology (C.R.G.G.), Brigham and Women's Hospital, Laboratory for Neuroimaging Research, Partners MS Center, Harvard Medical School, Boston, Massachusetts.
  1. Please address correspondence to Mohit Neema, MD, Brigham and Women's Hospital, Harvard Medical School, Laboratory for Neuroimaging Research, One Brookline Place, Suite 602, Brookline, MA 02445; e-mail: mneema{at}bwh.harvard.edu
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American Journal of Neuroradiology: 33 (8)
American Journal of Neuroradiology
Vol. 33, Issue 8
1 Sep 2012
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A. Ceccarelli, J.S. Jackson, S. Tauhid, A. Arora, J. Gorky, E. Dell'Oglio, A. Bakshi, T. Chitnis, S.J. Khoury, H.L. Weiner, C.R.G. Guttmann, R. Bakshi, M. Neema
The Impact of Lesion In-Painting and Registration Methods on Voxel-Based Morphometry in Detecting Regional Cerebral Gray Matter Atrophy in Multiple Sclerosis
American Journal of Neuroradiology Sep 2012, 33 (8) 1579-1585; DOI: 10.3174/ajnr.A3083

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The Impact of Lesion In-Painting and Registration Methods on Voxel-Based Morphometry in Detecting Regional Cerebral Gray Matter Atrophy in Multiple Sclerosis
A. Ceccarelli, J.S. Jackson, S. Tauhid, A. Arora, J. Gorky, E. Dell'Oglio, A. Bakshi, T. Chitnis, S.J. Khoury, H.L. Weiner, C.R.G. Guttmann, R. Bakshi, M. Neema
American Journal of Neuroradiology Sep 2012, 33 (8) 1579-1585; DOI: 10.3174/ajnr.A3083
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