Article Figures & Data
Figures
- Fig 1.
A, AP view of color-coded right carotid artery DSA of a control subject. Arterial region of interest: I1, cervical portion of ICA; I2, cavernous portion of ICA; I3, supraclinoid portion of ICA; A1, the midpoint of the first portion of ACA; M1, the midpoint of the first segment of MCA; and M3, the point immediately after the turning junction of the second and third segment of MCA. The venous region of interest: IJV is located at a point 2 cm below its junction with SS, and MCV at the midpoint of the ascending limb of MCV. B, Time-attenuation curves of the 8 ROIs on AP view (horizontal axis: imaging timeline of DSA in sec; vertical axis: contrast medium opacification). The time point of maximum contrast medium opacification of each curve is defined as the Tmax of each region of interest.
- Fig 2.
A, Lateral view of a color-coded right carotid artery DSA of a control subject. Arterial region of interest: IA, cervical portion of ICA; IB, cavernous portion of ICA; IC, supraclinoid portion of ICA; A2, the midpoint of the second portion of ACA; A3, a point in the proximal segment of pericallosal artery; and M2, a point in the proximal temporal branch of MCA before its bifurcation. The venous region of interest of FV, PV, and OV are designated at just before their entry to SSS; SSS, a point located 2 cm above the torcular herophili; SS, the midpoint of sigmoid sinus. B, Time-attenuation curves of the 12 ROIs on lateral view.
- Fig 3.
The ROC curves of rTmax values at 7 different arterial ROIs.
- Fig 4.
A, Lateral view of color-coded left carotid artery DSA of a 78-year-old man with 90% stenosis of the left proximal ICA. Before stent placement, 5 ROIs were selected in the following order: cervical portion of ICA (IA), cavernous portion of ICA (IB), the second portion of ACA (A2), the temporal branch of MCA (M2), and SSS. B, Time-attenuation curves of the selected ROIs in A. C, Lateral view of the color-coded left carotid artery DSA of the same patient after stent placement. The same 5 selected ROIs as in A. D, After stent placement, the time-attenuation curves of the arterial ROIs become steeper and their Tmax values shorter, whereas no interval change of the waveform of SSS is evident compared with the corresponding waveform before stent placement in B.
Tables
ROI ICC (95% CI) AP view ICA-AP 0.680 (0.408, 0.841) A1 0.620 (0.169, 0.856) M1 0.560 (0.232, 0.773) M3 0.580 (0.260, 0.785) MCV 0.320 (0.086, 0.542) JV 0.310 (−0.084, 0.620) Lateral view ICA-LAT 0.410 (0.040, 0.681) OphA 0.610 (0.295, 0.805) A2 0.430 (0.186, 0.639) A3 0.460 (−0.216, 0.838) M2 0.460 (0.101, 0.713) FV 0.22 (−0.295, 0.466) PV 0.480 (−0.192, 0.846) OV 0.310 (0.108, 0.391) SSS 0.330 (−0.178, 0.665) SS 0.320 (−0.073, 0.627) - Table 2:
Comparison of the average rTmax of each ROI in patients with carotid stenosis versus the control group
Patient Group(Prestenting, n = 25) Control Group (n = 34) P Value AP view ICA-AP 0.35 ± 0.31 0.12 ± 0.11 0.01* A1 0.54 ± 0.39 (n = 15) 0.28 ± 0.28 0.01* M1 0.72 ± 0.41 0.40 ± 0.32 P < 0.001* M3 1.05 ± 0.41 0.80 ± 0.37 0.12 MCV 3.79 ± 2.04 3.86 ± 1.70 0.23 IJV 6.83 ± 1.11 6.81 ± 1.25 0.45 Lateral view ICA-LAT 0.23 ± 0.25 0.10 ± 0.11 0.002* OphA 0.97 ± 0.67 0.35 ± 0.22 P < 0.001* A2 0.86 ± 0.68 (n = 15) 0.53 ± 0.35 0.01* A3 1.03 ± 0.62 (n = 15) 0.81 ± 0.40 0.06 M2 1.31 ± 0.59 0.95 ± 0.36 0.002* FV 5.12 ± 1.4 4.83 ± 0.93 0.17 PV 5.41 ± 0.87 5.11 ± 1.00 0.35 OV 5.36 ± 1.41 5.17 ± 1.01 0.27 SSS 6.28 ± 1.60 6.16 ± 1.14 0.37 SS 6.64 ± 1.56 6.51 ± 1.10 0.4 -
↵* Statistically significant (P < .05).
-
ROI AUC(95%CI) P value Optimal Cutoff Value Sensitivity Specificity PPV NPV ICA-AP 0.686(0.527–0.844) 0.021 0.340 44.4% 94.1% 80.0% 76.2% A1 0.609(0.417–0.802) 0.260 0.840 16.7% 100.0% 100.0% 76.2% M1 0.759(0.627–0.891) 0.0001 0.340 94.4% 50.0% 50.0% 94.4% ICA-LAT 0.716(0.561–0.870) 0.006 0.267 44.4% 94.1% 80.0% 76.2% OphA 0.890(0.802–0.977) <.0001 0.670 66.7% 91.2% 80.0% 83.8% A2 0.698(0.520–0.876) 0.030 1.000 50.0% 93.8% 75.0% 83.3% M2 0.754(0.617–0.891) 0.0003 0.840 88.9% 47.1% 47.1% 88.9% -
Note.—NPV, negative predictive value; PPV, positive predictive value.
-
- Table 4:
Comparison of the average rTmax of each ROI in patients with carotid stenosis before and after stenting
Before Stenting (n = 25) After Stenting (n = 25) P Value AP view ICA-AP 0.35 ± 0.31 0.17 ± 0.22 0.002* A1 0.54 ± 0.39 (n = 15) 0.49 ± 0.44 0.28 M1 0.72 ± 0.41 0.53 ± 0.39 0.01* M3 1.05 ± 0.41 1.18 ± 1.58 0.33 IJV 6.83 ± 1.11 6.58 ± 1.35 0.38 MCV 3.79 ± 2.04 3.75 ± 1.50 0.47 Lateral view ICA-LAT 0.23 ± 0.25 0.11 ± 0.15 0.01* OphA 0.97 ± 0.67 0.54 ± 0.54 0.01* A2 0.86 ± 0.68 (n = 15) 0.53 ± 0.48 0.01* A3 1.03 ± 0.62 (n = 15) 0.84 ± 0.50 0.02* M2 1.31 ± 0.59 1.07 ± 0.55 0.03* FV 5.12 ± 1.4 4.84 ± 1.25 0.22 PV 5.41 ± 0.87 4.89 ± 1.28 0.18 OV 5.36 ± 1.41 4.88 ± 1.21 0.11 SSS 6.28 ± 1.60 6.04 ± 2.12 0.31 SS 6.64 ± 1.56 6.25 ± 2.10 0.40 -
↵* Statistically significant (p < 0.05).
-
In this issue
Jump to section
Related Articles
Cited By...
- Association of intracranial arteriovenous malformation embolization with more rapid rate of perfusion in the peri-nidal region on color-coded quantitative digital subtraction angiography
- Intracranial venous sinus stenosis: hemodynamic assessment with two-dimensional parametric parenchymal blood flow software on digital subtraction angiography
- Validating the Automatic Independent Component Analysis of DSA
- Prediction of hyperperfusion phenomenon after carotid artery stenting and carotid angioplasty using quantitative DSA with cerebral circulation time imaging
- Prolonged cerebral circulation time is more associated with symptomatic carotid stenosis than stenosis degree or collateral circulation
- Validation of cerebral arteriovenous malformation hemodynamics assessed by DSA using quantitative magnetic resonance angiography: preliminary study
- Quantifying the Cerebral Hemodynamics of Dural Arteriovenous Fistula in Transverse Sigmoid Sinus Complicated by Sinus Stenosis: A Retrospective Cohort Study
- Peritherapeutic Hemodynamic Changes of Carotid Stenting Evaluated with Quantitative DSA in Patients with Carotid Stenosis
- Changes of Time-Attenuation Curve Blood Flow Parameters in Patients with and without Carotid Stenosis
- Exploring the Value of Using Color-Coded Quantitative DSA Evaluation on Bilateral Common Carotid Arteries in Predicting the Reliability of Intra-Ascending Aorta Flat Detector CT-CBV Maps
- Stenotic Transverse Sinus Predisposes to Poststenting Hyperperfusion Syndrome as Evidenced by Quantitative Analysis of Peritherapeutic Cerebral Circulation Time
- 4D Digital Subtraction Angiography: Implementation and Demonstration of Feasibility
- Can Iterative Reconstruction Improve Imaging Quality for Lower Radiation CT Perfusion? Initial Experience