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Research ArticleBrain
Open Access

C-Arm CT Measurement of Cerebral Blood Volume and Cerebral Blood Flow Using a Novel High-Speed Acquisition and a Single Intravenous Contrast Injection

K. Royalty, M. Manhart, K. Pulfer, Y. Deuerling-Zheng, C. Strother, A. Fieselmann and D. Consigny
American Journal of Neuroradiology November 2013, 34 (11) 2131-2138; DOI: https://doi.org/10.3174/ajnr.A3536
K. Royalty
aFrom the Department of Biomedical Engineering (K.R.)
cSiemens Medical Solutions USA (K.R.), Hoffman Estates, Illinois
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M. Manhart
dPattern Recognition Lab (M.M.), Friedrich-Alexander University, Erlangen, Germany
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K. Pulfer
bSchool of Medicine and Public Health (K.P., C.S., D.C.), University of Wisconsin, Madison, Wisconsin
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Y. Deuerling-Zheng
eSiemens AG, Healthcare Sector (Y.D.-Z., A.F.), Forchheim, Germany.
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C. Strother
bSchool of Medicine and Public Health (K.P., C.S., D.C.), University of Wisconsin, Madison, Wisconsin
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A. Fieselmann
eSiemens AG, Healthcare Sector (Y.D.-Z., A.F.), Forchheim, Germany.
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D. Consigny
bSchool of Medicine and Public Health (K.P., C.S., D.C.), University of Wisconsin, Madison, Wisconsin
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REFERENCES

  1. 1.↵
    1. Lees KR,
    2. Hankey GJ,
    3. Hacke W
    . Design of future acute-stroke treatment trials. Lancet Neurol 2003;2:54–61
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Struffert T,
    2. Deuerling-Zheng Y,
    3. Kloska S,
    4. et al
    . Cerebral blood volume imaging by flat detector computed tomography in comparison to conventional multislice perfusion CT. Eur Radiol 2010;21:882–89
    PubMed
  3. 3.↵
    1. Struffert T,
    2. Deuerling-Zheng Y,
    3. Kloska S,
    4. et al
    . Flat detector CT in the evaluation of brain parenchyma, intracranial vasculature, and cerebral blood volume: a pilot study in patients with acute symptoms of cerebral ischemia. AJNR Am J Neuroradiol 2010;31:1462–69
    Abstract/FREE Full Text
  4. 4.↵
    1. Ahmed AS,
    2. Zellerhoff M,
    3. Strother CM,
    4. et al
    . C-arm CT measurement of cerebral blood volume: an experimental study in canines. AJNR Am J Neuroradiol 2009;30:917–22
    Abstract/FREE Full Text
  5. 5.↵
    1. Bley T,
    2. Strother CM,
    3. Pulfer K,
    4. et al
    . C-arm CT measurement of cerebral blood volume in ischemic stroke: an experimental study in canines. AJNR Am J Neuroradiol 2010;31:536–40
    Abstract/FREE Full Text
  6. 6.↵
    1. Yasuda R,
    2. Royalty K,
    3. Pulfer K,
    4. et al
    . C-arm CT measurement of cerebral blood volume using intra-arterial injection of contrast medium: an experimental study in canines. AJNR Am J Neuroradiol 2012;33:1696–1701
    Abstract/FREE Full Text
  7. 7.↵
    1. Wintermark M,
    2. Smith WS,
    3. Ko NU,
    4. et al
    . Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients. AJNR Am J Neuroradiol 2004;25:720–29
    Abstract/FREE Full Text
  8. 8.↵
    1. Ganguly A,
    2. Fieselmann A,
    3. Marks M,
    4. et al
    . Cerebral CT perfusion using an interventional C-arm imaging system: cerebral blood flow measurements. AJNR Am J Neuroradiol 2011;32:1525–31
    Abstract/FREE Full Text
  9. 9.↵
    1. Mordasini P,
    2. El-Koussy M,
    3. Brekenfeld C,
    4. et al
    . Applicability of tableside flat panel detector CT parenchymal cerebral blood volume measurement in neurovascular interventions: preliminary clinical experience. AJNR Am J Neuroradiol 2011;33:154–58
    PubMed
  10. 10.↵
    1. Zellerhoff M,
    2. Deuerling-Zheng Y,
    3. Strother CM,
    4. et al
    . Measurement of cerebral blood volume using angiographic C-arm systems. Proc. SPIE 7262, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, 72620H (February 27, 2009)
  11. 11.↵
    1. Van der Bom IMJ,
    2. Mehra M,
    3. Walvick RP,
    4. et al
    . Quantitative evaluation of C-Arm CT cerebral blood volume in a canine model of ischemic stroke. AJNR Am J Neuroradiol 2012;33:353-58
    Abstract/FREE Full Text
  12. 12.↵
    1. Fieselmann A,
    2. Ganguly A,
    3. Deuerling-Zheng Y,
    4. et al
    . A dynamic reconstruction approach for cerebral blood flow quantification with an interventional C-arm CT. 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro 2010:53–56
  13. 13.↵
    1. Fieselmann A,
    2. Ganguly A,
    3. Deuerling-Zheng Y,
    4. et al
    . Interventional 4-D C-arm CT perfusion imaging using interleaved scanning and partial reconstruction interpolation. IEEE Trans Med Imaging 2012;31:892–906
    CrossRefPubMed
  14. 14.↵
    1. Kudo K,
    2. Sasaki M,
    3. Yamada K,
    4. et al
    . Differences in CT perfusion maps generated by different commercial software: quantitative analysis by using identical source data of acute stroke patients. Radiology 2010;254:200–09
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Konstas AA,
    2. Goldmakher GV,
    3. Lee TY,
    4. et al
    . Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: technical implementations. AJNR Am J Neuroradiol 2009;30:885–92
    Abstract/FREE Full Text
  16. 16.↵
    1. Wellens D,
    2. Wouters L,
    3. De Reese R,
    4. et al
    . The cerebral blood distribution in dogs and cats: an anatomical and functional study. Brain Res 1975;86:429–38
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Vierra AJ,
    2. Garrett JM
    . Understanding interobserver agreement: the kappa statistic. Fam Med 2005;37:360–61
    PubMedWeb of Science
  18. 18.↵
    1. Feinstein AR,
    2. Cicchetti DV
    . High agreement but low kappa: I. The problems of two paradoxes. J Clin Epidemiol 1990;43:543–49
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Struffert T,
    2. Richter G,
    3. Engelhorn T,
    4. et al
    . Visualisation of intracerebral haemorrhage with flat-detector CT compared to multislice CT: results in 44 cases. Eur Radiol 2009;19:619–25
    PubMed
  20. 20.↵
    1. Kalender WA
    . Der Einsatz von Flachbilddetektoren für die CT-Bildgebung. Der Radiologe 2003;43:379–87
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Loose R,
    2. Wucherer M,
    3. Brunner T
    . Visualization of 3D low contrast objects by CT cone-beam reconstruction of a rotational angiography with a dynamic solid body detector. RoFo 2005;S1:PO 160
  22. 22.↵
    1. Silvennoinen HM,
    2. Hamberg LM,
    3. Valanne L,
    4. et al
    . Increasing contrast agent concentration improves enhancement in first-pass CT perfusion. AJNR Am J Neuroradiol 2007;28:1299–303
    Abstract/FREE Full Text
  23. 23.↵
    1. Manduca A,
    2. Yu L,
    3. Trzasko JD,
    4. et al
    . Projection space denoising with bilateral filtering and CT noise modeling for dose reduction in CT. Med Phys 2009;36:4911–19
    CrossRefPubMed
  24. 24.↵
    1. Supanich M,
    2. Tao Y,
    3. Nett B,
    4. et al
    . Radiation dose reduction in time-resolved CT angiography using highly constrained back projection reconstruction. Phys Med Biol 2009;54:4575–93
    CrossRefPubMed
  25. 25.↵
    1. Nett BE,
    2. Brauweiler R,
    3. Kalender W,
    4. et al
    . Perfusion measurements by micro-CT using prior image constrained compressed sensing (PICCS): initial phantom results. Phys Med Biol 2010;55:2333–50
    CrossRefPubMed
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Cite this article
K. Royalty, M. Manhart, K. Pulfer, Y. Deuerling-Zheng, C. Strother, A. Fieselmann, D. Consigny
C-Arm CT Measurement of Cerebral Blood Volume and Cerebral Blood Flow Using a Novel High-Speed Acquisition and a Single Intravenous Contrast Injection
American Journal of Neuroradiology Nov 2013, 34 (11) 2131-2138; DOI: 10.3174/ajnr.A3536

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C-Arm CT Measurement of Cerebral Blood Volume and Cerebral Blood Flow Using a Novel High-Speed Acquisition and a Single Intravenous Contrast Injection
K. Royalty, M. Manhart, K. Pulfer, Y. Deuerling-Zheng, C. Strother, A. Fieselmann, D. Consigny
American Journal of Neuroradiology Nov 2013, 34 (11) 2131-2138; DOI: 10.3174/ajnr.A3536
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  • Evaluation of Collaterals and Clot Burden Using Time-Resolved C-Arm Conebeam CT Angiography in the Angiography Suite: A Feasibility Study
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  • Time-Resolved C-Arm Computed Tomographic Angiography Derived From Computed Tomographic Perfusion Acquisition: New Capability for One-Stop-Shop Acute Ischemic Stroke Treatment in the Angiosuite
  • Dynamic Angiography and Perfusion Imaging Using Flat Detector CT in the Angiography Suite: A Pilot Study in Patients with Acute Middle Cerebral Artery Occlusions
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