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Research ArticlePediatric Neuroimaging
Open Access

Diffusion Tensor Imaging Properties and Neurobehavioral Outcomes in Children with Hydrocephalus

W. Yuan, R.C. McKinstry, J.S. Shimony, M. Altaye, S.K. Powell, J.M. Phillips, D.D. Limbrick, S.K. Holland, B.V. Jones, A. Rajagopal, S. Simpson, D. Mercer and F.T. Mangano
American Journal of Neuroradiology February 2013, 34 (2) 439-445; DOI: https://doi.org/10.3174/ajnr.A3218
W. Yuan
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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R.C. McKinstry
fMallinckrodt Institute of Radiology (R.C.M., J.S.S.)
iWashington University School of Medicine (R.C.M., J.S.S., S.K.P., D.D.L., D.M.), Washington University, St. Louis, Missouri
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J.S. Shimony
fMallinckrodt Institute of Radiology (R.C.M., J.S.S.)
iWashington University School of Medicine (R.C.M., J.S.S., S.K.P., D.D.L., D.M.), Washington University, St. Louis, Missouri
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M. Altaye
bDivision of Biostatistics and Epidemiology (M.A.)
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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S.K. Powell
gDepartment of Neurology (S.K.P.)
iWashington University School of Medicine (R.C.M., J.S.S., S.K.P., D.D.L., D.M.), Washington University, St. Louis, Missouri
jDepartment of Psychology (S.K.P.), St. Louis Children's Hospital, St. Louis, Missouri.
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J.M. Phillips
cDivision of Developmental and Behavioral Pediatrics-Psychology (J.M.P.)
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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D.D. Limbrick Jr
hDepartment of Neurological Surgery (D.D.L., D.M.)
iWashington University School of Medicine (R.C.M., J.S.S., S.K.P., D.D.L., D.M.), Washington University, St. Louis, Missouri
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S.K. Holland
aFrom the Department of Radiology (W.Y., S.K.H., B.V.J., A.R., S.S.)
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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B.V. Jones
aFrom the Department of Radiology (W.Y., S.K.H., B.V.J., A.R., S.S.)
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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A. Rajagopal
aFrom the Department of Radiology (W.Y., S.K.H., B.V.J., A.R., S.S.)
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S. Simpson
aFrom the Department of Radiology (W.Y., S.K.H., B.V.J., A.R., S.S.)
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D. Mercer
hDepartment of Neurological Surgery (D.D.L., D.M.)
iWashington University School of Medicine (R.C.M., J.S.S., S.K.P., D.D.L., D.M.), Washington University, St. Louis, Missouri
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F.T. Mangano
dDivision of Pediatric Neurosurgery (F.T.M.), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
eUniversity of Cincinnati College of Medicine (W.Y., M.A., J.M.P., S.K.H., B.V.J., F.T.M.), Cincinnati, Ohio
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References

  1. 1.↵
    1. Del Bigio MR,
    2. Wilson MJ,
    3. Enno T
    . Chronic hydrocephalus in rats and humans: white matter loss and behavior changes. Ann Neurol 2003;53:337–46
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Del Bigio MR,
    2. Zhang YW
    . Cell death, axonal damage, and cell birth in the immature rat brain following induction of hydrocephalus. Exp Neurol 1998;154:57–69
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Fletcher JM,
    2. Bohan TP,
    3. Brandt ME,
    4. et al
    . Cerebral white matter and cognition in hydrocephalic children. Arch Neurol 1992;49:818–24
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Fletcher JM,
    2. McCauley SR,
    3. Brandt ME,
    4. et al
    . Regional brain tissue composition in children with hydrocephalus: relationships with cognitive development. Arch Neurol 1996;53:549–57
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Hannay HJ
    . Functioning of the corpus callosum in children with early hydrocephalus. J Int Neuropsychol Soc 2000;6:351–61
    CrossRefPubMed
  6. 6.↵
    1. Khan OH,
    2. Enno TL,
    3. Del Bigio MR
    . Brain damage in neonatal rats following kaolin induction of hydrocephalus. Exp Neurol 2006;200:311–20
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Zimmerman RD,
    2. Fleming CA,
    3. Lee BC,
    4. et al
    . Periventricular hyperintensity as seen by magnetic resonance: prevalence and significance. AJR Am J Roentgenol 1986;146:443–50
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Bradley WG Jr.
    . MR prediction of shunt response in NPH: CSF morphology versus physiology. AJNR Am J Neuroradiol 1998;19:1285–86
    PubMed
  9. 9.↵
    1. Assaf Y,
    2. Ben-Sira L,
    3. Constantini S,
    4. et al
    . Diffusion tensor imaging in hydrocephalus: initial experience. AJNR Am J Neuroradiol 2006;27:1717–24
    Abstract/FREE Full Text
  10. 10.↵
    1. Hasan KM,
    2. Eluvathingal TJ,
    3. Kramer LA,
    4. et al
    . White matter microstructural abnormalities in children with spina bifida myelomeningocele and hydrocephalus: a diffusion tensor tractography study of the association pathways. J Magn Reson Imaging 2008;27:700–09
    CrossRefPubMed
  11. 11.↵
    1. Herweh C,
    2. Akbar M,
    3. Wengenroth M,
    4. et al
    . DTI of commissural fibers in patients with Chiari II-malformation. Neuroimage 2009;44:306–11
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Yuan W,
    2. Mangano FT,
    3. Air EL,
    4. et al
    . Anisotropic diffusion properties in infants with hydrocephalus: a diffusion tensor imaging study. AJNR Am J Neuroradiol 2009;30:1792–98
    Abstract/FREE Full Text
  13. 13.↵
    1. Air EL,
    2. Yuan W,
    3. Holland SK,
    4. et al
    . Longitudinal comparison of pre- and postoperative diffusion tensor imaging parameters in young children with hydrocephalus. J Neurosurg Pediatr 2010;5:385–91
    CrossRefPubMed
  14. 14.↵
    1. Harrison PL,
    2. Oakland T
    . Adaptive Behavior Assessment System. 2nd ed, San Antonio, Texas: Harcourt Assessment; 2003
  15. 15.↵
    1. Jiang H,
    2. van Zijl PC,
    3. Kim J,
    4. et al
    . DTIStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed 2006;81:106–16
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Woods RP,
    2. Grafton ST,
    3. Watson JD,
    4. et al
    . Automated image registration. II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr 1998;22:153–65
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Basser PJ,
    2. Pierpaoli C
    . A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med 1998;39:928–34
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Hermoye L,
    2. Saint-Martin C,
    3. Cosnard G,
    4. et al
    . Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood. Neuroimage 2006;15 29:493–504
  19. 19.↵
    1. Yuan W,
    2. HS,
    3. Shimony JS,
    4. Jones BV,
    5. et al
    . Quality assurance in multi-institution and multi-scanner MRI neuroimaging research. In: Proceedings of the 6th Congress and Exhibition of the Joint Societies of Paediatric Radiology, London, UK. May 27–31, 2011
  20. 20.↵
    1. Kruggel F,
    2. Turner J,
    3. Muftuler LT
    . Impact of scanner hardware and imaging protocol on image quality and compartment volume precision in the ADNI cohort. Neuroimage 2010; 49:2123–33
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Colombo P,
    2. Baldassarri A,
    3. Del Corona M,
    4. et al
    . Multicenter trial for the set-up of a MRI quality assurance programme. Magn Reson Imaging 2004;22:93–101
    CrossRefPubMed
  22. 22.↵
    1. Van Horn JD,
    2. Toga AW
    . Multisite neuroimaging trials. Current Opin Neurol 2009;22:370–78
    CrossRefPubMed
  23. 23.↵
    1. Uluğ AM,
    2. Truong TN,
    3. Filippi CG,
    4. et al
    . Diffusion imaging in obstructive hydrocephalus. AJNR Am J Neuroradiol 2003;24:1171–76
    Abstract/FREE Full Text
  24. 24.↵
    1. Leliefeld PH,
    2. Gooskens RH,
    3. Tulleken CA,
    4. et al
    . Noninvasive detection of the distinction between progressive and compensated hydrocephalus in infants: is it possible? J Neurosurg Pediatr 2010;5:562–68
    CrossRefPubMed
  25. 25.↵
    1. Del Bigio MR,
    2. Slobodian I,
    3. Schellenberg AE,
    4. et al
    . Magnetic resonance imaging indicators of blood-brain barrier and brain water changes in young rats with kaolin-induced hydrocephalus. Fluids Barriers CNS 2011;8:22
    CrossRefPubMed
  26. 26.↵
    1. Song SK,
    2. Sun SW,
    3. Ramsbottom MJ,
    4. et al
    . Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002;17:1429–36
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Song SK,
    2. Yoshino J,
    3. Le TQ,
    4. et al
    . Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage 2005;26:132–40
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Budde MD,
    2. Kim JH,
    3. Liang HF,
    4. et al
    . Axonal injury detected by in vivo diffusion tensor imaging correlates with neurological disability in a mouse model of multiple sclerosis. NMR Biomed 2008;21:589–97
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Goebell E,
    2. Paustenbach S,
    3. Vaeterlein O,
    4. et al
    . Low-grade and anaplastic gliomas: differences in architecture evaluated with diffusion-tensor MR imaging. Radiology 2006;239:217–22
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Mataró M,
    2. Junque C,
    3. Poca MA,
    4. et al
    . Neuropsychological findings in congenital and acquired childhood hydrocephalus. Neuropsychol Rev 2001;11:169–78
    CrossRefPubMedWeb of Science
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Cite this article
W. Yuan, R.C. McKinstry, J.S. Shimony, M. Altaye, S.K. Powell, J.M. Phillips, D.D. Limbrick, S.K. Holland, B.V. Jones, A. Rajagopal, S. Simpson, D. Mercer, F.T. Mangano
Diffusion Tensor Imaging Properties and Neurobehavioral Outcomes in Children with Hydrocephalus
American Journal of Neuroradiology Feb 2013, 34 (2) 439-445; DOI: 10.3174/ajnr.A3218

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Diffusion Tensor Imaging Properties and Neurobehavioral Outcomes in Children with Hydrocephalus
W. Yuan, R.C. McKinstry, J.S. Shimony, M. Altaye, S.K. Powell, J.M. Phillips, D.D. Limbrick, S.K. Holland, B.V. Jones, A. Rajagopal, S. Simpson, D. Mercer, F.T. Mangano
American Journal of Neuroradiology Feb 2013, 34 (2) 439-445; DOI: 10.3174/ajnr.A3218
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