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Article CommentarySpine Imaging and Spine Image-Guided Interventions

Diffusion Tensor Imaging Correlates with the Clinical Assessment of Disease Severity in Cervical Spondylotic Myelopathy and Predicts Outcome following Surgery

J.G.A. Jones, S.Y. Cen, R.M. Lebel, P.C. Hsieh and M. Law
American Journal of Neuroradiology February 2013, 34 (2) 471-478; DOI: https://doi.org/10.3174/ajnr.A3199
J.G.A. Jones
aFrom the Departments of Radiology (J.G.A.J., M.L.)
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S.Y. Cen
cDepartment of Biokinesiology & Physical Therapy (S.Y.C.), Herman Ostrow School of Dentistry of USC
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R.M. Lebel
dMing Hsieh Department of Electrical Engineering (R.M.L.), USC Viterbi School of Engineering, Los Angeles, California.
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P.C. Hsieh
bNeurological Surgery (P.C.H.), USC Keck School of Medicine
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M. Law
aFrom the Departments of Radiology (J.G.A.J., M.L.)
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References

  1. 1.↵
    1. Bernhardt M,
    2. Hynes RA,
    3. Blume HW,
    4. et al
    . Cervical spondylotic myelopathy. J Bone Joint Surg Am 1993;75:119–28
    PubMedWeb of Science
  2. 2.↵
    1. Boden SD,
    2. McCowin PR,
    3. Davis DO,
    4. et al
    . Abnormal magnetic-resonance scans of the cervical spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am 1990;72:1178–84
    PubMed
  3. 3.↵
    1. Levine DN
    . Pathogenesis of cervical spondylotic myelopathy. J Neurol Neurosurg Psychiatry 1997;62:334–40
    Abstract/FREE Full Text
  4. 4.↵
    1. Budzik J,
    2. Balbi V,
    3. Le Thuc V,
    4. et al
    . Diffusion tensor imaging and fibre tracking in cervical spondylotic myelopathy. Eur Radiol 2010;21:426–33
    PubMed
  5. 5.↵
    1. Kara B,
    2. Celik A,
    3. Karadereler S,
    4. et al
    . The role of DTI in early detection of cervical spondylotic myelopathy: a preliminary study with 3-T MRI. Neuroradiology 2011;53:609–16
    CrossRefPubMed
  6. 6.↵
    1. Mamata H,
    2. Jolesz FA,
    3. Maier SE
    . Apparent diffusion coefficient and fractional anisotropy in spinal cord: age and cervical spondylosis-related changes. J Magn Reson Imaging 2005;22:38–43
    CrossRefPubMed
  7. 7.↵
    1. Jones J,
    2. Lerner A,
    3. Kim PE,
    4. et al
    . Diffusion tensor imaging in the assessment of ossification of the posterior longitudinal ligament: a report on preliminary results in 3 cases and review of the literature. Neurosurg Focus 2011;30:E14
    PubMed
  8. 8.↵
    1. Beaulieu C
    . The basis of anisotropic water diffusion in the nervous system—a technical review. NMR Biomed 2002;15:435–55
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Tsuchiya K,
    2. Katase S,
    3. Fujikawa A,
    4. et al
    . Diffusion-weighted MRI of the cervical spinal cord using a single-shot fast spin-echo technique: findings in normal subjects and in myelomalacia. Neuroradiology 2003;45:90–94
    PubMedWeb of Science
  10. 10.↵
    1. Song SK,
    2. Sun SW,
    3. Ramsbottom MJ,
    4. et al
    . Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002;17:1429–36
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Fernandez de Rota JJ,
    2. Meschian S,
    3. Fernandez de Rota A,
    4. et al
    . Cervical spondylotic myelopathy due to chronic compression: the role of signal intensity changes in magnetic resonance images. J Neurosurg Spine 2007;6:17–22
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Suri A,
    2. Chabbra RP,
    3. Mehta VS,
    4. et al
    . Effect of intramedullary signal changes on the surgical outcome of patients with cervical spondylotic myelopathy. Spine J 2003;3:33–45
    CrossRefPubMed
  13. 13.↵
    1. Hori M,
    2. Okubo T,
    3. Aoki S,
    4. et al
    . Line scan diffusion tensor MRI at low magnetic field strength: feasibility study of cervical spondylotic myelopathy in an early clinical stage. J Magn Reson Imaging 2006;23:183–88
    CrossRefPubMed
  14. 14.↵
    1. Demir A,
    2. Ries M,
    3. Moonen CT,
    4. et al
    . Diffusion-weighted MR imaging with apparent diffusion coefficient and apparent diffusion tensor maps in cervical spondylotic myelopathy. Radiology 2003;229:37–43
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Healy JF,
    2. Healy BB,
    3. Wong WH,
    4. et al
    . Cervical and lumbar MRI in asymptomatic older male lifelong athletes: frequency of degenerative findings. J Comput Assist Tomogr 1996;20:107–12
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Kang M,
    2. Anderer E,
    3. Elliott R,
    4. et al
    . Diffusion tensor imaging of the spondylotic cervical spinal cord: a preliminary study of quantifiable markers in the evaluation for surgical decompression. Internet J Head Neck Surg 2011;5
  17. 17.↵
    1. Parker SL,
    2. Adogwa O,
    3. Paul AR,
    4. et al
    . Utility of minimum clinically important difference in assessing pain, disability, and health state after transforaminal lumbar interbody fusion for degenerative lumbar spondylolisthesis. J Neurosurg Spine 2011;14:598–604
    PubMedWeb of Science
  18. 18.↵
    1. Nurick S
    . The pathogenesis of the spinal cord disorder associated with cervical spondylosis. Brain 1972;95:87–100
    FREE Full Text
  19. 19.↵
    1. Benzel EC,
    2. Lancon J,
    3. Kesterson L,
    4. et al
    . Cervical laminectomy and dentate ligament section for cervical spondylotic myelopathy. J Spinal Disord 1991;4:286–95
    PubMedWeb of Science
  20. 20.↵
    1. Vernon H,
    2. Mior S
    . The Neck Disability Index: a study of reliability and validity. J Manipulative Physiol Ther 1991;14:409–15
    PubMedWeb of Science
  21. 21.↵
    1. Ware JE,
    2. Sherbourne CD
    . The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30:473–83
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. King JT Jr.,
    2. McGinnis KA,
    3. Roberts MS
    . Quality of life assessment with the medical outcomes study short form-36 among patients with cervical spondylotic myelopathy. Neurosurgery 2003:52:113–20; discussion 121
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. King JT,
    2. Roberts MS
    . Validity and reliability of the Short Form-36 in cervical spondylotic myelopathy. J Neurosurg 2002;97:180–85
    PubMed
  24. 24.↵
    1. Wetzel SG,
    2. Cha S,
    3. Johnson G,
    4. et al
    . Relative cerebral blood volume measurements in intracranial mass lesions: interobserver and intraobserver reproducibility study. Radiology 2002;224:797–803
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Wada E,
    2. Ohmura M,
    3. Yonenobu K
    . Intramedullary changes of the spinal cord in cervical spondylotic myelopathy. Spine (Phila Pa 1976) 1995;20:2226–32
    CrossRef
  26. 26.↵
    1. Kang Y,
    2. Lee JW,
    3. Koh YH,
    4. et al
    . New MRI grading system for the cervical canal stenosis. AJR Am J Roentgenol 2011;197:W134–40
    CrossRefPubMed
  27. 27.↵
    1. Henderson L,
    2. Kulik G,
    3. Richarme D,
    4. et al
    . Is spinal stenosis assessment dependent on slice orientation? A magnetic resonance imaging study. Eur Spine J 2011 [Epub ahead of print]
  28. 28.↵
    1. Mayrent SL
    . Epidemiology in Medicine. Boston: Lippincott Williams & Wilkins; 1987:287–304
  29. 29.↵
    1. Law MD,
    2. Bernhardt M,
    3. White AA
    . Cervical spondylotic myelopathy: a review of surgical indications and decision making. Yale J Biol Med 1993;66:165–77
    PubMed
  30. 30.↵
    1. Kerkovský M,
    2. Bednarík J,
    3. Dušek L,
    4. et al
    . Magnetic resonance diffusion tensor imaging in patients with cervical spondylotic spinal cord compression: correlations between clinical and electrophysiological findings. Spine (Phila Pa 1976) 2012;37:48–56
    CrossRef
  31. 31.↵
    1. Facon D,
    2. Ozanne A,
    3. Fillard P,
    4. et al
    . MR diffusion tensor imaging and fiber tracking in spinal cord compression. AJNR Am J Neuroradiol 2005;26:1587–94
    Abstract/FREE Full Text
  32. 32.↵
    1. Guleria S,
    2. Gupta RK,
    3. Saksena S,
    4. et al
    . Retrograde wallerian degeneration of cranial corticospinal tracts in cervical spinal cord injury patients using diffusion tensor imaging. J Neurosci Res 2008;86:2271–80
    CrossRefPubMed
  33. 33.↵
    1. Saritas EU,
    2. Cunningham CH,
    3. Lee JH,
    4. et al
    . DWI of the spinal cord with reduced FOV single-shot EPI. Magn Reson Med 2008;60:468–73
    CrossRefPubMed
  34. 34.↵
    1. Zaharchuk G,
    2. Saritas EU,
    3. Andre JB,
    4. et al
    . Reduced field-of-view diffusion imaging of the human spinal cord: comparison with conventional single-shot echo-planar imaging. AJNR Am J Neuroradiol 2011;32:813–20
    Abstract/FREE Full Text
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American Journal of Neuroradiology: 34 (2)
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J.G.A. Jones, S.Y. Cen, R.M. Lebel, P.C. Hsieh, M. Law
Diffusion Tensor Imaging Correlates with the Clinical Assessment of Disease Severity in Cervical Spondylotic Myelopathy and Predicts Outcome following Surgery
American Journal of Neuroradiology Feb 2013, 34 (2) 471-478; DOI: 10.3174/ajnr.A3199

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Diffusion Tensor Imaging Correlates with the Clinical Assessment of Disease Severity in Cervical Spondylotic Myelopathy and Predicts Outcome following Surgery
J.G.A. Jones, S.Y. Cen, R.M. Lebel, P.C. Hsieh, M. Law
American Journal of Neuroradiology Feb 2013, 34 (2) 471-478; DOI: 10.3174/ajnr.A3199
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