Article Figures & Data
Figures
- Fig. 1.
Direction-encoded color map (A) showing the genu of the CC and splenium of the CC in red, meaning that the fibers are left-right oriented (or vice versa). The ROIs are reproduced on the main eigenvalue, E1 (B); the middle eigenvalue, E2 (C); and the minor eigenvalue, E3, maps (D).
- Fig. 2.
Estimated marginal means corrected for postconceptional age of parallel diffusion (A), perpendicular diffusion (B), apparent diffusion coefficient (C), and fractional anisotropy (D) of the HC and presurgical (presurg) groups. The DTI of the genu of the CC in the presurgical patients indicates a significantly higher E23 (P = .018), higher ADC (P = .026), and lower FA (P = .033). In the splenium of the CC, we measured significantly lower FA (P = .033) in the presurg groups compared with the HC.
- Fig. 3.
Estimated marginal means corrected for postconceptional age of parallel diffusion, E1 (A); perpendicular diffusion, E23 (B); ADC (C); and FA (D) of the HC and postsurgical (postsurg) groups. The DTI in the genu of the CC in the postsurg group indicated a significantly higher E23 (P = .018), higher ADC (P = .026), and lower FA (P = .033) than those in the HC group. No differences were reported in the splenium of the CC.
- Fig. 4.
Estimated marginal means corrected for postconceptional age of parallel diffusion, E1 (A); perpendicular diffusion, E23 (B); ADC (C); and FA (D) of the postsurgical (postsurg) and presurgical (presurg) groups. DTI in the genu of the CC and splenium of the CC in the postsurg group reveals higher E23, higher ADC, and lower FA than those in the presurg group. The E1 is higher in the genu of the CC and lower in the splenium of the CC of the postsurg compared with the presurg group, but these differences are significant.
Tables
- Table 1:
Characteristics of the 15 patients who had both pre- and postoperative MRI, including DTI, and 11 healthy controls
Patients (n = 15) Healthy Controls (n = 11) Mean SD Min Max Med Mean SD Min Max Med Gestational age (wk) 39 1 37 41 39 39 1 38 41 40 Birth weight (g) 3381 452 2560 3990 3340 3466 417 3000 4160 3500 From birth to 1st MRI (days) 8 6 3 27 8 26 5 15 32 26 From birth to 2nd MRI (days) 29 9 16 52 27 From 1st to 2nd MRI (days) 21 8 11 42 20 From surgery to 2nd MRI (days) 14 6 7 28 12 Note:—Min indicates minimum; Max, maximum; Med, median.
- Table 2:
Percentage changes corrected for age in the GCC and SCC measured among Post, Pre, and HC groups
GCC SCC E1 (%) E23 (%) ADC (%) FA (%) E1 (%) E23 (%) ADC (%) FA (%) Pre vs HC 1.68 10.94 5.79 −8.20 −0.84 13.93 5.30 −10.48 Post vs HC 4.93 17.54 10.35 −9.40 0.60 13.98 6.18 −9.58 Pre vs Post 2.35 8.79 5.28 −6.33 −1.03 5.69 1.94 −6.26 Note:—Pre indicates presurgery; Post, postsurgery; GCC, genu of the CC; SCC, splenium of the CC.
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