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Grade Number Percent Age WMH (ml) Mean SD Range Median Q1-Q3 Range 0 241 43.1% 46.7 8.8 25–72 0.65 0.43–0.91 0.14–2.20 1 255 45.6% 51.4 8.9 27–71 1.01 0.71–1.42 0.13–5.51 2 49 8.8% 58.6 7.9 37–72 2.16 1.42–3.38 0.55–9.69 3 14 2.5% 64.2 5 57–72 13.97 7.15–30.18 4.53–83.18 - Table 2:
Association between measures of WMH and cognitive function using MoCA cutoffs for cognitive deficit as originally published and as established in our cohort
Normal (MoCA>25) Deficit (MoCA≤25) P Value Normal (MoCA>19) Deficit (MoCA≤19) P Value N (%) 210 (41.2) 300 (58.8) 441 (86.5) 69 (13.5) Visual Scalea Absent (%) 103 117 0.050 199 21 0.001 Minimal (%) 92 143 204 31 Moderate (%) 12 30 29 13 Advanced (%) 3 10 9 4 Automated Volumeb (mL), median (range) 0.815 (0.14–39.64) 0.95 (0.13–83.18) 0.014 0.90 (0.13–83.18) 1.05 (0.14–45.48) 0.091
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