Article Figures & Data
Figures
- Fig 1.
Measurements of perfusion parameters in a 22-year-old man with PCNSL. Axial contrast-enhanced MPRAGE (A) shows an enhancing mass in the right temporo-occipital region. B, On contrast-enhanced MPRAGE, 2 ROIs are placed, one over the entire enhancing tumor and another at the contralateral NAWM for the measurement of CBV (C), corrected CBV (D), and K2 (E), respectively.
- Fig 2.
Measurements of perfusion parameters in a 40-year-old woman with glioblastoma. Axial contrast-enhanced MPRAGE (A) shows an enhancing mass in the right lateral frontal region. B, On contrast-enhanced MPRAGE, 2 ROIs are placed, one over the entire enhancing tumor and another at the contralateral NAWM for the measurement of CBV (C), corrected CBV (D), and K2 (E), respectively.
- Fig 3.
Receiver operating characteristic curve analysis for comparisons of the diagnostic performance of CBV, corrected CBV, and K2.
Tables
- Table 1:
Quantitative comparisons of perfusion parameters between PCNSLs and glioblastomasa
Parameter PCNSL Glioblastoma P Value 95% CI CBV ratio 1.16 ± 0.66 5.01 ± 2.01 <.001 −4.82 to −2.84 Corrected CBV ratio 2.28 ± 0.60 5.47 ± 2.05 <.001 −4.19 to −2.18 K2 1.88 ± 1.11 0.79 ± 0.68 .001 0.47–1.71 Note:—CI indicates confidence interval.
↵a Data are means.
Parameter AUC 95% CI P Value CV SEN SPE Accuracy CBV ratio 0.984 0.952–1.000 <.001 1.88 100 86.7 94.2 Corrected CBV ratio 0.940 0.861–1.000 <.001 3.01 90 93.3 91.4 2.08 100 46.7 77.1 K2 0.788 0.624–0.953 .004 1.2 75 80.0 77.1 Note:—CI indicates confidence interval; CV, cutoff value; SEN, sensitivity; SPE, specificity; AUC, area under the curve; ROC, receiver operating characteristic curve analysis.
↵a Data of sensitivity, specificity, and accuracy are in percentages.
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