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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention
Open Access

Safety and Efficacy of Endovascular Sonolysis Using the EkoSonic Endovascular System in Patients with Acute Stroke

M. Kuliha, M. Roubec, T. Jonszta, J. Krajča, D. Czerny, A. Krajina, K. Langová, R. Herzig, V. Procházka and D. Školoudík
American Journal of Neuroradiology July 2013, 34 (7) 1401-1406; DOI: https://doi.org/10.3174/ajnr.A3416
M. Kuliha
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
bComprehensive Stroke Center (M.K., R.H., D.Š.), Department of Neurology, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic
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M. Roubec
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
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T. Jonszta
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
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J. Krajča
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
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D. Czerny
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
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A. Krajina
cComprehensive Stroke Center, Department of Radiology (A.K.), Faculty of Medicine, Charles University and University Hospital Hradec Králové, Hradec Králové, Czech Republic
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K. Langová
dDepartment of Biophysics (K.L.), Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacký University, Olomouc, Czech Republic.
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R. Herzig
bComprehensive Stroke Center (M.K., R.H., D.Š.), Department of Neurology, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic
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V. Procházka
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
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D. Školoudík
aFrom the Comprehensive Stroke Center (M.K., M.R., D.Š., T.J., J.K., D.C., V.P.), Department of Neurology, Faculty of Medicine, Ostrava University and University Hospital Ostrava, Ostrava, Czech Republic
bComprehensive Stroke Center (M.K., R.H., D.Š.), Department of Neurology, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic
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REFERENCES

  1. 1.↵
    1. Bar M,
    2. Školoudík D,
    3. Roubec M,
    4. et al
    . Transcranial duplex sonography and CT angiography in acute stroke patients. J Neuroimaging 2010;20:240–45
    PubMed
  2. 2.↵
    1. Fieschi C,
    2. Argentino C,
    3. Lenzi GL,
    4. et al
    . Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours. J Neurol Sci 1989;91:311–21
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Furlan A,
    2. Higashida R,
    3. Wechsler L,
    4. et al
    . Intra-arterial prourokinase for acute ischemic stroke: the PROACT II study—a randomized controlled trial Prolyse in Acute Cerebral Thromboembolism. JAMA 1999;282:2003–11
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Wunderlich MT,
    2. Goertler M,
    3. Postert T,
    4. et al
    . Recanalization after thrombolysis—does a recanalization time window exist? Neurology 2007;68:1364–68
    CrossRef
  5. 5.↵
    1. Rha JH,
    2. Saver JL
    . The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 2007;38:967–73
    Abstract/FREE Full Text
  6. 6.↵
    1. van der Worp HB,
    2. van Gijn J
    . Clinical practice: acute ischemic stroke. N Engl J Med 2007;357:572–79
    CrossRefPubMedWeb of Science
  7. 7.↵
    Tissue plasminogen activator for acute ischemic stroke: National Institute of Neurological Disorders and Stroke rt-PA Study Group. N Engl J Med 1995;333:1581–87
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Smith WS,
    2. Sung G,
    3. Starkman S,
    4. et al
    . Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432–38
    Abstract/FREE Full Text
  9. 9.↵
    1. Kerber CW,
    2. Barr JD,
    3. Berger RM,
    4. et al
    . Snare retrieval of intracranial thrombus in patients with acute stroke. J Vasc Interv Radiol 2002;13:1269–74
    PubMedWeb of Science
  10. 10.↵
    1. Smith WS,
    2. Sung G,
    3. Saver J,
    4. et al
    . Mechanical Thrombectomy for Acute Ischemic Stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205–12
    Abstract/FREE Full Text
  11. 11.↵
    Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–68
    Abstract/FREE Full Text
  12. 12.↵
    1. Grunwald IQ,
    2. Wakhloo AK,
    3. Walter S,
    4. et al
    . Endovascular stroke treatment today. AJNR Am J Neuroradiol 2011;32:238–43
    Abstract/FREE Full Text
  13. 13.↵
    1. Machi P,
    2. Costalat V,
    3. Lobotesis K,
    4. et al
    . Solitaire FR thrombectomy system: immediate results in 56 consecutive acute ischemic stroke patients. J Neurointerv Surg 2012;4:62–66
    Abstract/FREE Full Text
  14. 14.↵
    1. Costalat V,
    2. Machi P,
    3. Lobotesis K,
    4. et al
    . Rescue, combined, and stand-alone thrombectomy in the management of large vessel occlusion stroke using the Solitaire device: a prospective 50-patient single-center study—timing, safety, and efficacy. Stroke 2011;42:1929–35
    Abstract/FREE Full Text
  15. 15.↵
    1. Nogueira RG,
    2. Levy EI,
    3. Gounis M,
    4. et al
    . The Trevo device: preclinical data of a novel stroke thrombectomy device in two different animal models of arterial thrombo-occlusive disease. J Neurointerv Surg 2011;4:295–300
    PubMed
  16. 16.↵
    1. Mendonça N,
    2. Flores A,
    3. Pagola J,
    4. et al
    . Trevo system: single-center experience with a novel mechanical thrombectomy device. J Neuroimaging 2011 Dec 30. [Epub ahead of print]
  17. 17.↵
    1. Mourand I,
    2. Brunel H,
    3. Costalat V,
    4. et al
    . Mechanical thrombectomy in acute ischemic stroke: catch device. AJNR Am J Neuroradiol 2011;32:1381–85
    Abstract/FREE Full Text
  18. 18.↵
    1. Levy EI,
    2. Siddiqui AH,
    3. Crumlish A,
    4. et al
    . First Food and Drug Administration-approved prospective trial of primary intracranial stenting for acute stroke: SARIS (Stent-Assisted Recanalization In Acute Ischemic Stroke). Stroke 2009;40:3552–56
    Abstract/FREE Full Text
  19. 19.↵
    1. Linfante I,
    2. Samaniego EA,
    3. Geisbüsch P,
    4. et al
    . Self-expandable stents in the treatment of acute ischemic stroke refractory to current thrombectomy devices. Stroke 2011;42:2636–68
    Abstract/FREE Full Text
  20. 20.↵
    1. Skoloudik D,
    2. Bar M,
    3. Skoda O,
    4. et al
    . Safety and efficacy of the sonographic acceleration of the middle cerebral artery recanalization: results of the pilot thrombotripsy study. Ultrasound Med Biol 2008;34:1775–82
    CrossRefPubMed
  21. 21.↵
    1. Alexandrov AV,
    2. Molina CA,
    3. Grotta JC,
    4. et al
    . Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med 2004;351:2170–78
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Mahon BR,
    2. Nesbit GM,
    3. Barnwell SL,
    4. et al
    . North American clinical experience with the EKOS MicroLysUS infusion catheter for the treatment of embolic stroke. AJNR Am J Neuroradiol 2003;24:534–38
    Abstract/FREE Full Text
  23. 23.↵
    IMS II Trial Investigators. The Interventional Management of Stroke (IMS) II Study. Stroke 2007;38:2127–35
    Abstract/FREE Full Text
  24. 24.↵
    1. Jonszta T,
    2. Czerný D,
    3. Skoloudik D,
    4. et al
    . EkoSonicSV endovascular system for recanalization of the basilar artery occlusion. Vasa 2011;40:408–13
    CrossRefPubMed
  25. 25.↵
    1. Hacke W,
    2. Kaste M,
    3. Bluhmki E,
    4. et al
    . Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317–29
    CrossRefPubMedWeb of Science
  26. 26.↵
    European Stroke Organisation [ESO] Executive Committee and the ESO Writing Committee 2008. Update Guidelines January 2009 New Elements. http://www.eso-stroke.org/pdf/ESO_Guideline_Update_Jan_2009.pdf. Accessed September 15, 2012
  27. 27.↵
    1. Toni D,
    2. Lorenzano S,
    3. Puca E,
    4. et al
    . The SITS-MOST registry. Neurol Sci 2006;27(suppl 3):260–62
    CrossRef
  28. 28.↵
    1. Noser EA,
    2. Shaltoni HM,
    3. Hall CE,
    4. et al
    . Aggressive mechanical clot disruption: a safe adjunct to thrombolytic therapy in acute stroke? Stroke 2005;36:292-96
    Abstract/FREE Full Text
  29. 29.↵
    1. Rosenschein U,
    2. Roth A,
    3. Rassin T,
    4. et al
    . Analysis of coronary ultrasound thrombolysis endpoints in acute myocardial infarction (ACUTE trial): results of the feasibility phase. Circulation 1997;95:1411–16
    Abstract/FREE Full Text
  30. 30.↵
    1. Ganguli S,
    2. Kalva S,
    3. Oklu R,
    4. et al
    . Efficacy of lower-extremity venous thrombolysis in the setting of congenital absence or atresia of the inferior vena cava. Cardiovasc Intervent Radiol 2011; 35:1053–58
    PubMed
  31. 31.↵
    1. Grommes J,
    2. Strijkers R,
    3. Greiner A,
    4. et al
    . Safety and feasibility of ultrasound-accelerated catheter-directed thrombolysis in deep vein thrombosis. Eur J Vasc Endovasc Surg 2011;41:526–32
    CrossRefPubMed
  32. 32.↵
    1. Shah KJ,
    2. Scileppi RM,
    3. Franz RW
    . Treatment of pulmonary embolism using ultrasound-accelerated thrombolysis directly into pulmonary arteries. Vasc Endovascular Surg 2011;45:541–48
    Abstract/FREE Full Text
  33. 33.↵
    1. Lin PH,
    2. Annambhotla S,
    3. Bechara CF,
    4. et al
    . Comparison of percutaneous ultrasound-accelerated thrombolysis versus catheter-directed thrombolysis in patients with acute massive pulmonary embolism. Vascular 2009;17(suppl 3):S137–47
    Abstract/FREE Full Text
  34. 34.↵
    1. Motarjeme A
    . Ultrasound-enhanced thrombolysis. J Endovasc Ther 2007;14:251–56
    CrossRefPubMed
  35. 35.↵
    1. Ouriel K,
    2. Veith FJ,
    3. Sasahara AA
    . A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs: Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med 1998;338:1105–11
    CrossRefPubMedWeb of Science
  36. 36.↵
    1. Francis CW,
    2. Blinc A,
    3. Lee S,
    4. et al
    . Ultrasound accelerates transport of recombinant tissue plasminogen activator into clots. Ultrasound Med Biol 1995;21:419–24
    CrossRefPubMedWeb of Science
  37. 37.↵
    1. Skoloudík D,
    2. Fadrna T,
    3. Roubec M,
    4. et al
    . Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. Ultrasound Med Biol 2010;36:1052–59
    CrossRefPubMed
  38. 38.↵
    1. Skoloudík D,
    2. Fadrná T,
    3. Bar M,
    4. et al
    . Changes in haemocoagulation in healthy volunteers after a 1-hour thrombotripsy using a diagnostic 2–4 MHz transcranial probe. J Thromb Thrombolysis 2008;26:119–24
    CrossRefPubMed
  39. 39.↵
    1. Suchkova VN,
    2. Baggs RB,
    3. Francis CW
    . Effect of 40-kHz ultrasound on acute thrombotic ischemia in a rabbit femoral artery thrombosis model: enhancement of thrombolysis and improvement in capillary muscle perfusion. Circulation 2000;101:2296–301
    Abstract/FREE Full Text
  40. 40.↵
    1. Bardoň P,
    2. Skoloudik D,
    3. Langova K,
    4. et al
    . Changes in blood flow velocity in the radial artery during 1-hour ultrasound monitoring with a 2-MHz transcranial probe: a pilot study. J Clin Ultrasound 2010;38:493–96
    CrossRefPubMed
  41. 41.↵
    1. Harvey EN
    . Biological aspects of ultrasonic waves, a general survey. Biol Bull 1930;59:306–25
    FREE Full Text
  42. 42.↵
    1. Schonewille WJ,
    2. Algra A,
    3. Serena J,
    4. et al
    . Outcome in patients with basilar artery occlusion treated conventionally. J Neurol Neurosurg Psychiatry 2005;76:1238–41
    Abstract/FREE Full Text
  43. 43.↵
    1. Baird TA,
    2. Muir KW,
    3. Bone I
    . Basilar artery occlusion. Neurocrit Care 2004;1:319–29
    CrossRefPubMed
  44. 44.↵
    1. Schonewille WJ,
    2. Wijman CA,
    3. Michel P,
    4. et al
    . Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study. Lancet Neurol 2009;8:724–30
    CrossRefPubMedWeb of Science
  45. 45.↵
    1. Jung S,
    2. Mono ML,
    3. Fischer U,
    4. et al
    . Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis. Stroke 2011;42:1946–51
    Abstract/FREE Full Text
  46. 46.↵
    1. Tomsick T
    . TIMI, TIBI, TICI: I came, I saw, I got confused. AJNR Am J Neuroradiol 2007;28:382–84
    FREE Full Text
  47. 47.↵
    1. Kallmes DF
    . If you are not confused, then you are not paying attention. AJNR Am J Neuroradiol 2012;33:975–76
    FREE Full Text
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Cite this article
M. Kuliha, M. Roubec, T. Jonszta, J. Krajča, D. Czerny, A. Krajina, K. Langová, R. Herzig, V. Procházka, D. Školoudík
Safety and Efficacy of Endovascular Sonolysis Using the EkoSonic Endovascular System in Patients with Acute Stroke
American Journal of Neuroradiology Jul 2013, 34 (7) 1401-1406; DOI: 10.3174/ajnr.A3416

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Safety and Efficacy of Endovascular Sonolysis Using the EkoSonic Endovascular System in Patients with Acute Stroke
M. Kuliha, M. Roubec, T. Jonszta, J. Krajča, D. Czerny, A. Krajina, K. Langová, R. Herzig, V. Procházka, D. Školoudík
American Journal of Neuroradiology Jul 2013, 34 (7) 1401-1406; DOI: 10.3174/ajnr.A3416
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