Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePatient Safety
Open Access

Effects of Increased Image Noise on Image Quality and Quantitative Interpretation in Brain CT Perfusion

K. Juluru, J.C. Shih, A. Raj, J.P. Comunale, H. Delaney, E.D. Greenberg, C. Hermann, Y.B. Liu, A. Hoelscher, N. Al-Khori and P.C. Sanelli
American Journal of Neuroradiology August 2013, 34 (8) 1506-1512; DOI: https://doi.org/10.3174/ajnr.A3448
K. Juluru
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.C. Shih
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Raj
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.P. Comunale
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Delaney
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E.D. Greenberg
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. Hermann
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Y.B. Liu
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Hoelscher
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N. Al-Khori
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.C. Sanelli
aFrom the Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

REFERENCES

  1. 1.↵
    1. Provenzale JM,
    2. Shah K,
    3. Patel U,
    4. et al
    . Systematic review of CT and MR perfusion imaging for assessment of acute cerebrovascular disease. AJNR Am J Neuroradiol 2008;29:1476–82
    Abstract/FREE Full Text
  2. 2.↵
    1. Turk A,
    2. Magarik JA,
    3. Chaudry I,
    4. et al
    . CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective. J Neurointerv Surg 2011;4:261–65
    PubMed
  3. 3.↵
    1. Konstas AA,
    2. Wintermark M,
    3. Lev MH
    . CT perfusion imaging in acute stroke. Neuroimaging Clin N Am 2011;21:215–38, ix.
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Suzuki K,
    2. Morita S,
    3. Masukawa A,
    4. et al
    . Utility of CT perfusion with 64-row multi-detector CT for acute ischemic brain stroke. Emerg Radiol 2011;18:95–101
    CrossRefPubMed
  5. 5.↵
    1. Loftus ML,
    2. Minkowitz S,
    3. Tsiouris AJ,
    4. et al
    . Utilization guidelines for reducing radiation exposure in the evaluation of aneurysmal subarachnoid hemorrhage: a practice quality improvement project. AJR Am J Roentgenol 2010;195:176–80
    CrossRefPubMed
  6. 6.↵
    1. Sanelli PC,
    2. Jou A,
    3. Gold R,
    4. et al
    . Using CT perfusion during the early baseline period in aneurysmal subarachnoid hemorrhage to assess for development of vasospasm. Neuroradiology 2011;53:425–34
    CrossRefPubMed
  7. 7.↵
    1. Wintermark M,
    2. Ko NU,
    3. Smith WS,
    4. et al
    . Vasospasm after subarachnoid hemorrhage: utility of perfusion CT and CT angiography on diagnosis and management. AJNR Am J Neuroradiol 2006;27:26–34
    Abstract/FREE Full Text
  8. 8.↵
    1. Sanelli PC,
    2. Ugorec I,
    3. Johnson CE,
    4. et al
    . Using quantitative CT perfusion for evaluation of delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage. AJNR Am J Neuroradiol 2011;32:2047–53
    Abstract/FREE Full Text
  9. 9.↵
    1. Ramli N,
    2. Rahmat K,
    3. Mah E,
    4. et al
    . Use of permeability surface area-product to differentiate intracranial tumours from abscess. Biomed Imaging Interv J 2009;5:e6
    PubMed
  10. 10.↵
    1. Sergides I,
    2. Hussain Z,
    3. Naik S,
    4. et al
    . Utilization of dynamic CT perfusion in the study of intracranial meningiomas and their surrounding tissue. Neurol Res 2009;31:84–89
    CrossRefPubMed
  11. 11.↵
    1. Ding B,
    2. Ling HW,
    3. Chen KM,
    4. et al
    . Comparison of cerebral blood volume and permeability in preoperative grading of intracranial glioma using CT perfusion imaging. Neuroradiology 2006;48:773–81
    CrossRefPubMed
  12. 12.↵
    1. Fainardi E,
    2. Di Biase F,
    3. Borrelli M,
    4. et al
    . Potential role of CT perfusion parameters in the identification of solitary intra-axial brain tumor grading. Acta Neurochir Suppl 2010;106:283–87
    CrossRefPubMed
  13. 13.↵
    1. Smith AB,
    2. Dillon WP,
    3. Gould R,
    4. et al
    . Radiation dose-reduction strategies for neuroradiology CT protocols. AJNR Am J Neuroradiol 2007;28:1628–32
    Abstract/FREE Full Text
  14. 14.↵
    1. Wintermark M,
    2. Smith WS,
    3. Ko NU,
    4. et al
    . Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients. AJNR Am J Neuroradiol 2004;25:720–29
    Abstract/FREE Full Text
  15. 15.↵
    1. Britten AJ,
    2. Crotty M,
    3. Kiremidjian H,
    4. et al
    . The addition of computer simulated noise to investigate radiation dose and image quality in images with spatial correlation of statistical noise: an example application to x-ray CT of the brain. Br J Radiol 2004;77:323–28
    Abstract/FREE Full Text
  16. 16.↵
    1. Saito N,
    2. Kudo K,
    3. Sasaki T,
    4. et al
    . Realization of reliable cerebral-blood-flow maps from low-dose CT perfusion images by statistical noise reduction using nonlinear diffusion filtering. Radiol Phys Technol 2008;1:62–74
    CrossRefPubMed
  17. 17.↵
    1. Wintermark M,
    2. Maeder P,
    3. Thiran JP,
    4. et al
    . Quantitative assessment of regional cerebral blood flows by perfusion CT studies at low injection rates: a critical review of the underlying theoretical models. Eur Radiol 2001;11:1220–30
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Sanelli PC,
    2. Lev MH,
    3. Eastwood JD,
    4. et al
    . The effect of varying user-selected input parameters on quantitative values in CT perfusion maps. Acad Radiol 2004;11:1085–92
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Wintermark M,
    2. Lau BC,
    3. Chien J,
    4. et al
    . The anterior cerebral artery is an appropriate arterial input function for perfusion-CT processing in patients with acute stroke. Neuroradiology 2008;50:227–36
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Liang K-Y,
    2. Zeger SL
    . Longitudinal data analysis using generalized linear models. Biometrika 1986;73:13–22
    Abstract/FREE Full Text
  21. 21.↵
    1. Cunningham M
    . More than Just the Kappa Coefficient: A Program to Fully Characterize Inter-Rater Reliability between Two Raters [Internet]. SAS Global Forum 2009. 2009 [cited 2012 May 22]; Available from: http://support.sas.com/resources/papers/proceedings09/242–2009.pdf
  22. 22.↵
    1. Krissak R,
    2. Mistretta CA,
    3. Henzler T,
    4. et al
    . Noise reduction and image quality improvement of low dose and ultra low dose brain perfusion CT by HYPR-LR processing. PloS One 2011;6:e17098
    CrossRefPubMed
  23. 23.↵
    1. Mayo JR,
    2. Hartman TE,
    3. Lee KS,
    4. et al
    . CT of the chest: minimal tube current required for good image quality with the least radiation dose. AJR Am J Roentgenol 1995;164:603–07
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 34 (8)
American Journal of Neuroradiology
Vol. 34, Issue 8
1 Aug 2013
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Effects of Increased Image Noise on Image Quality and Quantitative Interpretation in Brain CT Perfusion
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
K. Juluru, J.C. Shih, A. Raj, J.P. Comunale, H. Delaney, E.D. Greenberg, C. Hermann, Y.B. Liu, A. Hoelscher, N. Al-Khori, P.C. Sanelli
Effects of Increased Image Noise on Image Quality and Quantitative Interpretation in Brain CT Perfusion
American Journal of Neuroradiology Aug 2013, 34 (8) 1506-1512; DOI: 10.3174/ajnr.A3448

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Effects of Increased Image Noise on Image Quality and Quantitative Interpretation in Brain CT Perfusion
K. Juluru, J.C. Shih, A. Raj, J.P. Comunale, H. Delaney, E.D. Greenberg, C. Hermann, Y.B. Liu, A. Hoelscher, N. Al-Khori, P.C. Sanelli
American Journal of Neuroradiology Aug 2013, 34 (8) 1506-1512; DOI: 10.3174/ajnr.A3448
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Safety of Intrathecal Gadobutrol in Various Doses
  • Impact of Kidney Function on CNS Gadolinium Deposition in Patients Receiving Repeated Doses of Gadobutrol
  • Contrast-Induced Acute Kidney Injury in Radiologic Management of Acute Ischemic Stroke in the Emergency Setting
Show more Patient Safety

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire