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This meta-analysis of the literature sought to identify differences between outcomes of patients treated with first- and second-generation aneurysm coils. Unfavorable outcome was defined as recanalization, less than 90% occlusion, and/or incomplete occlusion at follow-up. In 82 published articles, unfavorable outcomes were reported in 20% of patients treated with bare platinum coils, 23% with Matrix coils, 15% with HydroCoil, and 15% with Cerecyte coils. These differences were not statistically significant.

CT findings in 27 nontreated patients with oral squamous cell carcinoma were correlated with genomic analysis. Tumor enhancement correlated with presence of vascular endothelial growth factor while epidermal growth factor correlated with mass effect and perineural invasion. Thus, some CT findings may reflect genomic biomarkers.