Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleHead and Neck Imaging

Diffusion-Weighted Imaging of Orbital Masses: Multi-Institutional Data Support a 2-ADC Threshold Model to Categorize Lesions as Benign, Malignant, or Indeterminate

A.R. Sepahdari, L.S. Politi, V.K. Aakalu, H.J. Kim and A.A.K. Abdel Razek
American Journal of Neuroradiology January 2014, 35 (1) 170-175; DOI: https://doi.org/10.3174/ajnr.A3619
A.R. Sepahdari
aFrom the Department of Radiological Sciences (A.R.S., H.J.K.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L.S. Politi
bDepartment of Neuroradiology (L.S.P.), San Raffaele Institute of Science, Milan, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
V.K. Aakalu
cDepartment of Ophthalmology and Visual Sciences (V.K.A.), University of Illinois at Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.J. Kim
aFrom the Department of Radiological Sciences (A.R.S., H.J.K.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A.A.K. Abdel Razek
dDiagnostic Radiology Department (A.A.K.A.R.), Mansoura Faculty of Medicine, Mansoura, Egypt.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

REFERENCES

  1. 1.↵
    1. Shields J,
    2. Shields C,
    3. Scartozzi R
    . Survey of 1264 patients with orbital tumors and simulating lesions. 1. The 2002 Montgomery Lecture, part 1. Ophthalmology 2004;111:997–1008
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Mafee M,
    2. Karimi A,
    3. Shah J,
    4. et al
    . Anatomy and pathology of the eye: role of MR imaging and CT. Neuroimaging Clin North Am 2005;15:23–47
    CrossRef
  3. 3.↵
    1. Mafee MF,
    2. Edward DP,
    3. Koeller KK,
    4. et al
    . Lacrimal gland tumors and simulating lesions: clinicopathologic and MR imaging features. Radiol Clin North Am 1999;37:219–39, xii
    CrossRefPubMed
  4. 4.↵
    1. Mafee MF,
    2. Goodwin J,
    3. Dorodi S
    . Optic nerve sheath meningiomas: role of MR imaging. Radiol Clin North Am 1999;37:37–58, ix
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Mafee MF,
    2. Dorodi S,
    3. Pai E
    . Sarcoidosis of the eye, orbit, and central nervous system: role of MR imaging. Radiol Clin North Am 1999;37:73–87, x.
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Valvassori GE,
    2. Sabnis SS,
    3. Mafee RF,
    4. et al
    . Imaging of orbital lymphoproliferative disorders. Radiol Clin North Am 1999;37:135–50, x–xi
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Carroll GS,
    2. Haik BG,
    3. Fleming JC,
    4. et al
    . Peripheral nerve tumors of the orbit. Radiol Clin North Am 1999;37:195–202, xi–xii
    CrossRefPubMed
  8. 8.↵
    1. Akansel G,
    2. Hendrix L,
    3. Erickson BA,
    4. et al
    . MRI patterns in orbital malignant lymphoma and atypical lymphocytic infiltrates. Eur J Radiol 2005;53:175–81
    CrossRefPubMed
  9. 9.↵
    1. Smoker WR,
    2. Gentry LR,
    3. Yee NK,
    4. et al
    . Vascular lesions of the orbit: more than meets the eye. Radiographics 2008;28:185–204, quiz 325
    CrossRefPubMed
  10. 10.↵
    1. Razek AA
    . Diffusion-weighted magnetic resonance imaging of head and neck. J Comput Assist Tomogr 2010;34:808–15
    CrossRefPubMed
  11. 11.↵
    1. Roshdy N,
    2. Shahin M,
    3. Kishk H,
    4. et al
    . MRI in diagnosis of orbital masses. Curr Eye Res 2010;35:986–91
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Kapur R,
    2. Sepahdari AR,
    3. Mafee MF,
    4. et al
    . MR imaging of orbital inflammatory syndrome, orbital cellulitis, and orbital lymphoid lesions: the role of diffusion-weighted imaging. AJNR Am J Neuroradiol 2009;30:64–70
    Abstract/FREE Full Text
  13. 13.↵
    1. Sepahdari AR,
    2. Kapur R,
    3. Aakalu VK,
    4. et al
    . Diffusion-weighted imaging of malignant ocular masses: initial results and directions for further study. AJNR Am J Neuroradiol 2012;33:314–19
    Abstract/FREE Full Text
  14. 14.↵
    1. Sepahdari AR,
    2. Aakalu VK,
    3. Setabutr P,
    4. et al
    . Indeterminate orbital masses: restricted diffusion at MR imaging with echo-planar diffusion-weighted imaging predicts malignancy. Radiology 2010;256:554–64
    CrossRefPubMed
  15. 15.↵
    1. Sepahdari AR,
    2. Aakalu VK,
    3. Kapur R,
    4. et al
    . MRI of orbital cellulitis and orbital abscess: the role of diffusion-weighted imaging. AJR Am J Roentgenol 2009;193:W244–50
    CrossRefPubMed
  16. 16.↵
    1. Razek AA,
    2. Elkhamary S,
    3. Mousa A
    . Differentiation between benign and malignant orbital tumors at 3-T diffusion MR-imaging. Neuroradiology 2011;53:517–22
    CrossRefPubMed
  17. 17.↵
    1. Politi LS,
    2. Forghani R,
    3. Godi C,
    4. et al
    . Ocular adnexal lymphoma: diffusion-weighted MR imaging for differential diagnosis and therapeutic monitoring. Radiology 2010;256:565–74
    CrossRefPubMed
  18. 18.↵
    1. de Graaf P,
    2. Pouwels PJ,
    3. Rodjan F,
    4. et al
    . Single-shot turbo spin-echo diffusion-weighted imaging for retinoblastoma: initial experience. AJNR Am J Neuroradiol 2012;33:110–18
    Abstract/FREE Full Text
  19. 19.↵
    1. Srinivasan A,
    2. Dvorak R,
    3. Perni K,
    4. et al
    . Differentiation of benign and malignant pathology in the head and neck using 3T apparent diffusion coefficient values: early experience. AJNR Am J Neuroradiol 2008;29:40–44
    Abstract/FREE Full Text
  20. 20.↵
    1. Maeda M,
    2. Kato H,
    3. Sakuma H,
    4. et al
    . Usefulness of the apparent diffusion coefficient in line scan diffusion-weighted imaging for distinguishing between squamous cell carcinomas and malignant lymphomas of the head and neck. AJNR Am J Neuroradiol 2005;26:1186–92
    Abstract/FREE Full Text
  21. 21.↵
    1. Lope LA,
    2. Hutcheson KA,
    3. Khademian ZP
    . Magnetic resonance imaging in the analysis of pediatric orbital tumors: utility of diffusion-weighted imaging. J AAPOS 2010;14:257–62
    CrossRefPubMed
  22. 22.↵
    1. Yang BT,
    2. Wang YZ,
    3. Dong JY,
    4. et al
    . MRI study of solitary fibrous tumor in the orbit. AJR Am J Roentgenol 2012;199:W506–11
    CrossRefPubMed
  23. 23.↵
    1. Kamano H,
    2. Noguchi T,
    3. Yoshiura T,
    4. et al
    . Intraorbital lobular capillary hemangioma (pyogenic granuloma). Radiat Med 2008;26:609–12
    CrossRefPubMed
  24. 24.↵
    1. Chenevert TL,
    2. Galbán CJ,
    3. Ivancevic MK,
    4. et al
    . Diffusion coefficient measurement using a temperature-controlled fluid for quality control in multicenter studies. J Magn Reson Imaging 2011;34:983–87
    CrossRefPubMed
  25. 25.↵
    1. Chung EM,
    2. Specht CS,
    3. Schroeder JW
    . From the archives of the AFIP: pediatric orbit tumors and tumorlike lesions: neuroepithelial lesions of the ocular globe and optic nerve. Radiographics 2007;27:1159–86
    CrossRefPubMed
  26. 26.↵
    1. Bilgili Y,
    2. Unal B
    . Effect of region of interest on interobserver variance in apparent diffusion coefficient measures. AJNR Am J Neuroradiol 2004;25:108–11
    Abstract/FREE Full Text
  27. 27.↵
    1. Sasaki M,
    2. Yamada K,
    3. Watanabe Y,
    4. et al
    . Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study. Radiology 2008;249:624–30
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 35 (1)
American Journal of Neuroradiology
Vol. 35, Issue 1
1 Jan 2014
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Diffusion-Weighted Imaging of Orbital Masses: Multi-Institutional Data Support a 2-ADC Threshold Model to Categorize Lesions as Benign, Malignant, or Indeterminate
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
A.R. Sepahdari, L.S. Politi, V.K. Aakalu, H.J. Kim, A.A.K. Abdel Razek
Diffusion-Weighted Imaging of Orbital Masses: Multi-Institutional Data Support a 2-ADC Threshold Model to Categorize Lesions as Benign, Malignant, or Indeterminate
American Journal of Neuroradiology Jan 2014, 35 (1) 170-175; DOI: 10.3174/ajnr.A3619

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Diffusion-Weighted Imaging of Orbital Masses: Multi-Institutional Data Support a 2-ADC Threshold Model to Categorize Lesions as Benign, Malignant, or Indeterminate
A.R. Sepahdari, L.S. Politi, V.K. Aakalu, H.J. Kim, A.A.K. Abdel Razek
American Journal of Neuroradiology Jan 2014, 35 (1) 170-175; DOI: 10.3174/ajnr.A3619
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgements
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Arterial Spin-Labeling in the Assessment of Pediatric Nontraumatic Orbital Lesions
  • Orbital Lymphoproliferative Disorders (OLPDs): Value of MR Imaging for Differentiating Orbital Lymphoma from Benign OPLDs
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Hydrops Herniation into the Semicircular Canals
  • ASL Sensitivity for Head and Neck Paraganglioma
  • Post SRS Peritumoral Hyperintense Signal of VSs
Show more HEAD AND NECK IMAGING

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire